RABEPRAZOLE

(ra BEP ra zole) Brand: AcipHex

What is the most significant information I must know about rabeprazole?

• Heartburn is often confused with the first symptoms of a heart onslaught. Search abnormal medical attention if you have chest pain or hard feeling, pain spreading to the hand or shoulder, nausea, sweating, and a common ill feeling.

• You must not use this medicine if you are allergic to rabeprazole or to similar medicines such as lansoprazole (Prevacid), esomeprazole (Nexium), omeprazole (Prilosec, Zegerid), or pantoprazole (Protonix).

• Rabeprazole is not for immediate relief of heartburn symptoms.

• Some conditions are treated with a combination of rabeprazole and antibiotics. Use all medications as directed by your doctor. Read the medicine manual or patient instructions provided with every medicine. Do not change your doses or medicine schedule without your doctor's advice.

• Take this medicine for the full predesigned length of time. Your symptoms may improve till the infection is completely cleared.

What is rabeprazole?

• Rabeprazole is in a group of drugs called proton exhaust inhibitors. Rabeprazole decreases the amount of acid produced in the stomach.

• Rabeprazole is used to treat symptoms of gastroesophageal reflux malady (GERD) and another conditions inclusion overweening stomach acid such as Zollinger-Ellison syndrome. Rabeprazole is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

• Rabeprazole may also be given with an antibiotic to prevent gastric ulcer caused by infection with helicobacter pylori (H. pylori).

• Rabeprazole is not for immediate relief of heartburn symptoms.

• Rabeprazole may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking rabeprazole?

• To create certain you can safely take rabeprazole, speak your doctor if you have severe liver malady or low magnesium levels in your blood.

• Taking a proton exhaust inhibitor such as rabeprazole may magnify your risk of bone fracture in the hip, wrist, or spine. This effect has occurred mostly in people who have taken the medicine long term or at tall doses, and in those who are age 50 and older. It is not clear whether rabeprazole is the actual reason of an heighten risk of fracture. Till you take this medicine, speak your doctor if you have osteoporosis or osteopenia (low bone mineral density).

• FDA pregnancy category B. This medicine is not expected to be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether rabeprazole passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take rabeprazole?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Rabeprazole is generally given for 4 to 8 weeks only. Your doctor may recommend a second rate of treatment if you need additional healing time.

• When treating H. pylori infection, rabeprazole may be needed for only 7 days. Follow your doctor's instructions.

• Take this medication with a full glass (8 ounces) of water.

• Rabeprazole may be taken with or without food.

• Do not crush, interrupt, or chew a rabeprazole tablet. Swallow it intact. Breaking the pill may reason too many of the drug to be released at one time.

• Take this medicine for the full predesigned length of time. Your symptoms may improve till the infection is completely cleared.

• Call your doctor if your symptoms do not improve or if they get worse while you are taking this medicine.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while taking rabeprazole?

• This medicine can reason diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking rabeprazole and call your doctor. Do not use anti-diarrhea medication unless your doctor tells you to.

What are the possible side effects of rabeprazole?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using rabeprazole and call your doctor at once if you have symptoms of low magnesium such as:

· dizziness, confusion;

· quick or uneven heart rate;

· jerking muscle movements;

· feeling jittery;

· diarrhea that is watery or bloody;

· muscle cramps, muscle weakness or limp feeling;

· cough or choking feeling; or

· seizure (convulsions).

• Smaller serious side effects may include:

· headache;

· upset stomach, mild diarrhea;

· insomnia or nervousness; or

· a rash or itching.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect rabeprazole?

• Speak your doctor about all another medicines you use, especially:

· atazanavir (Reyataz);

· a blood thinner such as warfarin (Coumadin, Jantoven);

· digoxin (digitalis, Lanoxin);

· a diuretic (water pill);

· ketoconazole (Nizoral);

· methotrexate (Rheumatrex, Trexall); or

· cyclosporine (Gengraf, Sandimmune, Neoral).

• This list is not complete and another drugs may interact with rabeprazole. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about rabeprazole.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

(40)