PENTAMIDINE

(pen TAM e deen) Brand: Nebupent, Pentam 300

What is the most significant information I must know about pentamidine?

Pentamidine may affect blood sugar levels. Contact your doctor if you experience any low blood sugar symptoms including

· heighten appetite;

· headache;

· chills, pale skin, shakes, cool sweats; or

· anxiety.

Pentamidine may affect blood sugar levels. Contact your doctor if you experience any tall blood sugar symptoms including

· heighten thirst;

· loss of appetite;

· magnify in amount or frequency or urination;

· fruity smelling breath; or

· drowsiness.

• Your doctor may want you to have regular blood, heart function, and blood sugar evaluations during treatment with pentamidine to monitor progress and side effects.

What is pentamidine?

Pentamidine is a type of antibiotic that fights protozoa in the body.

Pentamidine is used to prevent and treat serious infections such as Pneumocystis pneumonia.

Pentamidine may also be used for purposes another than those listed in this medicine guide.

What must I discuss with my healthcare provider till taking pentamidine?

• Till taking this medicine, speak your doctor if you have:

· diabetes;

· heart problems

· blood pressure or circulation problems;

· kidney disease;

· pancreatitis;

· asthma;

· last radiation therapy or treatment with chemotherapy;

· a history of dehydration; or

· particular dietary restrictions.

• You may not be able to take pentamidine, or you may require a dosage adjustment or particular monitoring during treatment if you have any of the conditions listed above.

Pentamidine may affect blood sugar levels. Contact your doctor if you experience any low blood sugar symptoms including

· heighten appetite;

· headache;

· chills, pale skin, shakes, cool sweats; or

· anxiety.

Pentamidine may affect blood sugar levels. Contact your doctor if you experience any tall blood sugar symptoms including

· heighten thirst;

· loss of appetite;

· magnify in amount or frequency or urination;

· fruity smelling breath; or

· drowsiness.

• Your doctor may want you to have regular blood, heart function, and blood sugar evaluations during treatment with pentamidine to monitor progress and side effects.

• Conversation to your doctor if you develop an infection of any kind.

Pentamidine is in the FDA pregnancy category C. This means that it is not known whether pentamidine will harm an unborn child. Do not take this medicine without first talking to your doctor if you are pregnant.

• It is not known whether pentamidine passes into breast milk. Do not take this medicine without first talking to your doctor if you are breast-feeding a baby.

How must I take pentamidine?

• Injectable pentamidine can be administered as an injection into a muscle or by slow infusion. The injection must be administered in a clinical setting where a healthcare provider can monitor blood pressure another vital signs and where an abnormal situation can be handled properly.

• Your healthcare provider will store injectable pentamidine as directed by the manufacturer.

Pentamidine for inhalation may be administered via the Respigard II nebulizer as part of a house health regimen by a nurse, respiratory therapist or another healthcare practitioner.

• Store the prepared solution for inhalation at room temperature, away from easy. The solution must be used within 48 hours and any unused portion must be thrown away.

What happens if I miss a dose?

• Since the medicine will be administered by a healthcare provider, missing a doze must not occur. If you have any questions contact your doctor.

What happens if I overdose?

• If an overdose of pentamidine is suspected, search abnormal medical attention or contact your healthcare provider immediately.

Pentamidine must be administered in a clinical setting where a healthcare provider can monitor vital signs (blood pressure, heart rates) and where an abnormal situation can be handled immediately.

What must I avoid while taking pentamidine?

• Speak your doctor if you drink alcohol or caffeine drinks regularly, if you are a smoker or if you use illegal drugs. These factors can affect the way pentamidine works in your body.

What are the possible side effects of pentamidine?

• Side effects with pentamidine are not general. Serious side effects include:

· an allergic reaction (shortness of breath; closing of the throat; hives; swelling of the lips, person, or tongue; rash; or fainting);

· blurred vision;

· chest pain or irregular heart beat;

· difficulty breathing;

· dizziness, confusion, fainting spells or overweening tiredness;

· drastic appetite changes;

· pain or irritation at the injection site;

· mouth ulcers or irritations;

· severe stomach pain;

· bleeding or bruising;

· severe headache;

· chills;

· heighten thirst; or

· seizures.

• Another, smaller serious side effects may be more likely to occur. Conversation to your doctor if you experience

· taste changes;

· diarrhea; or

· nausea or vomiting.

• Side effects another than those listed here may also occur. Conversation to your doctor about any side effect that seems unusual or that is especially bothersome. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect pentamidine?

• Till taking pentamidine, speak your doctor if you are taking any of the next medicines:

· azathioprine (Imuran);

· carbamazepine (Tegretol, Epitol, Carbatrol);

· antibiotics;

· anti-inflammatory drugs (ibuprofen (Advil), naproxen (Aleve), others)

· cisplatin (Platinol)

· didanosine (Videx)

· zidovudine (Retrovir)

· birth control pills;

· ganciclovir (Cytovene)

· blood pressure medications;

· medicine for diabetes;

· valproic acid (Depakote);

· medicine for mental problems; or

· metoclopramide (Reglan).

• You may not be able to take pentamidine, or you may require a dosage adjustment or particular monitoring during treatment if you are taking any of the medicines listed above.

• Drugs another than those listed here may also interact with pentamidine. Conversation to your doctor and pharmacist till taking any prescription or over-the-counter medicines including vitamins, minerals, and herbal commodity. .

Where can I get more information?

• Your pharmacist has additional information about pentamidine written for health professionals that you may read.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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