(RIL pi VIR een) Brand: Edurant
• You must not use rilpivirine if you are allergic to it.
• Some medicines can interact with rilpivirine and must not be used at the same time. Speak every of your health care providers about all medicines you use now and any medication you start or stop using.
• Till you take rilpivirine, speak your doctor if you have liver malady (including hepatitis B or C), kidney malady, a history of depression or mental diseases, or if you have ever taken any HIV medicine in the past.
• Do not take rilpivirine as your only HIV medication. Rilpivirine should be used in combination with another HIV medicines that your doctor has prescribed.
• Call your doctor at once if you have mood changes, anxiety, severe depression, feeling hopeless, or thoughts about suicide or hurting yourself.
• Taking this medicine will not prevent you from passing HIV to another people.
• Rilpivirine is an antiviral medicine that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.
• Rilpivirine is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Rilpivirine is not a cure for HIV or AIDS.
• Do not take rilpivirine as your only HIV medication. Rilpivirine should be used in combination with another HIV medicines that your doctor has prescribed.
• Rilpivirine may also be used for purposes not listed in this medicine guide.
• You must not use rilpivirine if you are allergic to it.
• Some medicines can reason unwanted or dangerous effects when used with rilpivirine. Your doctor may need to change your treatment plan if you use any of the next drugs:
· carbamazepine, oxcarbazepine, phenobarbital, phenytoin;
· rifabutin, rifampin, rifapentine;
· esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole;
· more than one doze of dexamethasone;
· St John's wort; or
· delavirdine, efavirenz, etravirine, nevirapine.
• Using any of these medicines while you are taking rilpivirine can reason serious medical problems or death.
• To create certain rilpivirine is safety for you, speak your doctor if you have:
· liver malady (including hepatitis B or C);
· kidney malady;
· a history of depression or mental diseases; or
· if you have ever taken any HIV medicine in the past.
• FDA pregnancy category B. Rilpivirine is not expected to harm an unborn child, but HIV can be passed to your child if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.
• If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to estimate any effects of rilpivirine on the baby.
• Women with HIV or AIDS must not breast feed a child. Even if your child is born without HIV, the virus may be passed to the child in your breast milk.
• Follow all directions on your prescription label. Do not take this medication in larger or less amounts or for longer than recommended.
• Rilpivirine is generally taken once for day with a meal. Always take the medication with food.
• Use rilpivirine regularly to get the most benefit. Get your prescription refilled till you run out of medication completely.
• While using rilpivirine, you may need frequent blood trials at your doctor's office.
• HIV/AIDS is generally treated with a combination of drugs. Use all medications as directed by your doctor. Read the medicine manual or patient instructions provided with every medicine. Do not change your doses or medicine schedule without your doctor's advice. Each face with HIV or AIDS must stay under the care of a doctor.
• Store at room temperature away from moisture, heat, and light.
• If you are smaller than 12 hours late in taking your medication, take the missed doze with food as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• If you also take an antacid, take it at least 2 hours till or 4 hours after taking rilpivirine. Do not take an antacid and rilpivirine at the same time.
• If you also take didanosine (Videx), take it at least 2 hours till or 4 hours after taking rilpivirine.
• If you also take a stomach acid reducer, take it at least 12 hours till or 4 hours after taking rilpivirine. This includes cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), and ranitidine (Zantac). Do not take rilpivirine and this type of stomach medication at the same time.
• Taking this medicine will not prevent you from passing HIV to another people. Do not have unprotected sex or share razors or toothbrushes. Conversation with your doctor about safety ways to prevent HIV transmission during sex. Sharing drug or medication needles is never safety, even for a healthy person.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have:
· mood changes, anxiety, severe depression, feeling hopeless, thoughts about suicide or hurting yourself;
· fever, chills, cough with yellow or green mucus;
· stabbing chest pain, wheezing, feeling short of breath;
· nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
· severe pain in your upper stomach spreading to your shoulder or back, stomach bloating, vomiting, sweating, fever, chills.
• General side effects may include:
· sleep problems (insomnia), unusual dreams;
· mild nausea, vomiting, stomach pain, diarrhea;
· headache, dizziness;
· mild skin rash;
· weary feeling; or
· changes in the shape or location of body thick (especially in your arms, legs, person, neck, breasts, and waist).
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Much drugs can interact with rilpivirine. Not all possible interactions are listed here. Speak your doctor about all your medications and any you start or stop using during treatment with rilpivirine, especially:
· bosentan;
· conivaptan;
· imatinib;
· methadone;
· tacrolimus;
· arsenic trioxide, vandetanib;
· an antibiotic--azithromycin, clarithromycin, erythromycin, levofloxacin, moxifloxacin, nafcillin, pentamidine, telithromycin;
· an antidepressant--amitriptyline, citalopram, clomipramine, desipramine, nefazodone;
· antifungal medication--itraconazole, ketoconazole, posaconazole, voriconazole;
· anti-malaria medication--chloroquine, halofantrine, mefloquine;
· heart medication--amiodarone, dofetilide, disopyramide, dronedarone, flecainide, ibutilide, nicardipine, procainamide, propafenone, quinidine, sotalol;
· hepatitis C medications--boceprevir, telaprevir;
· HIV/AIDS medication--atazanavir, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir;
· medication to prevent or treat nausea and vomiting--dolasetron, droperidol, ondansetron;
· medication to treat a psychiatric disorder--chlorpromazine, clozapine, haloperidol, mesoridazine, pimozide, thioridazine, ziprasidone;
· migraine headache medicine--sumatriptan, zolmitriptan; or
· seizure medication--fosphenytoin, primidone.
• This list is not complete and there are much another medicines that can interact with rilpivirine, or create it smaller effective. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor. Hold a list of all your medicines and show it to any healthcare provider who treats you.
• Your pharmacist can provide more information about rilpivirine.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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