CLOPIDOGREL
(kloe PID oh grel) Brand: Plavix
What is the most significant information I must know about clopidogrel?
• Clopidogrel keeps your blood from coagulating (clotting) to prevent unwanted blood clots that can occur with determined heart or blood vessel conditions. Because of this drug action, clopidogrel can create it easier for you to bleed, even from a minor injury.
• Call your doctor or search abnormal medical attention if you have bleeding that will not stop. You may also have bleeding on the internal of your body, such as in your stomach or intestines. Call your doctor at once if you have black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds. These could be signs of bleeding in your digestive tract.
• Tell your doctor about all another medicines you use to prevent blood clots.
• If you need surgery or dental work, speak the surgeon or dentist onward of time that you take clopidogrel.
What is clopidogrel?
• Clopidogrel keeps the platelets in your blood from coagulating (clotting) to prevent unwanted blood clots that can occur with determined heart or blood vessel conditions.
• Clopidogrel is used to prevent blood clots after a last heart onslaught or stroke, and in people with determined disorders of the heart or blood vessels.
• Clopidogrel may also be used for another purposes not listed in this medicine guide.
What must I discuss with my healthcare provider till taking clopidogrel?
• Do not use this medication if you are allergic to clopidogrel, or if you have any active bleeding such as a stomach ulcer or bleeding in the brain (such as from a head injury).
• To create certain clopidogrel is safety for you, speak your doctor if you have:
· a bleeding or blood clotting mess, such as TTP (thrombocytopenic purpura) or hemophilia;
· a history of stroke, including TIA ("mini-stroke");
· a stomach ulcer or ulcerative colitis; or
· kidney disease.
• FDA pregnancy category B. This medicine is not expected to be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.
• It is not known whether clopidogrel passes into breast milk or if it could harm a nursing child. You must not breast-feed while using this medicine.
How must I take clopidogrel?
• Follow all directions on your prescription label. Do not take this medication in larger or less amounts or for longer than recommended.
• Take this medicine with a full glass of water.
• Clopidogrel can be taken with or without food.
• Because clopidogrel keeps your blood from clotting, it can also create it easier for you to bleed, even from a minor injury. Contact your doctor or search abnormal medical attention if you have bleeding that will not stop.
• If you need surgery or dental work, speak the surgeon or dentist onward of time that you are using clopidogrel. You may need to stop using the medication for at least 5 days till having surgery, to prevent overweening bleeding. Follow your doctor's instructions and start taking clopidogrel again as soon as possible.
• Do not stop using clopidogrel without first talking to your doctor. Use clopidogrel regularly to get the most benefit. Get your prescription refilled till you run out of medication completely.
• While using clopidogrel, you may need frequent blood trials at your doctor's office.
• Store at room temperature away from moisture and heat.
What happens if I miss a dose?
• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.
What happens if I overdose?
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
What must I avoid while taking clopidogrel?
• Avoid activities that may magnify your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
• Avoid drinking alcohol. It may magnify your risk of bleeding in your stomach or intestines.
What are the possible side effects of clopidogrel?
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Stop using clopidogrel and call your doctor at once if you have any of these serious side effects:
· nosebleed or another bleeding that will not stop;
· bloody or tarry stools, blood in your urine;
· coughing up blood or vomit that looks like coffee grounds;
· chest pain or hard feeling, pain spreading to the hand or shoulder, nausea, sweating, common ill feeling;
· sudden numbness or weakness, especially on one side of the body;
· sudden headache, confusion, problems with vision, speech, or balance;
· pale skin, weakness, fever, or jaundice (yellowing of the skin or eyes); or
· light bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin.
• General side effects may include itching.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
What another drugs will affect clopidogrel?
• Determined another medicines may magnify your risk of bleeding. Speak your doctor if you take aspirin, especially if you have had a stroke. Conversation to your doctor about whether you must take aspirin with clopidogrel. Ask a doctor or pharmacist till taking an NSAID (nonsteroidal anti-inflammatory drug), including ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
• Speak your doctor about all another medicines you use to prevent blood clots, such as:
· abciximab, eptifibatide, tirofiban;
· dalteparin, enoxaparin, tinzaparin;
· heparin, warfarin, Coumadin; or
· urokinase (Abbokinase).
• Speak your doctor about all another medicines you use, and those you start or stop using during your treatment with clopidogrel, especially:
· armodafinil or modafinil;
· fluoxetine or fluvoxamine;
· gemfibrozil;
· isoniazid;
· a cancer medication--dasatinib, letrozole, ibritumomab, or tositumomab;
· determined stomach acid reducers--cimetidine, esomeprazole, omeprazole;
· antifungal medication--fluconazole, ketoconazole, voriconazole;
· HIV medication--delavirdine, efavirenz, etravirine, tipranavir; or
· seizure medicine such as felbamate or oxcarbazepine.
• This list is not complete. Another drugs may interact with clopidogrel, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.
Where can I get more information?
• Your pharmacist can provide more information about clopidogrel.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.