CELECOXIB (ORAL)

(SEL e KOX ib) Brand: CeleBREX

What is the most significant information I must know about celecoxib?

• This medication may reason life-threatening heart or circulation problems such as heart onslaught or stroke, especially if you use it long term. Do not use celecoxib just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

• Get abnormal medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

• This medication may also reason serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking celecoxib, especially in older adults.

• Call your doctor at once if you have symptoms of stomach bleeding such as black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.

• Avoid drinking alcohol. It may magnify your risk of stomach bleeding.

• Ask a doctor or pharmacist till using any another cool, allergy, or pain medication. Medicines similar to celecoxib are contained in much combination medicines. Check the label to see if a medication contains an NSAID (non-steroidal anti-inflammatory drug) such as aspirin, ibuprofen, ketoprofen, or naproxen.

What is celecoxib?

• Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). Celecoxib works by reducing hormones that reason inflammation and pain in the body.

• Celecoxib is used to treat pain or inflammation caused by much conditions such as arthritis, ankylosing spondylitis, and menstrual pain. Celecoxib is also used in the treatment of hereditary polyps in the colon

• Celecoxib may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking celecoxib?

• Do not use celecoxib just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

• This medication may reason life-threatening heart or circulation problems such as heart onslaught or stroke, especially if you use it long term.

• You must not use this medicine if you are allergic to celecoxib, or if you have a history of allergic reaction to aspirin, sulfa drugs, or another NSAIDs.

• To create certain you can safely take celecoxib, speak your doctor if you have any of these another conditions:

· a history of heart onslaught, stroke, or blood clot;

· heart malady, congestive heart failure, tall blood pressure;

· a history of stomach ulcers or bleeding;

· liver or kidney disease,

· a seizure mess such as epilepsy;

· asthma;

· polyps in your nose; or

· a bleeding or blood clotting disorder.

• FDA pregnancy category D. Taking celecoxib during the recent 3 months of pregnancy may harm the unborn baby. Speak your doctor if you are pregnant or plan to become pregnant while using celecoxib.

• Celecoxib passes into breast milk and may affect a nursing child. Do not take celecoxib without first talking to your doctor if you are breast-feeding a baby.

• Do not give this medication to a baby younger than 2 years old without the advice of a doctor.

How must I take celecoxib?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Take celecoxib with food or milk to lessen stomach upset.

• You may open the celecoxib capsule and sprinkle the medication into a spoonful of applesauce to create swallowing easier. Swallow right away without chewing. Discard the empty capsule. If you do not take the mixture right away, hold it in the refrigerator and take it within 6 hours.

• If you use this medicine long-term, your blood will need to be tested often. Visit your doctor regularly.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Since celecoxib is taken as needed, you may not be on a dosing schedule. If you are taking the medicine regularly, take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include nausea, vomiting, stomach pain, drowsiness, black or bloody stools, coughing up blood, shallow breathing, fainting, or coma.

What must I avoid while taking celecoxib?

• Avoid drinking alcohol. It may magnify your risk of stomach bleeding.

• Avoid taking celecoxib together with another NSAIDs such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn, Naprelan, Treximet), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), mefenamic acid (Ponstel), meloxicam (Mobic), nabumetone (Relafen), or piroxicam (Feldene).

• Ask a doctor or pharmacist till using any another cool, allergy, or pain medication. Medicines similar to celecoxib are contained in much combination medicines. Taking determined commodity together can reason you to get too many of a determined type of drug Check the label to see if a medication contains an NSAID (non-steroidal anti-inflammatory drug) such as aspirin, ibuprofen, ketoprofen, or naproxen.

• Avoid exposure to sunlight or tanning beds. Celecoxib can create you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

What are the possible side effects of celecoxib?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using celecoxib and call your doctor at once if you have a serious side effect such as:

· chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;

· black, bloody, or tarry stools;

· coughing up blood or vomit that looks like coffee grounds;

· swelling or rapid weight gain;

· urinating smaller than normal or not at all;

· nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

· skin rash, bruising, severe tingling, numbness, pain, muscle weakness; or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• Smaller serious side effects may include:

· upset stomach, diarrhea, bloating, gas;

· dizziness, nervousness, headache;

· runny or stuffy nose, sore throat; or

· mild skin rash.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect celecoxib?

• Ask your doctor till using an antidepressant such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft). Taking any of these medicines with an NSAID may reason you to bruise or bleed easily.

• Speak your doctor about all another medicines you use, especially:

· a blood thinner such as warfarin (Coumadin, Jantoven);

· a diuretic (water pill) such as furosemide (Lasix);

· fluconazole (Diflucan);

· lithium (Eskalith, Lithobid);

· a heart or blood pressure medicine such as candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro, Avalide), losartan (Cozaar, Hyzaar), valsartan (Diovan), telmisartan (Micardis), or olmesartan (Benicar); or

· an ACE inhibitor such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others.

• This list is not complete and another drugs may interact with celecoxib. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about celecoxib.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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