ARSENIC TRIOXIDE

(AR sen ik trye OX ide) Brand: Trisenox

What is the most significant information I must know about arsenic trioxide?

Arsenic trioxide can reason a serious and sometimes fatal complication by changing the way your immune system works. Call your doctor at once if you have any signs of this condition, including fever, swelling, weight gain, pain when you breathe, rapid heart course, feeling short of breath, or feeling like you might pass out.

Arsenic trioxide can also have deleterious effects on your heart rhythm. This effect is heighten when you also use determined another drugs. Speak your doctor about all medicines you use, and those you start or stop using during your treatment with arsenic trioxide.

• Get abnormal medical help if you have a headache with chest pain and severe dizziness, and quick or pounding heartbeats.

What is arsenic trioxide?

Arsenic trioxide is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Arsenic trioxide is used to treat a cancer of the blood and bone marrow called acute promyelocytic (pro-MYE-loe-SIT-ik) leukemia, or APL.

Arsenic trioxide may also be used for another purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking arsenic trioxide?

• You must not use arsenic trioxide if you are allergic to it.

• To create certain arsenic trioxide is safety for you, speak your doctor if you have:

· a history of heart disease;

· a heart rhythm mess or history of Long QT syndrome;

· an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);

· kidney malady; or

· liver disease.

• FDA pregnancy category D. Do not use arsenic trioxide if you are pregnant. It could harm the unborn child. Use effective birth control, and speak your doctor if you become pregnant during treatment.

Arsenic trioxide can pass into breast milk and may harm a nursing child. You must not breast-feed while using this medicine.

How is arsenic trioxide given?

Arsenic trioxide is injected into a vein through an IV. A healthcare provider will give you this injection.

• While using arsenic trioxide, you may need frequent blood trials at your doctor's office. Your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG).

You should stay under the care of a doctor while you are using arsenic trioxide. Do not miss any follow-up appointments.

What happens if I miss a dose?

• Call your doctor for instructions if you miss an appointment for your arsenic trioxide injection.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while receiving arsenic trioxide?

• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.

Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.

What are the possible side effects of arsenic trioxide?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

Arsenic trioxide can reason a serious and sometimes fatal complication by changing the way your immune system works. Call your doctor at once if you have any signs of this condition, including:

· fever, weight gain, feeling weak or tired;

· swelling in your ankles or feet;

· cough, pain when you breathe, rapid heart course, feeling short of breath; or

· feeling like you might pass out.

• Also call your doctor right away if you have:

· pale skin, light bruising or bleeding;

· cough, sore throat;

· low potassium (confusion, uneven heart course, extreme thirst, heighten urination, leg discomfort, muscle weakness or limp feeling); or

· tall blood sugar (increased thirst, heighten urination, famine, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss).

• General side effects may include:

· stomach pain, nausea, vomiting;

· constipation, diarrhea;

· headache, dizziness, anxiety, numbness or tingly feeling;

· joint or muscle pain, weary feeling, trouble sleeping; or

· mild itching or rash.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect arsenic trioxide?

Arsenic trioxide can have deleterious effects on your heart rhythm. This effect is heighten when you also use determined another drugs. Speak your doctor about all medicines you use, and those you start or stop using during your treatment with arsenic trioxide, especially:

· amphotericin B;

· methadone;

· tacrolimus;

· vandetanib;

· an antibiotic--azithromycin, clarithromycin, erythromycin, levofloxacin, moxifloxacin, pentamidine;

· an antidepressant--amitriptyline, citalopram, clomipramine, desipramine;

· anti-malaria medication--chloroquine, halofantrine, mefloquine;

· a diuretic or "water pill";

· heart rhythm medicine--amiodarone, dofetilide, disopyramide, dronedarone, flecainide, ibutilide, procainamide, propafenone, quinidine, sotalol;

· medication to prevent or treat nausea and vomiting--dolasetron, droperidol, ondansetron;

· medication to treat a psychiatric disorder--chlorpromazine, clozapine, haloperidol, mesoridazine, pimozide, thioridazine, ziprasidone; or

· migraine headache medicine--sumatriptan, zolmitriptan.

• This list is not complete. Another drugs may interact with arsenic trioxide, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.

Where can I get more information?

• Your doctor or pharmacist can provide more information about arsenic trioxide.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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© 2006-2024 medpill.info Last Updated On: 03/20/2024 (0.1)
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