(tye roe FYE ban) Brand: Aggrastat
• Do not receive this medicine if you are allergic to tirofiban, or to similar drugs such as abciximab (ReoPro) or eptifibatide (Integrilin).
• Do not receive this medicine if you have a stomach ulcer or ulcerative colitis, severe liver malady, severe tall blood pressure, a bleeding or blood clotting mess, a history of head injury, brain tumor, or blood clot in the brain (aneurysm), a stroke or any type of bleeding within the past 30 days, or any type of surgery, injury, or medical abnormal within the past 6 weeks.
• Tirofiban is not expected to be deleterious to an unborn child. However, aspirin is sometimes given with tirofiban, and aspirin can reason bleeding when it is taken during the recent 3 months of pregnancy. Aspirin can also reason side effects in a newborn baby.
• Tell your doctor if you are pregnant or plan to become pregnant during treatment with tirofiban and aspirin.
• Because tirofiban keeps your blood from coagulating (clotting) to prevent unwanted blood clots, it can also create it easier for you to bleed, even from a minor injury. Contact your doctor or search abnormal medical attention if you have bleeding that will not stop.
• Tirofiban keeps the platelets in your blood from coagulating (clotting) to prevent unwanted blood clots that can occur with determined heart or blood vessel conditions.
• Tirofiban is used to prevent blood clots or heart onslaught in people with severe chest pain or another conditions, and in those who are undergoing a procedure called angioplasty (to open blocked arteries).
• Tirofiban may also be used for purposes another than those listed in this medicine guide.
• Do not receive this medicine if you are allergic to tirofiban, or to similar drugs such as abciximab (ReoPro) or eptifibatide (Integrilin), or if you have:
· a stomach ulcer or ulcerative colitis;
· severe liver disease;
· a severe form of hypertension (high blood pressure);
· a bleeding or blood clotting mess, such as hemophilia or thrombocytopenia;
· a history of head injury, brain tumor, or blood clot in the brain (aneurysm);
· if you have had a stroke or any type of bleeding within the past 30 days; or
· if you have had any type of surgery, injury, or medical abnormal within the past 6 weeks.
• Till using tirofiban, speak your doctor if you are allergic to any drugs, or if you have:
· kidney malady (or if you are on dialysis);
· stomach ulcer;
· tall blood pressure;
· congestive heart failure; or
· a vision mess inclusion the blood vessels in your eyes.
• If you have any of these conditions, you may not be able to receive tirofiban, or you may need a dosage adjustment or particular trials during treatment.
• Tirofiban is not expected to be deleterious to an unborn child. However, aspirin is sometimes given with tirofiban, and aspirin can reason bleeding when it is taken during the recent 3 months of pregnancy. Aspirin can also reason side effects in a newborn baby.
• Tell your doctor if you are pregnant or plan to become pregnant during treatment with tirofiban and aspirin.
• It is not known whether tirofiban passes into breast milk or if it could harm a nursing child. Do not receive this medicine without telling your doctor if you are breast-feeding a baby.
• Tirofiban is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting.
• Tirofiban is generally given continuously for at least 2 days.
• Tirofiban is sometimes given together with aspirin.
• To be certain this medicine is not causing deleterious effects, your blood will need to be tested on a regular basis. Do not miss any scheduled visits to your doctor.
• Because tirofiban keeps your blood from coagulating (clotting) to prevent unwanted blood clots, it can also create it easier for you to bleed, even from a minor injury. Contact your doctor or search abnormal medical attention if you have bleeding that will not stop.
• Since tirofiban is generally given in a hospital or clinic setting as needed, it is not likely that you will miss a dose.
• Search abnormal medical attention if you think you have received too many of this medicine.
• Symptoms of a tirofiban overdose may include vomiting, feeling exhausted or short of breath, and severe bleeding.
• While you are receiving tirofiban, do not take aspirin or another NSAIDs (non-steroidal anti-inflammatory drugs) without your doctor's advice. NSAIDs include ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), mefenamic acid (Ponstel), meloxicam (Mobic), nabumetone (Relafen), piroxicam (Feldene), and others.
• Tirofiban lowers blood cells that help your blood clot. This can create it easier for you to bruise or bleed from an injury or minor cut. Avoid activities that magnify your risk of a bruising or bleeding injury. Use extra caution to avoid cuts when brushing your teeth or shaving.
• Avoid drinking alcohol while receiving tirofiban. Alcohol may magnify your risk of bleeding in your stomach or intestines.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have any of these serious side effects:
· nosebleed or another bleeding that will not stop;
· black, bloody, or tarry stools;
· coughing up blood or vomit that looks like coffee grounds;
· chest pain or hard feeling, pain spreading to the hand or shoulder, nausea, sweating, common ill feeling;
· sudden numbness or weakness, especially on one side of the body;
· sudden headache, confusion, problems with vision, speech, or balance;
· fever, chills, body aches, flu symptoms; or
· pale skin, light bruising or bleeding, weakness, fever, and urinating more or smaller than usual.
• Smaller serious side effects may also occur, such as:
· nausea, stomach pain;
· runny or stuffy nose, cough, sore throat; or
· mild headache or dizziness.
• Side effects another than those listed here may also occur. Conversation to your doctor about any side effect that seems unusual or that is especially bothersome. You may message side effects to FDA at 1-800-FDA-1088.
• Till receiving tirofiban, speak your doctor if you are using any of the next drugs:
· phenytoin (Dilantin);
· tamoxifen (Nolvadex);
· tolbutamide (Orinase);
· torsemide (Demadex);
· fluvastatin (Lescol);
· a blood thinner such as warfarin (Coumadin), heparin, ardeparin (Normiflo), dalteparin (Fragmin), danaparoid (Orgaran), enoxaparin (Lovenox), or tinzaparin (Innohep); or
· any another medications used to prevent blood clots, such as alteplase (Activase), anistreplase (Eminase), clopidogrel (Plavix), dipyridamole (Persantine), streptokinase (Kabikinase, Streptase), ticlopidine (Ticlid), or urokinase (Abbokinase).
• If you are using any of these drugs, you may not be able to receive tirofiban, or you may need dosage adjustments or particular trials during treatment.
• There may be another drugs not listed that can affect tirofiban. Speak your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start using a new medicine without telling your doctor.
• Your pharmacist has information about tirofiban written for health professionals that you may read.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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