ADEFOVIR

(a DEF o veer) Brand: Hepsera

What is the most significant information I must know about adefovir?

• This medication may reason a serious condition called lactic acidosis. Get abnormal medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cool feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, quick or uneven heart course, dizziness, or feeling very weak or weary.

• Adefovir can also reason serious kidney problems, especially if you have kidney malady or take determined medications.

• Speak your doctor if you have been exposed to HIV, or if you have untreated HIV or AIDS. Taking medicines to treat chronic hepatitis B can reason HIV infection to become resistant to the standard HIV and AIDS medications. You may need to be tested for HIV till you start taking adefovir.

• You may develop liver symptoms after you stop taking this medication. Your doctor may want to check your liver function for different months after you stop using adefovir.

What is adefovir?

• Adefovir is an antiviral medicine. Adefovir prevents viral cells from multiplying in the body and infecting new liver cells.

• Adefovir is used to treat chronic hepatitis B in people who are 12 years of age or older. Adefovir is not a cure for chronic hepatitis B.

• Adefovir may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking adefovir?

• You must not take adefovir if you are allergic to it.

• Do not take adefovir if you also take Atripla, Complera, Stribild, Truvada, or Viread.

• Some people taking adefovir develop a serious condition called lactic acidosis. This may be more likely in women, in people who are overweight or have liver malady, and in people who have taken HIV/AIDS medicine for a long time. Conversation with your doctor about your risk.

• To create certain adefovir is safety for you, speak your doctor if you have:

· kidney malady; or

· liver disease.

• FDA pregnancy category C. It is not known whether adefovir will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• Your name may need to be listed on an antiviral pregnancy registry when you start using this medication.

• It is not known whether adefovir passes into breast milk or if it could harm a nursing child. You must not breast-feed while using this medicine.

How must I take adefovir?

• Follow all directions on your prescription label. Do not take this medication in larger or less amounts or for longer than recommended.

• Take adefovir with a full glass of water. Adefovir may be taken with or without food.

• Use this medication regularly to get the most benefit. Get your prescription refilled till you run out of medication completely. You must not stop using adefovir without your doctor's advice.

• While using adefovir, you may need frequent blood trials. Your kidney or liver function may also need to be checked. You should stay under the care of a doctor while you are using adefovir. Visit your doctor regularly.

• Store at room temperature away from moisture and heat.

• You may develop liver symptoms after you stop taking this medication. Your doctor may want to check your liver function for different months after you stop using adefovir.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while taking adefovir?

• Taking this medicine will not prevent you from passing hepatitis B to another people. Do not have unprotected sex or share razors or toothbrushes. Conversation with your doctor about safety ways to prevent transmission during sex. Sharing drug or medication needles is never safety, even for a healthy person.

What are the possible side effects of adefovir?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Early symptoms of lactic acidosis may get worse over time and this condition can be fatal. Get abnormal medical help if you have even mild symptoms: muscle pain or weakness, numb or cool feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, quick or uneven heart course, dizziness, or feeling very weak or weary.

• Call your doctor at once if you have:

· few or no urinating;

· swelling, rapid weight gain;

· confusion, loss of appetite, vomiting, pain in your side or lower back; or

· severe stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

• General side effects may include:

· mild stomach pain, diarrhea, gas, indigestion;

· weakness; or

· headache.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect adefovir?

• Adefovir can harm your kidneys. This effect is heighten when you also use determined another medicines, including: antivirals, chemotherapy, injected antibiotics, medication for bowel disorders, medication to prevent organ transplant rejection, and some pain or arthritis medicines (including aspirin, Tylenol, Advil, and Aleve).

• Another drugs may interact with adefovir, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Speak every of your health care providers about all medicines you use now and any medication you start or stop using.

Where can I get more information?

• Your pharmacist can provide more information about adefovir.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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