IDARUBICIN

(EYE da ROO bi sin) Brand: Idamycin PFS

What is the most significant information I must know about idarubicin?

Idarubicin may reason dangerous effects on your heart. Call your doctor at once if you have chest pain, shortness of breath (even with mild exertion), swelling, or rapid weight gain.

• Speak your caregivers if you feel any burning, pain, or swelling near the IV needle when idarubicin is injected. Call your doctor if you have irritation or skin changes where the injection was given.

Idarubicin can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).

What is idarubicin?

Idarubicin is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Idarubicin is used to treat acute myeloid leukemia (AML), a type of blood cancer.

Idarubicin may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till receiving idarubicin?

• Till you are treated with idarubicin, speak your doctor about all another cancer medications and treatments you have received, including radiation.

• You must not receive idarubicin if you are allergic to it.

• To create certain idarubicin is safety for you, speak your doctor if you have:

· kidney disease;

· liver disease;

· heart disease;

· gout;

· weak immune system (caused by malady or by using determined medicines); or

· if you have been treated till with doxorubicin, daunorubicin, epirubicin, idarubicin, or mitoxantrone.

• FDA pregnancy category D. Do not use idarubicin if you are pregnant. It could harm the unborn child. Use effective birth control to avoid pregnancy during your treatment with idarubicin. Follow your doctor's instructions about how long to prevent pregnancy after your treatment ends.

• It is not known whether idarubicin passes into breast milk or if it could harm a nursing child. You must not breast-feed while using this medicine.

How must I use idarubicin?

Idarubicin is injected into a vein through an IV. A healthcare provider will give you this injection.

Idarubicin is generally given together with another cancer medications. You may be given another medications to prevent nausea, vomiting, or infections.

• Speak your caregivers if you feel any burning, pain, or swelling near the IV needle when idarubicin is injected.

• If any of this medicine accidentally gets on your skin, wash it thoroughly with soap and warm water.

Idarubicin can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your kidney and liver function may also need to be tested.

• Your heart function may also need to be checked at your doctor's office using an electrocardiograph or ECG (sometimes called an EKG).

What happens if I miss a dose?

• Call your doctor for instructions if you miss an appointment for your idarubicin injection.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while using idarubicin?

• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.

Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.

• Avoid being around people who are sick or have infections. Speak your doctor at once if you develop signs of infection.

• Avoid activities that may magnify your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

Do not receive a "live" vaccine while using idarubicin, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

What are the possible side effects of idarubicin?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have:

· fever, swollen gums, painful mouth sores, pain when swallowing;

· skin sores, cool or flu symptoms, cough, trouble breathing;

· rectal pain, blood in your stools, diarrhea;

· severe nausea, vomiting, or stomach cramps;

· light bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;

· irritation or skin changes where the injection was given;

· shortness of breath (even with mild exertion), swelling, rapid weight gain;

· change in your mental state, seizure (convulsions);

· joint pain and stiffness; or

· jaundice (yellowing of the skin or eyes).

• General side effects may include:

· mild stomach discomfort;

· numbness or tingling;

· headache; or

· temporary hair loss.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect idarubicin?

• Another drugs may interact with idarubicin, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Speak every of your health care providers about all medicines you use now and any medication you start or stop using.

Where can I get more information?

• Your doctor or pharmacist can provide more information about idarubicin.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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