ASPIRIN AND OXYCODONE

(AS pir in and ox i KOE done) Brand: Endodan, Percodan, Roxiprin

What is the most significant information I must know about aspirin and oxycodone?

• Aspirin must not be given to a baby or teenager who has a fever, especially if the baby also has flu symptoms or chicken pox. Aspirin can reason a serious and sometimes fatal condition called Reye's syndrome in children.

• You must not take aspirin and oxycodone if you have a bleeding mess, a last history of stomach or intestinal bleeding, if you take a blood thinner, or if you are allergic to aspirin, oxycodone, or an NSAID (non-steroidal anti-inflammatory drug) such as Advil, Motrin, Aleve, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others.

• Do not use aspirin and oxycodone if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the recent 14 days. A dangerous drug interaction could occur, leading to serious side effects.

• Oxycodone may be habit-forming and should be used only by the face for whom it was prescribed. Hold the medicine in a secure seat where others can't get to it.

• Ask a doctor or pharmacist till using any another over-the-counter cool, allergy, or pain medication. Aspirin is contained in much combination medicines. Taking determined commodity together can reason you to get too many aspirin. Check the label to see if a medication contains aspirin.

What is aspirin and oxycodone?

• Aspirin is in a group of drugs called salicylates (sa-LIS-il-ates). It works by reducing substances in the body that reason pain, fever, and inflammation.

• Oxycodone is an opioid pain medicine. An opioid is sometimes called a narcotic.

• The combination of aspirin and oxycodone is used to relieve temperate to severe pain.

• Aspirin and oxycodone may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking aspirin and oxycodone?

• You must not use this medicine if you are allergic to aspirin or oxycodone, or if you have:

· a last history of stomach or intestinal bleeding;

· a bleeding or blood clotting mess such as hemophilia;

· if you are taking a blood thinner such as warfarin (Coumadin, Jantoven); or

· an allergy to an NSAID (non-steroidal anti-inflammatory drug) such as Advil, Motrin, Aleve, Celecoxib, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others.

• To create certain you can safely take aspirin and oxycodone, speak your doctor if you have any of these another conditions:

· stomach or intestinal mess, history of stomach ulcer or bleeding;

· severe constipation, a blockage in your stomach or intestines;

· liver or kidney disease;

· allergies, nasal polyps, asthma or another breathing disorders;

· a heart rhythm mess, low blood pressure;

· enlarged prostate, urination problems;

· underactive thyroid;

· gallbladder disease;

· seizures, or a history of head injury or brain tumor;

· Addison's malady or another adrenal gland disorder;

· curvature of the spine;

· mental diseases, a history of drug or alcohol addiction; or

· if you have been sick with diarrhea.

• Oxycodone may be habit forming and must be used only by the face for whom it was predesigned. Never share this medicine with other face, especially somebody with a history of drug abuse or addiction.

• FDA pregnancy category D. This medicine can reason harm to an unborn child, and breathing problems or addiction/withdrawal symptoms in a newborn. Taking aspirin during late pregnancy may reason bleeding in the mother or the child during delivery. Do not take aspirin and oxycodone during pregnancy unless your doctor has told you to. Use an effective form of birth control, and speak your doctor if you become pregnant during treatment.

• Aspirin and oxycodone can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take aspirin and oxycodone?

• Take exactly as predesigned. Never take aspirin and oxycodone in larger amounts, or for longer than recommended by your doctor. Follow the directions on your prescription label. Speak your doctor if the medication seems to stop working as well in relieving your pain.

• Aspirin and oxycodone may be taken with food if it upsets your stomach.

• If you need surgery, speak the surgeon onward of time that you are using aspirin and oxycodone.

• Do not stop using aspirin and oxycodone suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using aspirin and oxycodone.

• Store at room temperature away from moisture, heat, and easy. After you have stopped using this medicine, flush any unused pills down the toilet.

• Hold track of the amount of medication used from every new bottle. Oxycodone is a drug of abuse and you must be aware if anyone is using your medication improperly or without a prescription.

• Always check your bottle to create certain you have received the correct pills (same brand and type) of medication predesigned by your doctor. Ask the pharmacist if you have any questions about the medication you receive at the pharmacy.

What happens if I miss a dose?

• Since aspirin and oxycodone is taken as needed, you may not be on a dosing schedule. If you are taking the medicine regularly, take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. An overdose of aspirin and oxycodone can be fatal.

• Overdose symptoms may include extreme drowsiness, pinpoint pupils, nausea, vomiting, diarrhea, confusion, ringing in your ears, cool or clammy skin, muscle weakness, fainting, weak pulse, slow heart course, coma, blue lips, shallow breathing, or no breathing.

What must I avoid while taking aspirin and oxycodone?

• This medicine may impair your thinking or reactions. Avoid driving or operating machinery before you know how aspirin and oxycodone will affect you.

• Avoid taking acetaminophen (Tylenol) or an NSAID while you are taking aspirin and oxycodone, unless your doctor tells you to. NSAIDs include ibuprofen (Advil, Motrin), ketorolac (Toradol), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others.

• Avoid drinking alcohol. It may magnify your risk of stomach bleeding while taking aspirin.

What are the possible side effects of aspirin and oxycodone?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have a serious side effect such as:

· severe stomach pain or constipation, vomiting;

· black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;

· weak or shallow breathing, quick or slow heartbeats;

· confusion, hallucinations, feeling like you might pass out;

· light bruising or bleeding;

· seizures; or

· decreased hearing, ringing in your ears.

• Smaller serious side effects may include:

· headache, dizziness, drowsiness;

· constipation, heartburn, upset stomach, bloating, gas, diarrhea; or

· dry mouth.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect aspirin and oxycodone?

• Ask your doctor till using an antidepressant such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Rapiflux, Sarafem, Selfemra, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil, Pexeva), sertraline (Zoloft), trazodone (Desyrel, Oleptro), or vilazodone (Viibryd). Taking any of these medicines with aspirin may reason you to bruise or bleed easily.

• Till using this medicine, speak your doctor if you regularly use another medicines that create you sleepy or could slow your breathing (such as cool or allergy medication, sedatives, narcotic pain medication, sleeping pills, muscle relaxers, and medication for seizures, depression, or anxiety). They can add to sleepiness caused by aspirin and oxycodone.

• Many drugs can interact with aspirin and oxycodone. Adown is just a partial list. Speak your doctor if you are using:

· bupropion (Wellbutrin, Zyban);

· deferasirox (Exjade);

· leflunomide (Arava);

· methotrexate (Rheumatrex, Trexall);

· sirolimus (Rapamune) or tacrolimus (Prograf);

· tenofovir (Viread, Atripla, Complera, Truvada);

· antiviral medicines such as adefovir (Hepsera) or cidofovir (Vistide);

· aspirin or another salicylates including Kaopectate, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others;

· bowel cleansing preparations (Half Lytely, Fleet Prep Kit, Evac-Q-Kwik, GoLytely, Supraprep, and others);

· glaucoma medicine such as acetazolamide (Diamox) or methazolamide (Glauctabs, Neptazane); or

· medicine used to prevent blood clots, such as dalteparin (Fragmin), enoxaparin (Lovenox), fondaparinux (Arixtra), tinzaparin (Innohep), and others.

• This list is not complete and another drugs may interact with aspirin and oxycodone. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about aspirin and oxycodone.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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