VILAZODONE

(vil AZ oh done) Brand: Viibryd, Viibryd Starter

What is the most significant information I must know about vilazodone?

• You must not use vilazodone if you are being treated with methylene blue injection.

• Do not use vilazodone if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. After you stop taking vilazodone, you should wait at least 14 days till you start taking an MAOI.

• Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using vilazodone. Your family or another caregivers must also be alert to changes in your mood or symptoms.

• Do not give this medicine to anyone under 18 years old without medical advice.

What is vilazodone?

• Vilazodone is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs).

• Vilazodone is used to treat major depressive mess (MDD).

• Vilazodone may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking vilazodone?

• You must not use vilazodone if you are being treated with methylene blue injection.

• After you stop taking vilazodone, you should wait at least 14 days till you start taking an MAOI.

• To create certain vilazodone is safety for you, speak your doctor if you have:

· liver or kidney disease;

· a bleeding or blood clotting disorder;

· seizures or epilepsy;

· bipolar mess (manic depression); or

· a history of drug abuse or suicidal thoughts.

• FDA pregnancy category C. Taking an SSRI antidepressant during pregnancy may reason serious lung problems or another complications in the child. However, you may have a relapse of depression if you stop taking your antidepressant. Speak your doctor right away if you become pregnant while taking vilazodone. Do not start or stop taking this medication during pregnancy without your doctor's advice.

• It is not known whether vilazodone passes into breast milk or if it could harm a nursing child. Speak your doctor if you are breast-feeding a baby.

• Do not give this medicine to anyone under 18 years old without medical advice.

How must I take vilazodone?

• Follow all directions on your prescription label. Your doctor may occasionally change your doze to create certain you get the excellent results. Do not take this medication in larger or less amounts or for longer than recommended.

• Vilazodone works excellent if you take it with food.

• It may take different weeks or months till your symptoms improve. Hold using the medicine as directed and speak your doctor if your symptoms do not improve, or if they get worse.

• Do not stop using vilazodone suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using vilazodone.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. An overdose of vilazodone can be fatal.

What must I avoid while taking vilazodone?

• Ask your doctor till taking a nonsteroidal anti-inflammatory drug (NSAID) for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. Using an NSAID with vilazodone may reason you to bruise or bleed easily.

• Drinking alcohol can magnify some of the side effects of vilazodone.

• This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

What are the possible side effects of vilazodone?

• Get abnormal medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

• Call your doctor at once if you have:

· seizures (convulsions);

· light bruising, unusual bleeding (nose, mouth, vagina, or rectum), blood in your urine or stools, purple or red pinpoint spots under your skin;

· agitation, hallucinations, fever, quick heart course, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting;

· very stiff (rigid) muscles, tall fever, sweating, confusion, quick or uneven heartbeats, tremors, overactive reflexes, feeling like you might pass out;

· racing thoughts, unusual risk-taking behavior, decreased inhibitions, feelings of extreme happiness or sadness; or

· headache, slurred speech, severe weakness, muscle cramps, feeling unsteady, shallow breathing (breathing may stop).

• General side effects may include:

· diarrhea, mild nausea; or

· sleep problems (insomnia).

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect vilazodone?

• Taking vilazodone with another drugs that create you sleepy or slow your breathing can magnify these effects. Ask your doctor till taking vilazodone with a sleeping pill, narcotic pain medication, muscle relaxer, or medication for anxiety, depression, or seizures.

• Much drugs can interact with vilazodone. Not all possible interactions are listed here. Speak your doctor about all your medications and any you start or stop using during treatment with vilazodone, especially:

· any another antidepressant;

· bosentan;

· buspirone;

· imatinib;

· lithium;

· St. John's wort;

· tryptophan (sometimes called L-tryptophan)

· an antibiotic--clarithromycin, nafcillin, rifabutin, rifampin, rifapentine, telithromycin;

· antifungal medication--itraconazole, ketoconazole, posaconazole, voriconazole;

· heart medication--nicardipine, quinidine;

· hepatitis C medications--boceprevir, telaprevir;

· HIV/AIDS medication--atazanavir, delavirdine, efavirenz, fosamprenavir, indinavir, nelfinavir, nevirapine, ritonavir, saquinavir;

· migraine headache medicine--sumatriptan, zolmitriptan, and others;

· pain medication--fentanyl, tramadol; or

· seizure medication--carbamazepine, fosphenytoin, oxcarbazepine, phenobarbital, phenytoin, primidone.

• This list is not complete and much another drugs can interact with vilazodone. This includes prescription and over-the-counter medicines, vitamins, and herbal commodity. Give a list of all your medicines to any healthcare provider who treats you.

Where can I get more information?

• Your pharmacist can provide more information about vilazodone.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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