(TET ra BEN a zeen) Brand: Xenazine
• You must not use this medicine if you are allergic to tetrabenazine, or if you have severe or untreated depression, suicidal thoughts, liver malady, or past or gift breast cancer.
• Do not use tetrabenazine if you have taken reserpine within the past 20 days, or if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) within the past 14 days.
• Till you take tetrabenazine, speak your doctor if you have heart malady or a last history of heart onslaught, a private or family history of "Long QT syndrome," or a history of depression or suicidal thoughts or actions.
• Tetrabenazine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
• You may feel depressed or have thoughts about suicide when you first start taking this medicine. Your doctor will need to check you at regular visits during treatment.
• Stop taking tetrabenazine and call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, confusion, trouble swallowing, problems with balance, uncontrolled muscle movements, extreme drowsiness, or if you feel restless, agitated, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself.
• Tetrabenazine reduces the amount of determined chemicals in the body that are overly active in people with Huntington's disease.
• Tetrabenazine is used to treat Huntington's chorea (uncontrolled muscle movements).
• Tetrabenazine may also be used for purposes not listed in this medicine guide.
• You must not use this medicine if you are allergic to tetrabenazine, or if you have:
· severe or untreated depression;
· suicidal thoughts;
· liver malady; or
· past or gift breast cancer.
• Do not use tetrabenazine if you have taken reserpine within the past 20 days, or if you have used an MAO inhibitor within the past 14 days. Examples of MAO inhibitors include furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate).
• To create certain you can safely take tetrabenazine, speak your doctor if you have any of these another conditions:
· heart malady or last history of heart attack;
· a private or family history of "Long QT syndrome"; or
· a history of depression or suicidal thoughts or actions.
• You may feel depressed or have thoughts about suicide when you first start taking this medicine. Speak your doctor if you have worsening depression or suicidal thoughts while taking tetrabenazine.
• Your family or another caregivers must also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits while you are taking tetrabenazine.
• FDA pregnancy category C. It is not known whether tetrabenazine will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.
• It is not known whether tetrabenazine passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are taking tetrabenazine.
• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.
• Your doctor may occasionally change your doze to create certain you get the excellent results.
• Call your doctor if your chorea symptoms do not improve, or if they get worse while taking tetrabenazine.
• You may need frequent eye exams while you are taking tetrabenazine. Follow your doctor's instructions.
• Store at room temperature away from moisture and heat.
• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Overdose symptoms may include some of the serious side effects listed in this medicine guide.
• Tetrabenazine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
• Drinking alcohol can magnify determined side effects of tetrabenazine.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Stop using tetrabenazine and call your doctor at once if you have a serious side effect such as:
· extreme drowsiness;
· mood or behavior changes, thoughts about suicide or hurting yourself;
· feeling restless, agitated, or hyperactive (mentally or physically);
· tremor (uncontrolled shaking), restless muscle movements in your eyes, tongue, jaw, or neck;
· trouble swallowing;
· problems with balance;
· dizziness, fainting, quick or pounding heartbeat;
· very stiff (rigid) muscles, tall fever, sweating, confusion, quick or uneven heartbeats, feeling like you might pass out;
· muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine; or
· urinating smaller than normal or not at all, swelling, weight gain, feeling short of breath.
• Smaller serious side effects may include:
· sleep problems (insomnia);
· feeling anxious or irritable;
· mild drowsiness, weary feeling;
· mild nausea;
· breast swelling or discharge; or
· cool symptoms such as stuffy nose, sneezing, sore throat.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Speak your doctor about all another medications you use, especially:
· arsenic trioxide (Trisenox);
· droperidol (Inapsine);
· celecoxib (Celebrex);
· cimetidine (Tagamet);
· darifenacin (Enablex);
· ropinirole (Requip);
· terbinafine (Lamisil);
· ADHD medications (Adderall, Ritalin, Strattera);
· an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), levofloxacin (Levaquin), moxifloxacin (Avelox), or pentamidine (NebuPent, Pentam);
· an antidepressant such as amitriptyline (Elavil), amoxapine (Asendin), bupropion (Wellbutrin, Zyban), clomipramine (Anafranil), desipramine (Norpramin), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), imipramine (Tofranil), paroxetine (Paxil), sertraline (Zoloft);
· anti-malaria medication;
· cancer medications such as gefitinib (Iressa), imatinib (Gleevec), or nilotinib (Tasigna);
· a heart rhythm medication;
· HIV or AIDS medication such as delavirdine (Rescriptor) or ritonavir (Norvir);
· medication to treat or prevent nausea and vomiting, such as dolasetron (Anzemet), metoclopramide (Reglan), ondansetron (Zofran), or promethazine (Phenergan, Promacot);
· medicines to treat Parkinson's malady, restless leg syndrome, or pituitary gland tumor (prolactinoma);
· medication to treat psychiatric disorders, such as aripiprazole (Abilify), chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), olanzapine (Zyprexa), perphenazine (Trilafon), risperidone (Risperdal), thioridazine (Mellaril), ziprasidone (Geodon), and others;
· migraine headache medication such as sumatriptan (Imitrex) or zolmitriptan (Zomig); or
· a narcotic such as levomethadyl (Orlaam), methadone (Methadose, Diskets, Dolophine) or propoxyphene (Darvon, Darvocet).
• This list is not complete and another drugs may interact with tetrabenazine. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.
• Your pharmacist can provide more information about tetrabenazine.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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