(EP i ROO bi sin) Brand: Ellence
• You must not use this medicine if you have an untreated or uncontrolled infection, severe liver malady, severe heart problems, or if you have recently had a heart attack.
• Epirubicin may reason dangerous effects on your heart. Call your doctor at once if you have chest pain, shortness of breath (even with mild exertion), swelling, or rapid weight gain.
• Speak your caregivers if you feel any burning, pain, or swelling near the IV needle when epirubicin is injected. Call your doctor if you have irritation or skin changes where the injection was given.
• Epirubicin can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).
• Using epirubicin may magnify your risk of another types of cancer, such as leukemia.
• Epirubicin is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
• Epirubicin is used to treat breast cancer.
• Epirubicin may also be used for purposes not listed in this medicine guide.
• Till you are treated with epirubicin, speak your doctor about all another cancer medications and treatments you have received, including radiation.
• You must not use this medicine if you are allergic to epirubicin or similar medications (Cerubidine, Adriamycin, Idamycin, Novantrone), or if you have:
· an untreated or uncontrolled infection (including mouth sores);
· severe liver disease;
· severe heart problems; or
· if you have recently had a heart attack.
• To create certain epirubicin is safety for you, speak your doctor if you have:
· liver or kidney disease;
· bone marrow suppression;
· heart malady; or
· if you have been treated till with doxorubicin, daunorubicin, epirubicin, idarubicin, or mitoxantrone.
• Using epirubicin may magnify your risk of developing another types of cancer, such as leukemia. Conversation with your doctor about your specific risk.
• FDA pregnancy category D. Do not use epirubicin if you are pregnant. It could harm the unborn child. Speak your doctor if you become pregnant during treatment.
• Use birth control to prevent pregnancy while you are receiving epirubicin, whether you are a man or a woman. Epirubicin use by either parent may reason birth defects.
• It is not known whether epirubicin passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are using epirubicin.
• Epirubicin is injected into a vein through an IV. A healthcare provider will give you this injection.
• Epirubicin is generally given together with another cancer medications. You may be given another medications to prevent nausea, vomiting, or infections.
• Speak your caregivers if you feel any burning, pain, or swelling near the IV needle when epirubicin is injected.
• If any of this medicine accidentally gets on your skin, wash it thoroughly with soap and warm water.
• Epirubicin can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.
• Call your doctor for instructions if you miss an appointment for your epirubicin injection.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.
• Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
• Avoid being around people who are sick or have infections. Speak your doctor at once if you develop signs of infection.
• Avoid activities that may magnify your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
• Do not receive a "live" vaccine while using epirubicin, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Speak your caregivers at once if you have:
· feeling short of breath, even with mild exertion;
· swelling, rapid weight gain (especially in your person and midsection);
· irritation or skin changes where the injection was given;
· nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
· quick, slow, or uneven heartbeats;
· anxiety, sweating, severe shortness of breath, wheezing, gasping for breath;
· chest pain, sudden cough, cough with foamy mucus, rapid breathing, coughing up blood;
· lower back pain, blood in your urine, few or no urinating;
· numbness or tingly feeling near your mouth, weak pulse, overactive reflexes, confusion, fainting;
· muscle weakness, tightness, or contraction;
· fever, chills, body aches, flu symptoms, sores in your mouth and throat; or
· pale skin, light bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin.
• General side effects may include:
· hot flashes, missed menstrual periods;
· temporary hair loss;
· feeling weak or tired;
· mild nausea, diarrhea; or
· eye redness, puffy eyelids.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Much drugs can interact with epirubicin. Not all possible interactions are listed here. Speak your doctor about all your medications and any you start or stop using during treatment with epirubicin, especially:
· acetaminophen (Tylenol);
· auranofin or gold injections to treat arthritis;
· cimetidine;
· an antibiotic or antifungal medication;
· an antidepressant--amitriptyline, doxepin, clomipramine, desipramine, imipramine, nortriptyline;
· birth control pills or hormone replacement therapy;
· cholesterol medications--atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin;
· heart or blood pressure medicine--amlodipine, atenolol, carvedilol, digoxin, diltiazem, enalapril, labetalol, lisinopril, methyldopa, nifedipine, verapamil, and others;
· HIV/AIDS medications;
· NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others;
· another cancer medications, especially docetaxel or paclitaxel; or
· seizure medications--carbamazepine, divalproex, phenobarbital, phenytoin, valproic acid, and others.
• This list is not complete and much another drugs can interact with epirubicin. This includes prescription and over-the-counter medicines, vitamins, and herbal commodity. Give a list of all your medicines to any healthcare provider who treats you.
• Your doctor or pharmacist can provide more information about epirubicin.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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