NEVIRAPINE
(ne VYE ra peen) Brand: Viramune, Viramune XR
What is the most significant information I must know about nevirapine?
• You must not use nevirapine if you have temperate to severe liver malady. Nevirapine must not be used to prevent HIV.
• Your blood will need to be tested often during the first little months you are taking nevirapine. Each face with HIV or AIDS must stay under the care of a doctor.
• Nevirapine can reason severe or fatal liver problems. Stop taking this medication and call your doctor at once if you have any of signs of liver damage: nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).
• Nevirapine may also reason severe or life-threatening skin reactions. Contact your doctor at once if you have fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling. This type of reaction is a medical emergency.
What is nevirapine?
• Nevirapine is an antiviral medicine that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.
• Nevirapine is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Nevirapine will not prevent or cure HIV or AIDS.
• Nevirapine may also be used for purposes not listed in this medicine guide.
What must I discuss with my healthcare provider till taking nevirapine?
• You must not use this medication if you are allergic to nevirapine, or if you have temperate to severe liver malady. Nevirapine must not be used to prevent HIV.
• Some medicines can interact with nevirapine and must not be used at the same time. Your doctor may need to change your treatment plan if you use any of the next drugs:
· atazanavir;
· efavirenz;
· itraconazole;
· ketoconazole;
· rifampin; or
· St. John's wort.
• To create certain you can safely take nevirapine, speak your doctor if you have any of these another conditions:
· skin problems;
· liver malady (or a history of hepatitis or cirrhosis);
· kidney malady (or if you are on dialysis); or
· if you have ever taken delavirdine or efavirenz and they were not effective in treating your condition.
• FDA pregnancy category B. Nevirapine is not expected to be deleterious to an unborn child. However, nevirapine may be more likely to reason liver hurt in a pregnant woman. Speak your doctor if you are pregnant or plan to become pregnant during treatment.
• HIV can be passed to your child if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.
• Nevirapine can create birth control pills smaller effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking nevirapine.
• If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to estimate any effects of nevirapine on the baby.
• Women with HIV or AIDS must not breast-feed a child. Even if your child is born without HIV, the virus may be passed to the child in your breast milk.
• Nevirapine must not be given to a baby younger than 6 years old.
How must I take nevirapine?
• Follow all directions on your prescription label. Do not take this medication in larger or less amounts or for longer than recommended.
• Nevirapine is generally taken only once daily for the first 2 weeks, and then heighten to twice daily. Starting with a low doze can reduce your risk of skin reactions. Follow your doctor's instructions about how often to take the medication.
• If you stop taking nevirapine for longer than 7 days, call your doctor till you start taking the medication again. You may have to start with a lower dose.
• Nevirapine can be taken with or without food. You may also take the medication with milk or a soft drink.
• Do not crush, chew, or interrupt an extended-release tablet. Swallow it intact.
• Shake the oral suspension (liquid) well just till you measure a doze. Measure the liquid with a particular dose-measuring spoon or medication cup. If you do not have a dose-measuring device, ask your pharmacist for one.
• To be certain this medicine is helping your condition, your blood cells and liver function will need to be tested often, especially during the first 6 to 18 weeks of treatment. Visit your doctor regularly.
• Use nevirapine regularly to get the most benefit. Get your prescription refilled till you run out of medication completely.
• Do not take nevirapine as your only HIV medicine. HIV/AIDS is generally treated with a combination of various drugs. Your malady may become resistant to nevirapine if you do not take it in combination with another HIV medicines your doctor has prescribed.
• Use all medications as directed by your doctor. Read the medicine manual or patient instructions provided with every medicine. Do not change your doses or medicine schedule without your doctor's advice. Each face with HIV or AIDS must stay under the care of a doctor.
• Store at room temperature away from moisture and heat.
What happens if I miss a dose?
• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed doze.
• If you have not taken nevirapine for 7 days in a row, call your doctor till you start taking the medication again.
What happens if I overdose?
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
What must I avoid while taking nevirapine?
• Avoid drinking alcohol. It may magnify your risk of liver damage.
• Taking this medicine will not prevent you from passing HIV to another people. Do not have unprotected sex or share razors or toothbrushes. Conversation with your doctor about safety ways to prevent HIV transmission during sex. Sharing drug or medication needles is never safety, even for a healthy person.
What are the possible side effects of nevirapine?
• Get abnormal medical help if you have any of these signs of an allergic reaction: weary feeling, joint or muscle pain, muscle weakness, skin rash, bruising, severe tingling, numbness, mouth sores, trouble breathing, or swelling of your person, lips, tongue, or throat.
• Nevirapine can reason life-threatening effects on the liver. Call your doctor at once if you have any of these liver symptoms while taking nevirapine: skin rash, nausea, stomach pain, loss of appetite, low fever, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
• Nevirapine may also reason severe or life-threatening skin reactions. Contact your doctor at once if you have fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling. This type of reaction is a medical emergency.
• Stop using nevirapine and call your doctor at once if you have:
· fever, swollen gums, painful mouth sores, pain when swallowing, skin sores, cool or flu symptoms, cough, trouble breathing;
· any another signs of new infection; or
· the first sign of any skin rash, no matter how mild.
• General side effects may include:
· mild nausea, vomiting, diarrhea, or stomach pain;
· muscle pain;
· headache, weary feeling; or
· changes in the shape or location of body thick (especially in your arms, legs, person, neck, breasts, and waist).
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
What another drugs will affect nevirapine?
• Many drugs can interact with nevirapine, or create it smaller effective. Not all possible interactions are listed here. Speak your doctor about all your medications and any you start or stop using during treatment with nevirapine, especially:
· maraviroc;
· a blood thinner (warfarin, Coumadin);
· an antibiotic such as clarithromycin or rifabutin;
· antifungal medication such as fluconazole or voriconazole;
· ergot medication such as ergotamine, dihydroergotamine, ergonovine, or methylergonovine;
· heart or blood pressure medications such as amiodarone, diltiazem, disopyramide, felodipine, nifedipine, verapamil, and others;
· medicine to prevent organ transplant rejection;
· another HIV medicines such as darunavir, fosamprenavir, nelfinavir, indinavir, ritonavir, or saquinavir; or
· seizure medicine such as carbamazepine, clonazepam, or ethosuximide.
• This list is not complete and much another drugs can interact with nevirapine. This includes prescription and over-the-counter medicines, vitamins, and herbal commodity. Give a list of all your medicines to any healthcare provider who treats you.
Where can I get more information?
• Your pharmacist can provide more information about nevirapine.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.