AMOXAPINE

(a MOX a peen) Brand: Asendin

What is the most significant information I must know about amoxapine?

• Never take amoxapine in larger amounts, or for longer than recommended by your doctor. Tall doses or long-term use of amoxapine can reason a serious movement mess that may not be reversible. Symptoms of this mess include tremors or another uncontrollable muscle movements.

• You must not use amoxapine if you are allergic to it, or if you have recently had a heart attack.

• Do not use amoxapine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the recent 14 days. A dangerous drug interaction could occur, leading to serious side effects.

• Avoid drinking alcohol. It can reason dangerous side effects when taken together with amoxapine.

• You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

• Message any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

What is amoxapine?

• Amoxapine is a tricyclic antidepressants. Amoxapine affects chemicals in the brain that may become unbalanced.

• Amoxapine is used to treat symptoms of depression, anxiety, or agitation.

• Amoxapine may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking amoxapine?

• You must not use amoxapine if you are allergic to it, or if you have recently had a heart attack.

• To create certain amoxapine is safety for you, speak your doctor if you have any of these conditions:

· heart disease;

· a history of heart onslaught, stroke, or seizures;

· kidney disease;

· schizophrenia or another mental illness;

· diabetes (amoxapine may raise or lower blood sugar);

· bipolar mess (manic depression);

· glaucoma; or

· problems with urination.

• You may have thoughts about suicide while taking an antidepressant, especially if you are younger than 24 years old. Speak your doctor if you have worsening depression or suicidal thoughts during the first different weeks of treatment, or whenever your doze is changed.

• Your family or another caregivers must also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

• FDA pregnancy category C. It is not known whether amoxapine will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• Amoxapine can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

• Older adults may be more likely to have side effects from this medicine.

• Do not give this medicine to anyone under 18 years old without the advice of a doctor.

How must I take amoxapine?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Your doctor may occasionally change your doze to create certain you get the excellent results.

• It may take up to 3 weeks till your symptoms improve. Hold using the medicine as directed and speak your doctor if your symptoms do not improve after 3 weeks of treatment.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amoxapine can be fatal.

• Overdose symptoms may include seizure (convulsions) or coma.

What must I avoid while taking amoxapine?

• Avoid drinking alcohol. It can reason dangerous side effects when taken together with amoxapine.

• Grapefruit and grapefruit juice may interact with amoxapine and lead to unwanted side effects. Discuss the use of grapefruit commodity with your doctor.

• This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

What are the possible side effects of amoxapine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Stop taking amoxapine and call your doctor at once if you have a serious side effect such as:

· very stiff (rigid) muscles, tall fever, sweating, confusion, tremors, feeling like you might pass out;

· pounding heartbeats or fluttering in your chest;

· chest pain or hard feeling, pain spreading to the hand or shoulder, nausea, sweating, common ill feeling;

· sudden numbness or weakness, especially on one side of the body; or

· sudden severe headache, confusion, problems with vision, speech, or balance.

• Smaller serious side effects may include:

· drowsiness, dizziness, headache, weary feeling;

· feeling restless or nervous;

· dry mouth, blurred vision;

· mild nausea, constipation;

· heighten appetite, weight changes;

· heighten sweating; or

· sleep problems (insomnia), night mares.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect amoxapine?

• Cool or allergy medication, sedatives, narcotic pain medication, sleeping pills, muscle relaxers, and seizure medicine can add to sleepiness caused by amoxapine. Speak your doctor if you regularly use any of these medicines, or any another antidepressants.

• Till taking amoxapine, tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft).

• Speak your doctor about all another medicines you use, especially:

· bupropion (Wellbutrin, Zyban);

· cimetidine (Tagamet);

· duloxetine (Cymbalta);

· St. John's wort;

· terbinafine (Lamisil); or

· heart rhythm medications such as flecainide (Tambocor), propafenone (Rythmol), or quinidine (Quin-G).

• This list is not complete and another drugs may interact with amoxapine. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about amoxapine.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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