KETOCONAZOLE

(KEE toe KON a zole) Brand: Nizoral

What is the most significant information I must know about ketoconazole?

• You must not use this medicine if you are allergic to ketoconazole, or if you are also taking triazolam (Halcion).

• Till taking ketoconazole, speak your doctor if you have liver malady, kidney malady, a heart rhythm mess, decreased stomach acid (achlorhydria), or a history of "Long QT syndrome."

• Take this medicine for the entire length of time predesigned by your doctor. Your symptoms may get better till the infection is completely treated. Ketoconazole will not treat a viral infection such as the general cool or flu.

• Avoid taking antacids or stomach acid reducers (Tagamet, Pepcid, Axid, Zantac, and others) for at least 2 hours after you have taken your doze of ketoconazole. These medications can create it harder for the ketoconazole tablet to dissolve in your stomach.

• Avoid drinking alcohol. It may reason unpleasant side effects while you are taking ketoconazole.

What is ketoconazole?

• Ketoconazole is an antifungal antibiotic.

• Ketoconazole is used to treat infections caused by fungus, which can invade any part of the body including the mouth, throat, esophagus, lungs, bladder, or skin.

• Ketoconazole may also be used for another purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking ketoconazole?

• You must not use this medicine if you are allergic to ketoconazole, or if you are also taking triazolam (Halcion).

• If you have any of these another conditions, you may need a doze adjustment or particular trials to safely take ketoconazole:

· decreased stomach acid (achlorhydria);

· liver disease;

· kidney disease;

· a heart rhythm mess; or

· a private or family history of "Long QT syndrome."

• FDA pregnancy category C. It is not known whether ketoconazole is deleterious to an unborn child. Till you take this medicine, speak your doctor if you are pregnant or plan to become pregnant during treatment.

• Ketoconazole may pass into breast milk and could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take ketoconazole?

• Take this medicine exactly as it was predesigned for you. Do not take the medicine in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

• Ketoconazole works excellent if you take it with food.

• To be certain this medicine is not causing deleterious effects, your liver function may need to be checked with blood trials on a regular basis. Do not miss any scheduled appointments.

• Store ketoconazole at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. If it is nearly time for your following doze, skip the missed doze and take the medication at your following regularly scheduled time. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medication. Symptoms of a ketoconazole overdose are not known.

What must I avoid while taking ketoconazole?

• Avoid drinking alcohol. It may reason unpleasant side effects while you are taking ketoconazole.

What are the possible side effects of ketoconazole?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have any of these serious side effects:

· dizziness, fainting, quick or pounding heartbeat;

· light bruising or bleeding, unusual weakness;

· numbness or tingly feeling;

· severe depression, confusion, or thoughts of hurting yourself; or

· nausea, stomach pain, low fever, loss of appetite, weakness, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

• Smaller serious side effects may include:

· mild nausea, vomiting, or stomach pain;

· mild itching or skin rash;

· headache;

· dizziness;

· breast swelling; or

· impotence or loss of interest in sex.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect ketoconazole?

• Much drugs can interact with ketoconazole. Adown is just a partial list. Speak your doctor if you are using:

· acetaminophen (Tylenol);

· cyclosporine (Gengraf, Sandimmune, Neoral);

· clopidogrel (Plavix);

· digoxin (digitalis, Lanoxin);

· tacrolimus ((Prograf);

· loratadine (Alavert, Claritin, Tavist ND);

· methylprednisolone (Medrol);

· phenytoin (Dilantin);

· rifampin (Rifadin, Rifater, Rifamate, Rimactane);

· diabetes medicine you take by mouth;

· a sedative such as midazolam (Versed);

· a blood thinner such as warfarin (Coumadin);

· cancer medications;

· birth control pills or hormone replacement therapy;

· methotrexate (Rheumatrex, Trexall);

· cholesterol medications such as niacin (Advicor), atorvastatin (Lipitor), lovastatin (Altocor, Mevacor), simvastatin (Zocor), and others; or

· medications to treat HIV or AIDS.

• This list is not complete and there are much another drugs that can interact with ketoconazole. Speak your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start using a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about ketoconazole.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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