(tin ZA pa rin) Brand: Innohep
• You must not use this medicine if you are allergic to tinzaparin, heparin, sulfites, benzyl alcohol, or pork commodity, or if you have active bleeding or a history of low platelet counts after receiving heparin.
• Speak any doctor who treats you that you are using tinzaparin. If you need anesthesia for a medical procedure or surgery, you may need to stop using the medication for a short time.
• Tinzaparin may reason you to bleed more easily, especially if you have: a bleeding mess, hemorrhagic stroke, an infection in the lining of your heart, uncontrolled tall blood pressure, stomach or intestinal bleeding or ulcer, kidney malady, liver failure, amyloidosis (a build-up of determined proteins in tissues and organs of the body), or if you have had last brain, spine, or eye surgery.
• Tinzaparin can reason a very serious blood clot near your brain or spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural), especially if you have a genetic spinal defect, a history of spinal surgery or repeated spinal taps, or if you are using another medications to treat or prevent blood clots. Symptoms of this type of blood clot include numbness, tingling, muscle weakness, or loss of movement.
• Blood clots near the brain or spinal cord may occur during a spinal tap or epidural if you are using tinzaparin with another drugs that can affect blood clotting, including aspirin, non-steroidal anti-inflammatory drugs (NSAIDs) such as Advil or Motrin, and any another medications to treat or prevent blood clots.
• Much another drugs (including some over-the-counter medicines) can magnify your risk of bleeding or life-threatening blood clots, and it is very significant to speak your doctor about all medicines you have recently used.
• Speak your caregivers at once if you have signs of bleeding such as black or bloody stools, coughing up blood, confusion, feeling like you might pass out, or any bleeding that will not stop.
• Tinzaparin is an anticoagulant that helps prevent the formation of blood clots.
• Tinzaparin is used together with warfarin (Coumadin) to treat a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism).
• Tinzaparin may also be used for purposes not listed in this medicine guide.
• You must not use this medicine if you are allergic to tinzaparin, heparin, sulfites, benzyl alcohol, or pork commodity, or if you have:
· active or uncontrolled bleeding; or
· if you have ever had low platelet counts after receiving heparin.
• Tinzaparin may reason you to bleed more easily, especially if you have:
· a bleeding mess that is inherited or caused by disease;
· hemorrhagic stroke;
· an infection of the lining of your heart (also called bacterial endocarditis);
· uncontrolled tall blood pressure;
· stomach or intestinal bleeding or ulcer;
· liver failure;
· kidney malady (especially if you are an older adult);
· last brain, spine, or eye surgery; or
· amyloidosis (a build-up of determined proteins in tissues and organs of the body).
• Tinzaparin can reason a very serious blood clot near your brain or spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could reason long-term paralysis, and may be more likely to occur if you have:
· a genetic spinal defect;
· a history of spinal surgery or repeated spinal taps; or
· if you are using another medications to treat or prevent blood clots.
• To create certain you can safely use tinzaparin, speak your doctor if you have another medical conditions, especially:
· last stomach ulcer; or
· eye problems caused by diabetes.
• FDA pregnancy category B. Tinzaparin is not expected to harm an unborn child. However, some forms of this medicine contain a preservative that may be deleterious to a newborn. Speak your doctor if you are pregnant or plan to become pregnant during treatment.
• It is not known whether tinzaparin passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.
• Use exactly as predesigned by your doctor. Do not use in larger or less amounts or for longer than recommended. Tinzaparin is generally given each day before your bleeding condition improves. Follow the directions on your prescription label.
• Tinzaparin should not be used as a substitute for heparin. These two drugs are manufactured differently and have various dosages.
• Tinzaparin is injected under the skin. You may be shown how to use injections at house. Do not self-inject this medication if you do not fully understand how to give the injection and properly dispose of used needles and syringes.
• You must be sitting or lying down during the injection. Do not inject tinzaparin into a muscle or a vein.
• Use a various seat on your stomach every time you give the injection. Your care provider will show you the excellent places on your body to inject the medicine. Do not inject into the same seat two times in a row.
• Prepare your doze in a syringe only when you are ready to give yourself an injection. Do not use the medicine if it has changed colors or has particles in it. Call your doctor for a new prescription.
• Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Hold this container out of the reach of children and pets.
• Speak any doctor who treats you that you are using tinzaparin. If you need surgery or dental work, speak the surgeon or dentist onward of time that you are using this medication.
• To be certain this medicine is not causing deleterious effects, your blood and your stool (bowel movement) may need to be tested often. Your nerve and muscle function may also need to be tested. Visit your doctor regularly.
• Store at room temperature away from moisture and heat.
• Use the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not use extra medication to create up the missed dose.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Overdose can reason overweening bleeding.
• Avoid activities that may magnify your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Stop using tinzaparin and call your doctor at once if you have a serious side effect such as:
· unusual bleeding (nose, mouth, vagina, or rectum), bleeding from wounds or needle injections, any bleeding that will not stop;
· light bruising, purple or red pinpoint spots under your skin;
· pale skin, feeling light-headed or short of breath, rapid heart course, trouble concentrating;
· black or bloody stools, coughing up blood or vomit that looks like coffee grounds;
· numbness, tingling, or muscle weakness (especially in your legs and feet);
· loss of movement in any part of your body;
· sudden weakness, severe headache, confusion, or problems with speech, vision, or balance;
· chest pain; or
· pain or burning when you urinate.
• Smaller serious side effects may include:
· mild headache, dizziness;
· back pain;
· fever;
· pain, irritation, swelling, or bruising of the skin where the medication was injected;
· nausea, vomiting, stomach pain, gas;
· diarrhea, constipation;
· mild skin rash; or
· sleep problems (insomnia).
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Much another drugs (including some over-the-counter medicines) can magnify your risk of bleeding, or your risk of developing blood clots near the brain or spinal cord during a spinal tap or epidural. It is very significant to speak your doctor about all medicines you have recently used, especially:
· dextran (Gentran, Hyskon);
· abciximab (ReoPro), eptifibatide (Integrilin), ticagrelor (Brilinta), tirofiban (Aggrastat);
· alteplase (Activase), reteplase (Retavase), tenecteplase (TNKase), urokinase (Abbokinase);
· anagrelide (Agrylin), cilostazol (Pletal), clopidogrel (Plavix), dipyridamole (Persantine, Aggrenox), eltrombopag (Promacta), oprelvekin (Neumega), prasugrel (Effient), romiplostim (Nplate), ticagrelor (Brilinta), ticlopidine (Ticlid);
· argatroban (Acova), bivalirudin (Angiomax), dabigatran (Pradaxa), lepirudin (Refludan);
· dalteparin (Fragmin), enoxaparin (Lovenox), fondaparinux (Arixtra), heparin, rivaroxaban (Xarelto), warfarin (Coumadin, Jantoven);
· an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others; or
· salicylates such as aspirin, Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others.
• This list is not complete and another drugs may interact with tinzaparin. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.
• Your doctor or pharmacist can provide more information about tinzaparin.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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