DELAVIRDINE

(de la VIR deen) Brand: Rescriptor

What is the most significant information I must know about delavirdine?

• There are much another drugs that can reason serious or life threatening medical problems if you take them together with delavirdine. Speak your doctor about all another medicines you use, especially: a sedative, cholesterol-lowering medicine, seizure medicine, tuberculosis medicine, or migraine headache medicine.

• Do not start using a new medicine without telling your doctor. Hold a list with you of all the medicines you use and show this list to any doctor or another healthcare provider who treats you.

• HIV/AIDS is generally treated with a combination of various drugs. To excellent treat your condition, use all of your medications as directed by your doctor. Do not change your doses or medicine schedule without advice from your doctor. Each face with HIV or AIDS must stay under the care of a doctor.

• Avoid having unprotected sex or sharing needles, razors, or toothbrushes. Taking this medicine will not prevent you from passing HIV to another people. Conversation with your doctor about safety methods of preventing HIV transmission during sex. Sharing drug or medication needles is never safety, even for a healthy person.

What is delavirdine?

• Delavirdine is an antiviral medicine that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.

• Delavirdine is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Delavirdine is not a cure for HIV or AIDS.

• Delavirdine may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking delavirdine?

• You must not use this medicine if you are allergic to delavirdine, or if you are using any of the next drugs:

· cisapride (Propulsid);

· pimozide (Orap);

· St. John's wort;

· alprazolam (Xanax), midazolam (Versed) or triazolam (Halcion);

· carbamazepine (Carbatrol, Equetro, Tegretol), phenytoin (Dilantin) or phenobarbital (Solfoton);

· lovastatin (Advicor, Altoprev, Mevacor) or simvastatin (Zocor, Simcor, Vytorin, Juvisync);

· rifabutin (Mycobutin) or rifampin (Rifadin, Rifater, Rifamate, Rimactane); or

· ergot medication such as ergotamine (Ergomar, Cafergot, Migergot), dihydroergotamine (D.H.E. 45, Migranal), ergonovine (Ergotrate), or methylergonovine (Methergine).

• Using any of these medicines while you are taking delavirdine can reason serious medical problems or death.

• To create certain delavirdine is safety for you, speak your doctor if you have any of these another conditions:

· liver disease;

· tall cholesterol or triglycerides;

· low stomach acid manufacture; or

· if you have ever taken efavirenz (Sustiva), etravirine (Intelence), nevirapine (Viramune), or rilpivirine (Edurant) and they were not effective in treating your condition.

• FDA pregnancy category C. Speak your doctor if you are pregnant or plan to become pregnant while using this medicine. HIV can be passed to your child if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.

• Women with HIV or AIDS must not breast feed a child. Even if your child is born without HIV, the virus may be passed to the child in your breast milk.

How must I take delavirdine?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Do not take delavirdine as your only HIV medicine. HIV/AIDS is generally treated with a combination of various drugs. Your malady may become resistant to delavirdine if you do not take it in combination with another HIV medicines your doctor has prescribed.

• This medicine comes with patient instructions for safety and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

• Delavirdine can be taken with or without food. If you have a condition of decreased stomach acid, your doctor may recommend taking delavirdine with an acidic beverage such as orange or cranberry juice.

• The 100-milligram delavirdine tablets may be dissolved in water to create swallowing easier. Seat 4 tablets into at least 3 ounces (just under 1/3 cup) of water. Allow the liquid stand for a little minutes, then stir to let the tablets to disperse evenly in the liquid. Drink this mixture right away. To create certain you get the entire doze, add a few more water to the same glass, swirl gently and drink right away.

• The 200-milligram delavirdine tablets should be swallowed whole. Do not crush, chew, or disperse the tablets in water.

• Use delavirdine regularly to get the most benefit. Get your prescription refilled till you run out of medication completely.

• To excellent treat your condition, use all medications as directed by your doctor. Read the medicine manual or patient instructions provided with every medicine. Do not change your doses or medicine schedule without your doctor's advice. Each face with HIV or AIDS must stay under the care of a doctor.

• You may need regular medical trials to be certain this medicine is not causing deleterious effects. Visit your doctor regularly.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while taking delavirdine?

• Avoid taking an antacid within 1 hour till or after you take delavirdine. Some antacids can create it harder for your body to absorb delavirdine.

What are the possible side effects of delavirdine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have any of these serious side effects:

· signs of an infection such as fever, chills, night sweats, sore throat, flu symptoms, weakness, light bruising or unusual bleeding, loss of appetite, mouth sores;

· rapid heart course, tremors, sleep problems (insomnia), feeling anxious or irritable;

· severe diarrhea, unexplained weight loss, menstrual changes, impotence, loss of interest in sex;

· swelling in your neck or throat (enlarged thyroid);

· weakness or prickly feeling in your fingers or toes;

· problems with balance or eye movement, trouble speaking or swallowing;

· severe lower back pain, loss of bladder or bowel control;

· muscle weakness, weary feeling, joint or muscle pain, feeling short of breath; or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• Smaller serious side effects may include:

· mild itching or rash;

· headache, nausea;

· cool symptoms such as stuffy nose, sneezing, sore throat; or

· changes in the shape or location of body thick (especially in your arms, legs, person, neck, breasts, and waist).

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect delavirdine?

• Speak your doctor about all another medicines you use, especially:

· methadone (Methadose, Dolophine);

· sildenafil (Viagra, Revatio);

· ADHD medicine such as Adderall;

· an antibiotic such as clarithromycin (Biaxin) or rifapentine (Priftin);

· an antidepressant such as nefazodone or trazodone (Desyrel);

· antifungal medicine such as itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), or voriconazole (Vfend);

· atorvastatin (Lipitor, Caduet) or fluvastatin (Lescol);

· a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal);

· a blood thinner such as warfarin (Coumadin, Jantoven);

· heart or blood pressure medication such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide), diltiazem (Cardizem, Cartia, Dilacor, Diltia, Diltzac, Taztia, Tiazac), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan, Tarka), and others;

· heart rhythm medication such as amiodarone (Cordarone), flecainide (Tambocor), or propafenone (Rythmol), or quinidine (Quin-G);

· the hepatitis C medications boceprevir (Victrelis) or telaprevir (Incivek);

· HIV/AIDS medicine such as didanosine (Videx), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, Kaletra), saquinavir (Invirase);

· medication to treat or prevent organ transplant rejection;

· steroid medication such as dexamethasone (Cortastat, Dexasone, Solurex, DexPak) or fluticasone (Advair, Flovent, Flonase); or

· stomach medications such as Axid, Pepcid, Prevacid, Prilosec, Tagamet, or Zantac.

• This list is not complete and there are much another medicines that can interact with delavirdine. Speak your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start using a new medicine without telling your doctor. Hold a list with you of all the medicines you use and show this list to any doctor or another healthcare provider who treats you.

Where can I get more information?

• Your pharmacist can provide more information about delavirdine.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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