MOXIFLOXACIN

(moxi FLOX a sin) Brand: Avelox

What is the most significant information I must know about moxifloxacin?

• You must not use this medicine if you have a history of myasthenia gravis, or if you are allergic to moxifloxacin or similar antibiotics such as ciprofloxacin (Cipro), gemifloxacin (Factive), levofloxacin (Levaquin), ofloxacin (Floxin), norfloxacin (Noroxin), and others.

• Till taking moxifloxacin, speak your doctor if you have a heart rhythm mess, kidney or liver malady, joint problems, a history of seizures, low levels of potassium in your blood (hypokalemia), muscle weakness or trouble breathing, a private or family history of Long QT syndrome, or if you have ever had an allergic reaction to an antibiotic.

• Avoid taking antacids, vitamin or mineral supplements, sucralfate (Carafate), or didanosine (Videx) powder or chewable tablets within 8 hours till or 4 hours after you take moxifloxacin. These another medicines can create moxifloxacin many smaller effective when taken at the same time.

• Taking moxifloxacin can create your skin more sensitive to sunlight. Avoid exposure to sunlight, sun lamps, or tanning beds.

• Moxifloxacin may reason swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. These effects may be more likely to occur if you are over 60, if you take steroid medicine, or if you have had a kidney, heart, or lung transplant. Stop taking moxifloxacin and call your doctor at once if you have sudden pain, swelling, tenderness, stiffness, or movement problems in any of your joints. Rest the joint before you receive medical care or instructions.

• Do not share this medicine with other face (especially a child), even if they have the same symptoms you do.

What is moxifloxacin?

• Moxifloxacin is an antibiotic in a group of drugs called fluoroquinolones (flor-o-KWIN-o-lones). Moxifloxacin fights bacteria in the body.

• Moxifloxacin is used to treat various types of bacterial infections.

• Moxifloxacin may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking moxifloxacin?

• To create certain you can safely take moxifloxacin, speak your doctor if you have any of these another conditions:

· heart rhythm mess, especially if you take quinidine (Quin-G), disopyramide (Norpace), bretylium (Bretylol), procainamide (Pronestyl, Procan SR), amiodarone (Cordarone, Pacerone), or sotalol (Betapace);

· a history of allergic reaction to an antibiotic;

· joint problems;

· kidney or liver malady, cirrhosis;

· epilepsy or a history of seizures;

· muscle weakness or trouble breathing;

· low levels of potassium in your blood (hypokalemia); or

· a private or family history of "Long QT syndrome."

• FDA pregnancy category C. It is not known whether moxifloxacin will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• It is not known whether moxifloxacin passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are using moxifloxacin.

• Do not share this medicine with other face (especially a child), even if they have the same symptoms you do.

How must I take moxifloxacin?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Take moxifloxacin with a full glass of water (8 ounces). Drink different extra glasses of fluid every day while you are taking moxifloxacin.

• Moxifloxacin may be taken with or without food, but take it at the same time every day.

• Take this medicine for the full predesigned length of time. Your symptoms may improve till the infection is completely cleared. Skipping doses may also magnify your risk of further infection that is resistant to antibiotics. Moxifloxacin will not treat a viral infection such as the general cool or flu.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include tremors, nausea, vomiting, diarrhea, and seizures (convulsions).

What must I avoid while taking moxifloxacin?

• You may be taking determined another medicines that must not be taken at the same time as moxifloxacin. Avoid taking the next medicines within 8 hours till or 4 hours after you take moxifloxacin. These another medicines can create moxifloxacin many smaller effective when taken at the same time:

· antacids that contain magnesium or aluminum (such as Maalox, Mylanta, or Rolaids);

· the ulcer medication sucralfate (Carafate);

· didanosine (Videx) powder or chewable tablets; or

· vitamin or mineral supplements that contain iron or zinc.

• Avoid exposure to sunlight or tanning beds. Moxifloxacin can create you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Call your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun.

• Antibiotic medicines can reason diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking moxifloxacin and call your doctor. Do not use anti-diarrhea medication unless your doctor tells you to.

• Moxifloxacin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

What are the possible side effects of moxifloxacin?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Stop using moxifloxacin and call your doctor at once if you have a serious side effect such as:

· severe dizziness, fainting, quick or pounding heartbeats;

· sudden pain, snapping or popping sound, bruising, swelling, tenderness, stiffness, or loss of movement in any of your joints;

· diarrhea that is watery or bloody;

· confusion, hallucinations, depression, insomnia or nightmares, unusual thoughts or behavior, feeling light-headed;

· seizure (convulsions);

· severe headache, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes;

· pale or yellowed skin, dark colored urine, fever, weakness;

· urinating smaller than normal or not at all;

· light bruising or bleeding;

· numbness, tingling, or unusual pain anywhere in your body;

· the first sign of any skin rash, no matter how mild; or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• Smaller serious side effects may include:

· nausea, mild diarrhea;

· headache, dizziness;

· blurred vision;

· feeling nervous, anxious, or agitated;

· mild skin itching.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect moxifloxacin?

• Speak your doctor about all another medicines you use, especially:

· a blood thinner such as warfarin (Coumadin, Jantoven);

· an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), levofloxacin (Levaquin), or pentamidine (NebuPent, Pentam);

· an antidepressant such as amitriptylline (Elavil, Vanatrip, Limbitrol), clomipramine (Anafranil), or desipramine (Norpramin);

· anti-malaria medications such as chloroquine (Aralen) or mefloquine (Lariam);

· medication to prevent or treat nausea and vomiting such as dolasetron (Anzemet), droperidol (Inapsine), or ondansetron (Zofran);

· medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon);

· migraine headache medication such as sumatriptan (Imitrex, Treximet) or zolmitriptan (Zomig);

· narcotic medicine such as methadone (Methadose, Diskets, Dolophine);

· an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others; or

· steroid medicine (prednisone and others).

• This list is not complete and another drugs may interact with moxifloxacin. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about moxifloxacin.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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