NAPROXEN

(na PROX en) Brand: Aleve, Anaprox, Anaprox-DS, EC-Naprosyn, Leader Naproxen Sodium, Midol Extended Relief, Naprelan 375, Naprosyn

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What is the most significant information I must know about naproxen?

• You must not use naproxen if you have a history of allergic reaction to aspirin or another NSAID (nonsteroidal anti-inflammatory drug).

Naproxen may magnify your risk of heart onslaught or stroke, especially if you use it long term or have heart malady. Do not use this medication just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

Naproxen may also reason stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are taking naproxen.

What is naproxen?

Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). Naproxen works by reducing hormones that reason inflammation and pain in the body.

Naproxen is used to treat pain or inflammation caused by conditions such as arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps.

Naproxen may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking naproxen?

Naproxen may magnify your risk of heart onslaught or stroke, especially if you use it long term or have heart malady. Do not use this medication just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

Naproxen may also reason stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are taking naproxen.

• You must not use naproxen if you are allergic to it, or if you have a history of allergic reaction to aspirin or another NSAIDs.

• Ask a doctor or pharmacist if it is safety for you to take this medication if you have:

· a history of heart onslaught, stroke, or blood clot;

· heart malady, congestive heart failure, tall blood pressure;

· a history of stomach ulcers or bleeding;

· liver or kidney disease;

· asthma;

· polyps in your nose;

· a bleeding or blood clotting mess; or

· if you smoke.

• FDA pregnancy category C. Till using naproxen, speak your doctor if you are pregnant or plan to become pregnant during treatment. Taking naproxen during the recent 3 months of pregnancy may result in birth defects. Do not take naproxen during pregnancy unless your doctor has told you to.

Naproxen can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

• Do not give this medication to a baby younger than 2 years old without medical advice.

How must I take naproxen?

• Use exactly as directed on the label, or as predesigned by your doctor. Do not use in larger or less amounts or for longer than recommended.

• The delayed-release tablet is a slower-acting form of naproxen and must be used only for treating arthritis or ankylosing spondylitis. Follow your doctor's instructions.

• Do not crush, chew, or interrupt an extended-release or enteric-coated tablet. Swallow the pill intact. The extended-release pill is specially made to release medication slowly in the body. The enteric-coated pill has a particular coating to protect your stomach.

• Shake the oral suspension (liquid) well just till you measure a doze. Measure the liquid with a particular dose-measuring spoon or medication cup. If you do not have a dose-measuring device, ask your pharmacist for one.

• If you use this medicine long-term, you may need frequent medical trials at your doctor's office.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Since naproxen is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not use extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while taking naproxen?

• Ask a doctor or pharmacist till using any cool, allergy, or pain medicine. Much medicines accessible over the counter contain aspirin or another medicines similar to naproxen (such as ibuprofen or ketoprofen). Taking determined commodity together can reason you to get too many of this type of medicine. Check the label to see if a medication contains naproxen, aspirin, ibuprofen, or ketoprofen.

• Avoid drinking alcohol. It may magnify your risk of stomach bleeding.

• Avoid exposure to sunlight or tanning beds. Naproxen can create you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

What are the possible side effects of naproxen?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using naproxen and call your doctor at once if you have:

· chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;

· black, bloody, or tarry stools;

· coughing up blood or vomit that looks like coffee grounds;

· swelling or rapid weight gain, few or no urinating;

· nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

· bruising, severe tingling, numbness, pain, muscle weakness;

· fever, headache, neck stiffness, chills, heighten sensitivity to easy, purple spots on the skin, and/or seizure (convulsions) or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• General side effects may include:

· upset stomach, mild heartburn or stomach pain, diarrhea, constipation;

· bloating, gas;

· dizziness, headache, nervousness;

· skin itching or rash;

· blurred vision; or

· ringing in your ears.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect naproxen?

Ask your doctor till using naproxen if you take an antidepressant such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. Taking any of these medicines with an NSAID may reason you to bruise or bleed easily.

• Ask a doctor or pharmacist if it is safety for you to use naproxen if you are also using any of the next drugs:

· a blood thinner (warfarin, Coumadin);

· lithium;

· methotrexate;

· a diuretic or "water pill";

· steroids (prednisone and others);

· aspirin or another NSAIDs--ibuprofen (Advil, Motrin), celecoxib, diclofenac, indomethacin, meloxicam, and others; or

· heart or blood pressure medication--benazepril, candesartan, enalapril, lisinopril, losartan, olmesartan, quinapril, ramipril, telmisartan, valsartan, and others.

• This list is not complete. Another drugs may interact with naproxen, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.

Where can I get more information?

• Your pharmacist can provide more information about naproxen.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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