TERBINAFINE

(ter BIN na feen) Brand: LamISIL

What is the most significant information I must know about terbinafine?

• Till using terbinafine, speak your doctor if you have liver or kidney malady, or an autoimmune mess such as lupus or psoriasis.

• Take this medicine for the full predesigned length of time. Your symptoms may improve till the infection is completely cleared. Skipping doses may also magnify your risk of further infection that is resistant to antibiotics. Terbinafine will not treat a viral infection such as the general cool or flu.

• Some people taking terbinafine have developed severe liver hurt leading to liver transplant or death. It is not clear whether terbinafine actually caused the liver hurt in these patients. In most cases, the patient had a serious medical condition till taking terbinafine.

• Call your doctor at once if you have symptoms of liver damage, such as nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). These events can occur whether or not you have ever had liver problems before.

• To be certain this medication is not causing deleterious effects, your blood may need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.

• It may take different months for your nails to return to their usual appearance after your treatment with terbinafine.

What is terbinafine?

• Terbinafine is an antifungal antibiotic.

• Terbinafine is used to treat infections caused by fungus that affect the fingernails or toenails. Terbinafine oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old.

• Terbinafine may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking terbinafine?

• You must not use this medicine if you are allergic to terbinafine.

• To create certain you can safely take terbinafine, speak your doctor if you have any of these another conditions:

· liver disease;

· kidney malady;

· a history of depression; or

· an autoimmune mess such as lupus or psoriasis.

• FDA pregnancy category B. This medicine is not expected to be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• Terbinafine can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take terbinafine?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Take the terbinafine tablet with a full glass (8 ounces) of water.

• Terbinafine granules must be sprinkled into a spoonful of pudding or mashed potatoes (do not mix with applesauce, fruit juice, or another acidic foods). Swallow this mixture right away without chewing. Do not save the mixture for later use.

• The terbinafine granule mixture must be taken with a meal.

• Terbinafine is generally taken for 6 to 12 weeks.

• To be certain this medication is not causing deleterious effects, your blood may need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.

• It may take different months for your nails to return to their usual appearance after your treatment with terbinafine.

• Store at room temperature away from moisture, heat, and light.

• Hold the terbinafine oral granules in their sealed packet before you are ready to use.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include dizziness, stomach pain, nausea, vomiting, skin rash, or urinating more than usual.

What must I avoid while taking terbinafine?

• Avoid coffee, tea, cola, energy drinks or another sources of caffeine while taking this medicine.

• Avoid exposure to sunlight or tanning beds. Terbinafine can create you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

What are the possible side effects of terbinafine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop taking terbinafine and call your doctor at once if you have a serious side effect such as:

· fever, chills, body aches, flu symptoms, sores in your mouth and throat;

· joint pain or swelling, swollen glands, patchy skin color, or a butterfly-shaped skin rash over your cheeks and nose;

· changes in mood or behavior;

· hearing problems;

· weight loss due to taste changes;

· raised, silvery flaking of the skin; or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• Smaller serious side effects may include:

· upset stomach, gas, diarrhea, mild nausea or stomach pain;

· headache, dizziness or spinning sensation;

· mild skin rash or itching; or

· unusual or unpleasant taste in your mouth.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect terbinafine?

• Till taking terbinafine, speak your doctor if you are taking any of the next medicines:

· cimetidine (Tagamet, Tagamet HB);

· cyclosporine (Gengraf, Neoral, Sandimmune);

· rifampin (Rifater, Rifadin, Rimactane, Rifamate);

· other antifungal medication, such as fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig), or voriconazole (Vfend);

· a blood thinner such as warfarin (Coumadin, Jantoven);

· a heart rhythm medicine such as amiodarone (Cordarone, Pacerone), propafenone (Rythmol) or flecainide (Tambocor);

· an "SSRI" antidepressant such as fluoxetine (Prozac), fluvoxamine (Luvox), or paroxetine (Paxil);

· a tricyclic antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), desipramine (Norpramin), imipramine (Janimine, Tofranil), and others;

· an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate); or

· a beta-blocker such as betaxolol (Kerlone), carvedilol (Coreg), labetalol (Normodyne), metoprolol (Dutoprol, Lopressor, Toprol), pindolol (Visken), propranolol (Inderal), or timolol (Blocadren).

• This list is not complete and another drugs may interact with terbinafine. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about terbinafine.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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