ZIPRASIDONE

(zi PRAY si done) Brand: Geodon

What is the most significant information I must know about ziprasidone?

• Ziprasidone is not for use in psychotic conditions related to dementia. Ziprasidone may reason heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

• You must not use this medication if you have a private or family history of Long QT syndrome, if you have recently had a heart onslaught, or if you have uncontrolled heart failure.

• Some medicines can reason unwanted or dangerous effects when used with ziprasidone, and must not be used at the same time. Speak every of your health care providers about all medicines you use now and any medication you start or stop using.

• Stop taking ziprasidone and call your doctor right away if you have a headache with chest pain, severe dizziness, and a quick or pounding heartbeat. These could be signs of a serious heart rhythm problem.

What is ziprasidone?

• Ziprasidone is an antipsychotic medicine. It works by changing the effects of chemicals in the brain.

• Ziprasidone is used to treat schizophrenia and the manic symptoms of bipolar mess (manic depression) in adults and children who are at least 10 years old.

• Ziprasidone may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking ziprasidone?

• Ziprasidone is not for use in psychotic conditions related to dementia. Ziprasidone may reason heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

• You must not use this medication if you are allergic to ziprasidone, or if you have:

· a private or family history of "Long QT syndrome";

· history of last heart onslaught; or

· uncontrolled or untreated heart failure.

• Ziprasidone must never be taken together with any of the next drugs, or a life-threatening heart rhythm mess could occur:

· arsenic trioxide, fluconazole, methadone, tacrolimus, tizanidine;

· an antibiotic--azithromycin, ciprofloxacin, clarithromycin, erythromycin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, pentamidine, trazodone, trimipramine; HIV or AIDS medication--lopinavir, saquinavir;

· anti-malaria medication--chloroquine, mefloquine, quinine; medicine to prevent or treat nausea and vomiting--dolasetron, droperidol, granisetron, ondansetron.

· an antidepressant--amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, maprotiline, nortriptyline; medicine to treat a psychiatric disorder--chlorpromazine, clozapine, fluphenazine, haloperidol, perphenazine, pimozide, prochlorperazine, promethazine, quetiapine, risperidone, thioridazine, trazodone, trifluoperazine; or

· cancer medicine--epirubicin, daunorubicin, doxorubicin, idarubicin, tamoxifen, toremifene; heart rhythm medicine--amiodarone, dofetilide, disopyramide, flecainide, ibutilide, procainamide, propafenone, quinidine, sotalol.

• To create certain ziprasidone is safety for you, speak your doctor if you have:

· a heart rhythm disorder;

· a history of heart onslaught or stroke;

· a history of bone marrow or blood cell disorder;

· a history of breast cancer;

· low blood levels of potassium or magnesium;

· diabetes (ziprasidone may raise your blood sugar);

· seizures or epilepsy;

· a history of suicidal thoughts;

· Parkinson's malady, Alzheimer's;

· trouble swallowing;

· liver malady; or

· kidney disease.

• Ziprasidone may reason you to have tall blood sugar (hyperglycemia). Conversation to your doctor if you have any signs of hyperglycemia such as heighten thirst or urination, overweening famine, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking ziprasidone.

• FDA pregnancy category C. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• Taking antipsychotic medicine during the recent 3 months of pregnancy may reason problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or another problems if you stop taking your medication during pregnancy. If you become pregnant while taking ziprasidone, do not stop taking it without your doctor's advice.

• It is not known whether ziprasidone passes into breast milk or if it could harm a nursing child. You must not breast-feed while using this medicine.

• Older adults may be more likely to have side effects from this medicine.

How must I take ziprasidone?

• Follow all directions on your prescription label. Do not take this medication in larger or less amounts or for longer than recommended.

• This medicine comes with patient instructions for safety and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

• While using ziprasidone, you may need frequent blood trials at your doctor's office. Your kidney or liver function may also need to be checked.

• Take this medication with food.

• Use ziprasidone regularly to get the most benefit. Get your prescription refilled till you run out of medication completely.

• It may take different weeks till your symptoms improve. Hold using the medicine as directed and speak your doctor if your symptoms do not improve.

• Store at room temperature away from moisture, easy, and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while taking ziprasidone?

• While you are taking ziprasidone, you may be more sensitive to temperature extremes such as very hot or cool conditions. Avoid getting too cool, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercice. It is easier to become dangerously overheated and dehydrated while you are taking ziprasidone.

• Ziprasidone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

• Avoid drinking alcohol. It can magnify some of the side effects of ziprasidone.

What are the possible side effects of ziprasidone?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using ziprasidone and call your doctor at once if you have:

· dizziness, feeling light-headed, fainting, quick or pounding heartbeat;

· fever, stiff muscles, confusion, sweating, quick or uneven heartbeats;

· chills, body aches, flu symptoms;

· white patches or sores internal your mouth or on your lips;

· tremor (uncontrolled shaking), restless muscle movements in your eyes, tongue, jaw, or neck;

· agitation, hostility, confusion;

· heighten thirst or urination, weakness, extreme famine; or

· penis erection that is painful or lasts 4 hours or longer.

• General side effects may include:

· mild skin rash;

· anxiety, headache, depressed mood;

· dizziness, drowsiness;

· muscle pain or twitching;

· nausea, vomiting, loss of appetite;

· runny or stuffy nose, cough, sore throat; or

· weight gain.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect ziprasidone?

• Taking ziprasidone with another drugs that create you sleepy or slow your breathing can worsen these effects. Ask your doctor till taking ziprasidone with a sleeping pill, narcotic pain medication, muscle relaxer, or medication for anxiety, depression, or seizures.

• Many drugs can interact with ziprasidone. Not all possible interactions are listed here. Speak your doctor about all your medications and any you start or stop using during treatment with ziprasidone. This includes prescription and over-the-counter medicines, vitamins, and herbal commodity.

Where can I get more information?

• Your pharmacist can provide more information about ziprasidone.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.