MAPROTILINE

(ma PROE ti leen) Brand: Ludiomil

What is the most significant information I must know about maprotiline?

• You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

• Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

• Do not use maprotiline if you have a seizure mess, or if you have used an MAO inhibitor within the past 14 days. Serious, life-threatening side effects can occur if you take maprotiline till the MAO inhibitor has cleared from your body.

• Till taking maprotiline, speak your doctor if you have liver or kidney malady, seizures, heart malady, a thyroid mess, if you receive electroshock therapy, or if you have a history of heart onslaught, stroke, drug abuse, or suicidal thoughts.

• It may take up to 3 weeks of using this medication till your symptoms improve. For excellent results, hold using the medicine as directed. Conversation with your doctor if your symptoms do not improve after 3 weeks of treatment.

• Avoid drinking alcohol. It can magnify some of the side effects of maprotiline.

• Maprotiline can reason side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What is maprotiline?

• Maprotiline is an antidepressant. Maprotiline affects chemicals in the brain that may become unbalanced and reason depression.

• Maprotiline is used to treat major depressive mess, depressive neurosis, and manic-depression illness.

• Maprotiline may also be used for purposes another than those listed in this medicine guide.

What must I discuss with my healthcare provider till taking maprotiline?

• You must not take this medicine if you are allergic to maprotiline, or if you have a seizure disorder.

• You may have thoughts about suicide while taking an antidepressant, especially if you are younger than 24 years old. Speak your doctor if you have worsening depression or suicidal thoughts during the first different weeks of treatment, or whenever your doze is changed.

• Your family or another caregivers must also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

• Do not use maprotiline if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take maprotiline till the MAO inhibitor has cleared from your body.

• Till taking maprotiline, speak your doctor if you are allergic to any drugs, or if you have:

· liver or kidney disease;

· if you are receiving electroshock therapy;

· seizures or epilepsy;

· a thyroid disorder;

· heart malady, heart rhythm disorder;

· a history of heart onslaught or stroke; or

· a history of drug abuse or suicidal thoughts.

• If you have any of these conditions, you may not be able to use maprotiline, or you may need a dosage adjustment or particular trials during treatment.

• FDA pregnancy category B. This medicine is not expected to be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• Maprotiline can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

• Older adults may be more sensitive to the side effects of this medication.

How must I take maprotiline?

• Take this medicine exactly as predesigned by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

• Take the regular tablet form of maprotiline with water.

• Maprotiline is generally taken once a day at bedtime. Follow your doctor's instructions.

• Store maprotiline at room temperature, away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. If it is nearly time for your following doze, wait before then to take the medication and skip the missed doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medicine.

• Overdose symptoms may include extreme drowsiness, quick heart course, confusion, vomiting, blue lips or fingernails, and seizure (convulsions).

What must I avoid while taking maprotiline?

• Cool or allergy medication, narcotic pain medication, sleeping pills, muscle relaxers, and medication for seizures, depression or anxiety can add to sleepiness caused by maprotiline. Speak your doctor if you need to use any of these another medicines while you are taking maprotiline.

• Avoid drinking alcohol. It can magnify some of the side effects of maprotiline.

• Maprotiline can reason side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What are the possible side effects of maprotiline?

• Get abnormal medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have any of these serious side effects:

· seizure (convulsions);

· quick or pounding heart rate;

· confusion, hallucinations;

· unusual thoughts or behavior; or

· feeling like you might pass out.

• Smaller serious side effects include:

· drowsiness, dizziness;

· loss of balance or coordination;

· numbness or tingling;

· blurred vision;

· ringing in your ears;

· nausea, stomach pain;

· constipation;

· dry mouth; or

· thirst.

• This is not a complete list of side effects and others may occur. Speak your doctor about any unusual or bothersome side effect. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect maprotiline?

• The next drugs can interact with maprotiline. Speak your doctor if you are using any of these:

· guanethidine (Ismelin);

· medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), mesoridazine (Serentil), or thioridazine (Mellaril);

· a sedative such as Valium;

· cimetidine (Tagamet); or

· phenytoin (Dilantin).

• This list is not complete and there may be another drugs that can interact with maprotiline. Speak your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about maprotiline.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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