SERTRALINE

(SER tra leen) Brand: Zoloft

What is the most significant information I must know about sertraline?

• You must not use sertraline if you also take pimozide, or if you are being treated with methylene blue injection.

• Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using sertraline. Your family or another caregivers must also be alert to changes in your mood or symptoms.

• Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

• Do not give sertraline to anyone younger than 18 years old without the advice of a doctor. Sertraline is FDA-approved for children with obsessive-compulsive mess (OCD). It is not authorized for treating depression in children.

What is sertraline?

• Sertraline is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Sertraline affects chemicals in the brain that may become unbalanced and reason depression, panic, anxiety, or obsessive-compulsive symptoms.

• Sertraline is used to treat depression, obsessive-compulsive mess, panic mess, anxiety disorders, post-traumatic stress mess (PTSD), and premenstrual dysphoric mess (PMDD).

• Sertraline may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking sertraline?

• You must not use sertraline if you are allergic to it, if you also take pimozide, or if you are being treated with methylene blue injection.

• Do not use sertraline if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. After you stop taking sertraline, you should wait at least 14 days till you start taking an MAOI.

• To create certain sertraline is safety for you, speak your doctor if you have:

· liver or kidney disease;

· seizures or epilepsy;

· a bleeding or blood clotting disorder;

· bipolar mess (manic depression); or

· a history of drug abuse or suicidal thoughts.

• FDA pregnancy category C. Taking an SSRI antidepressant during pregnancy may reason serious lung problems or another complications in the child. However, you may have a relapse of depression if you stop taking your antidepressant. Speak your doctor right away if you become pregnant while taking sertraline. Do not start or stop taking this medication during pregnancy without your doctor's advice.

• It is not known whether sertraline passes into breast milk or if it could harm a nursing child. Speak your doctor if you are breast-feeding a baby.

How must I take sertraline?

• Follow all directions on your prescription label. Your doctor may occasionally change your doze to create certain you get the excellent results. Do not take this medication in larger or less amounts or for longer than recommended.

• Sertraline may be taken with or without food. Try to take the medication at the same time every day.

• The liquid form of sertraline should be diluted till you take it. To be certain you get the correct doze, measure the liquid with the medication dropper provided. Mix the doze with 4 ounces (one-half cup) of water, ginger ale, lemon/lime soda, lemonade, or orange juice. Do not use any another liquids to dilute the medication. Stir this mixture and drink all of it right away. To create certain you get the entire doze, add a few more water to the same glass, swirl gently and drink right away.

• This medication can reason you to have a false positive drug screening test. If you provide a urine sample for drug screening, speak the laboratory staff that you are taking sertraline.

• It may take up to 4 weeks till your symptoms improve. Hold using the medicine as directed and speak your doctor if your symptoms do not improve.

• Do not stop using sertraline suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using citalopram.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while taking sertraline?

• Ask your doctor till taking a nonsteroidal anti-inflammatory drug (NSAID) for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. Using an NSAID with sertraline may reason you to bruise or bleed easily.

• Drinking alcohol can magnify determined side effects of sertraline.

• Do not take the liquid form of sertraline if you are taking disulfiram (Antabuse). Liquid sertraline may contain alcohol and you could have a severe reaction to the disulfiram.

• This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

What are the possible side effects of sertraline?

• Get abnormal medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have:

· very stiff (rigid) muscles, tall fever, sweating, confusion, quick or uneven heartbeats, feeling like you might pass out;

· agitation, hallucinations, fever, overactive reflexes, tremors;

· nausea, vomiting, diarrhea, loss of appetite, feeling unsteady, loss of coordination; or

· headache, trouble concentrating, memory problems, weakness, fainting, seizure, shallow breathing or breathing that stops.

• General side effects may include:

· drowsiness, dizziness, weary feeling;

· mild nausea, stomach pain, upset stomach, constipation;

· dry mouth;

· changes in appetite or weight;

· sleep problems (insomnia); or

· decreased sex drive, impotence, or difficulty having an orgasm.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect sertraline?

• Taking sertraline with another drugs that create you sleepy or slow your breathing can magnify these effects. Ask your doctor till taking sertraline with a sleeping pill, narcotic pain medication, muscle relaxer, or medication for anxiety or seizures.

• Speak your doctor about all medicines you use, and those you start or stop using during your treatment with sertraline, especially:

· any another antidepressant;

· buspirone;

· cimetidine;

· digitoxin;

· lithium;

· St. John's wort;

· tryptophan (sometimes called L-tryptophan);

· warfarin, Coumadin;

· cough medication that contains dextromethorphan;

· heart or blood pressure medication--flecainide, metoprolol, propafenone, propranolol, and others;

· migraine headache medicines--sumatriptan, zolmitriptan, and others;

· pain medication--fentanyl, tramadol; or

· seizure medication--divalproex, phenytoin.

• This list is not complete. Another drugs may interact with sertraline, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.

Where can I get more information?

• Your pharmacist can provide more information about sertraline.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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