(DAW noe ROO bi sin) Brand: Cerubidine
• Daunorubicin may reason dangerous effects on your heart. Call your doctor at once if you have chest pain, shortness of breath (even with mild exertion), swelling, or rapid weight gain.
• Daunorubicin can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).
• Daunorubicin is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
• Daunorubicin is used in the treatment of leukemia (blood cancer).
• Daunorubicin may also be used for purposes not listed in this medicine guide.
• You must not use daunorubicin if you are allergic to it.
• To create certain daunorubicin is safety for you, speak your doctor if you have:
· heart malady;
· kidney disease;
· liver disease;
· a weak immune system (caused by malady or by using determined medicines); or
· if you have ever been treated with doxorubicin, epirubicin, idarubicin, mitoxantrone, or liposomal daunorubicin (Daunoxome).
• Using daunorubicin may magnify your risk of developing another types of leukemia. Ask your doctor about your specific risk.
• FDA pregnancy category D. Do not use daunorubicin if you are pregnant. It could harm the unborn child. Use effective birth control, and speak your doctor if you become pregnant during treatment.
• It is not known whether daunorubicin passes into breast milk or if it could harm a nursing child. You must not breast-feed while using this medicine.
• Daunorubicin is injected into a vein through an IV. A healthcare provider will give you this injection.
• Till you receive every doze of daunorubicin, your heart function may need to be checked with an electrocardiograph or ECG (sometimes called an EKG). Your kidney and liver function may also need to be checked.
• Speak your caregivers if you feel any burning, pain, or swelling near the IV needle when daunorubicin is injected.
• Skin accidentally exposed to daunorubicin must be rinsed thoroughly with soap and warm water.
• Daunorubicin can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.
• Call your doctor for instructions if you miss an appointment for your daunorubicin injection.
• Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
• Avoid being around people who are sick or have infections. Speak your doctor at once if you develop signs of infection.
• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.
• Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have:
· chest pain, shortness of breath (even with mild exertion), swelling, rapid weight gain;
· fever, chills, body aches, flu symptoms, sores in your mouth and throat;
· light bruising, unusual bleeding (nose, mouth, vagina, or rectum);
· nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
· pain, burning, irritation, or skin changes where the injection was given.
• General side effects may include:
· mild nausea, vomiting, diarrhea, stomach pain;
· temporary hair loss, mild itching or rash; or
· red colored urine for 1 or 2 days next a dose.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Speak your doctor about all medicines you use, and those you start or stop using during your treatment with daunorubicin, especially:
· acetaminophen (Tylenol);
· methotrexate;
· an antibiotic, antifungal medication, sulfa drug, or tuberculosis medicine;
· birth control pills or hormone replacement therapy;
· cholesterol-lowering medications--Crestor, Lipitor, Pravachol, Simcor, Vytorin, Zocor, and others;
· drugs that weaken the immune system, such as cancer medication, steroids, and medicines to prevent organ transplant rejection;
· gout or arthritis medications (including gold injections);
· heart or blood pressure medication;
· HIV/AIDS medications;
· medicines to treat mental illness;
· an NSAID (non-steroidal anti-inflammatory drug)--ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, others; or
· seizure medication--carbamazepine, phenytoin, and others.
• This list is not complete. Another drugs may interact with daunorubicin, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.
• Your doctor or pharmacist can provide more information about daunorubicin.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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