(fon DAP a rin ux) Brand: Arixtra
• You must not use this medicine if you are allergic to fondaparinux, heparin, or pork commodity, or if you have active bleeding, severe kidney malady, an infection in the lining of your heart, or a low level of platelets in your blood after testing positive for a determined antibody while using fondaparinux.
• Speak any doctor who treats you that you are using fondaparinux. If you need anesthesia for a medical procedure or surgery, you may need to stop using the medication for a short time.
• You must not use fondaparinux to prevent blood clots after surgery if you weigh smaller than 110 pounds (50 kilograms).
• Fondaparinux may reason you to bleed more easily, especially if you have: a bleeding mess, hemorrhagic stroke, eye problems caused by diabetes, uncontrolled tall blood pressure, stomach or intestinal bleeding or ulcer, last brain or spine surgery, last eye surgery, or if you are an older adult who has kidney problems.
• Fondaparinux can reason a very serious blood clot near your brain or spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural), especially if you have a genetic spinal defect, a history of spinal surgery or repeated spinal taps, or if you are using another medications to treat or prevent blood clots. Symptoms of this type of blood clot include numbness, tingling, muscle weakness, or loss of movement.
• Blood clots near the brain or spinal cord may occur during a spinal tap or epidural if you are using fondaparinux with another drugs that can affect blood clotting, including aspirin, non-steroidal anti-inflammatory drugs (NSAIDs) such as Advil or Motrin, and any another medications to treat or prevent blood clots.
• Much another drugs (including some over-the-counter medicines) can magnify your risk of bleeding or life-threatening blood clots, and it is very significant to speak your doctor about all medicines you have recently used.
• Speak your caregivers at once if you have signs of bleeding such as black or bloody stools, coughing up blood, confusion, feeling like you might pass out, or any bleeding that will not stop.
• Fondaparinux is an anticoagulant that helps prevent the formation of blood clots.
• Fondaparinux is used to prevent a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism). A DVT can occur after determined types of surgery.
• Fondaparinux is also used together with warfarin (Coumadin) to treat DVT, including pulmonary embolism.
• Fondaparinux may also be used for purposes not listed in this medicine guide.
• You must not use this medicine if you are allergic to fondaparinux, heparin, or pork commodity, or if you have:
· active or uncontrolled bleeding;
· severe kidney disease;
· an infection in the lining of your heart (also called bacterial endocarditis); or
· a low level of platelets in your blood after testing positive for a determined antibody while using fondaparinux.
• You must not use fondaparinux to prevent blood clots after surgery if you weigh smaller than 110 pounds (50 kilograms).
• Fondaparinux may reason you to bleed more easily, especially if you have:
· a bleeding mess that is inherited or caused by disease;
· hemorrhagic stroke;
· eye problems caused by diabetes;
· uncontrolled tall blood pressure;
· stomach or intestinal bleeding or ulcer;
· last brain, spine, or eye surgery; or
· kidney malady (especially if you are an older adult).
• Fondaparinux can reason a very serious blood clot near your brain or spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could reason long-term paralysis, and may be more likely to occur if you have:
· a genetic spinal defect;
· a history of spinal surgery or repeated spinal taps; or
· if you are using another medications to treat or prevent blood clots.
• FDA pregnancy category B. Fondaparinux is not expected to be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.
• It is not known whether fondaparinux passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.
• Use exactly as predesigned by your doctor. Do not use in larger or less amounts or for longer than recommended. Fondaparinux is generally given each day before your bleeding condition improves. Follow the directions on your prescription label.
• Fondaparinux is injected under the skin. You may be shown how to use injections at house. Do not self-inject this medication if you do not fully understand how to give the injection and properly dispose of used needles and syringes.
• You must be sitting or lying down during the injection. Do not inject fondaparinux into a muscle or a vein.
• Prepare your doze in a syringe only when you are ready to give yourself an injection. Do not use the medicine if it has changed colors or has particles in it. Call your doctor for a new prescription.
• Use a various seat on your stomach every time you give the injection. Your care provider will show you the excellent places on your body to inject the medicine. Do not inject into the same seat two times in a row.
• Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Hold this container out of the reach of children and pets.
• Speak any doctor who treats you that you are using fondaparinux. If you need surgery or dental work, speak the surgeon or dentist onward of time that you are using this medication.
• To be certain this medicine is not causing deleterious effects, your blood and your stool (bowel movement) may need to be tested often. Your nerve and muscle function may also need to be tested. Visit your doctor regularly.
• Store at room temperature away from moisture and heat. Do not freeze.
• Use the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not use extra medication to create up the missed dose.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. Overdose can reason overweening bleeding.
• Avoid activities that may magnify your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Stop using fondaparinux and call your doctor at once if you have a serious side effect such as:
· unusual bleeding (nose, mouth, vagina, or rectum), bleeding from wounds or needle injections, any bleeding that will not stop;
· light bruising, purple or red pinpoint spots under your skin;
· pale skin, feeling light-headed or short of breath, rapid heart course, trouble concentrating;
· black or bloody stools, coughing up blood or vomit that looks like coffee grounds;
· numbness, tingling, or muscle weakness (especially in your legs and feet);
· loss of movement in any part of your body;
· sudden weakness, severe headache, confusion, or problems with speech, vision, or balance; or
· low potassium (confusion, uneven heart course, extreme thirst, heighten urination, leg discomfort, limp feeling).
• Smaller serious side effects may include:
· sleep problems (insomnia);
· mild skin rash;
· dizziness; or
· minor bleeding, rash, or itching where the medication was injected.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Much another drugs (including some over-the-counter medicines) can magnify your risk of bleeding, or your risk of developing blood clots near the brain or spinal cord during a spinal tap or epidural. It is very significant to speak your doctor about all medicines you have recently used, especially:
· dextran (Gentran, Hyskon);
· abciximab (ReoPro), eptifibatide (Integrilin), ticagrelor (Brilinta), tirofiban (Aggrastat);
· alteplase (Activase), reteplase (Retavase), tenecteplase (TNKase), urokinase (Abbokinase);
· anagrelide (Agrylin), cilostazol (Pletal), clopidogrel (Plavix), dipyridamole (Persantine, Aggrenox), eltrombopag (Promacta), oprelvekin (Neumega), prasugrel (Effient), romiplostim (Nplate), ticagrelor (Brilinta), ticlopidine (Ticlid);
· argatroban (Acova), bivalirudin (Angiomax), dabigatran (Pradaxa), lepirudin (Refludan);
· dalteparin (Fragmin), enoxaparin (Lovenox), rivaroxaban (Xarelto), heparin, tinzaparin (Innohep), warfarin (Coumadin, Jantoven);
· an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others; or
· salicylates such as aspirin, Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others.
• This list is not complete and another drugs may interact with fondaparinux. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.
• Your doctor or pharmacist can provide more information about fondaparinux.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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