CLOBAZAM

(KLOE ba zam) Brand: Onfi

What is the most significant information I must know about clobazam?

• You must not use clobazam if you are allergic to it.

• Till taking clobazam, speak your doctor if you have kidney or liver malady, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol.

• You may have thoughts about suicide while taking this medicine. Your doctor will need to check you at regular visits.

• Message any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself.

• This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

• Do not drink alcohol while taking clobazam.

• Clobazam may be habit-forming and should be used only by the face it was predesigned for. Hold the medicine in a secure seat where others can't get to it.

What is clobazam?

• Clobazam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Clobazam affects chemicals in the brain that may become unbalanced and reason anxiety.

• Clobazam is used in combination with another medications to treat seizures caused by Lennox-Gastaut syndrome, a severe form of childhood epilepsy that also causes developmental and behavior problems.

• Clobazam may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking clobazam?

• You must not take clobazam if you are allergic to it.

• To create certain you can safely take clobazam, speak your doctor if you have any of these another conditions:

· severe kidney disease;

· liver disease;

· a history of depression or suicidal thoughts or behavior; or

· a history of drug or alcohol addiction.

• You may have thoughts about suicide while taking this medicine. Speak your doctor if you have new or worsening depression or suicidal thoughts during the first different months of treatment, or whenever your doze is changed.

• Your family or another caregivers must also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

• Clobazam may be habit forming and must be used only by the face it was predesigned for. Never share clobazam with other face, especially somebody with a history of drug abuse or addiction. Hold the medicine in a seat where others can't get to it.

• FDA pregnancy category C. It is not known whether clobazam will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• Clobazam can create birth control pills smaller effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking clobazam.

• Clobazam can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

• The sedative effects of clobazam may recent longer in older adults. Accidental falls are general in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking clobazam.

• Clobazam must not be given to a baby younger than 2 years old.

How must I take clobazam?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your doze to create certain you get the excellent results.

• You may crush the clobazam tablet and mix the medication into a spoonful of applesauce to create swallowing easier. Swallow right away without chewing. Do not save the mixture for later use.

• Do not stop using clobazam without first talking to your doctor, even if you feel beautiful. You may have heighten seizures or unpleasant withdrawal symptoms if you stop using clobazam suddenly. You may need to use smaller and smaller till you stop the medicine completely.

• Use clobazam regularly to get the most benefit. Get your prescription refilled till you run out of medication completely. Contact your doctor if your seizures get worse or you have them more often while taking clobazam.

• Store at room temperature away from moisture and heat.

• Hold track of the amount of medication used from every new bottle. Clobazam is a drug of abuse and you must be aware if anyone is using your medication improperly or without a prescription.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. An overdose of clobazam can be fatal.

• Overdose symptoms may include severe drowsiness, confusion, extreme weakness, fainting, and weak or shallow breathing.

What must I avoid while taking clobazam?

• This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

• Do not drink alcohol while taking clobazam.

What are the possible side effects of clobazam?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Stop using clobazam and call your doctor at once if you have a serious side effect such as:

· confusion, hallucinations;

· fever, chills, cough with yellow or green mucus, feeling short of breath;

· feeling like you might pass out;

· pain or burning when you urinate;

· urinating smaller than normal or not at all; or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• Smaller serious side effects may include:

· drowsiness, dizziness;

· feeling weak, weary, or irritable;

· slurred speech, loss of balance or coordination;

· appetite changes;

· drooling;

· sleep problems (insomnia);

· constipation, vomiting, trouble swallowing;

· mild fever;

· dry cough.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect clobazam?

• Till using clobazam, speak your doctor if you regularly use another medicines that create you sleepy (such as cool or allergy medication, another sedatives, narcotic pain medication, sleeping pills, muscle relaxers, and medication for seizures, depression, or anxiety). They can add to sleepiness caused by clobazam.

• Speak your doctor about all another medicines you use, especially:

· cimetidine (Tagamet);

· fluvastatin (Lescol);

· indomethacin (Indocin);

· probenecid (Benemid);

· ropinirole (Requip);

· tamsulosin (Flomax);

· terbinafine (Lamisil);

· ticlopidine (Ticlid);

· tolterodine (Detrol);

· felbamate (Felbatol) or oxcarbazepine (Trileptal);

· lansoprazole (Prevacid) or omeprazole (Prilosec);

· ADHD medicine such as atomoxetine (Strattera), dextroamphetamine (Adderall), methylphenidate (Ritalin, Daytrana, Metadate, Concerta);

· any type of antidepressant;

· antifungal medicine such as fluconazole (Diflucan), ketoconazole (Nizoral), or voriconazole (Vfend);

· anti-malaria medicine such as chloroquine (Aralen), pyrimethamine (Daraprim), or quinine (Qualaquin);

· cancer medication such as doxorubicin (Adriamycin, Doxil), gefitinib (Iressa), letrozole (Femara), lomustine (CeeNU), or tamoxifen (Soltamox);

· cough medication such as dextromethorphan (Robitussin Maximum Power, Vicks 44, and others) or dihydrocodeine (Alahist DHC, J-Max DHC, Pancof-PD, Panlor, Trezix, Welltuss EXP, and others);

· heart or blood pressure medicine such as amiodarone (Cordarone, Pacerone), captopril (Capoten), flecainide (Tambocor), metoprolol (Lopressor, Toprol), nicardipine (Cardene), procainamide (Procan, Pronestyl), propafenone (Rythmol), propranolol (Inderal), quinidine (Quin-G), and others;

· HIV/AIDS medicine such as delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), etravirine (Intelence), or ritonavir (Norvir, Kaletra);

· medication to treat psychiatric disorders, such as aripiprazole (Abilify), clozapine (Clozaril, FazaClo), haloperidol (Haldol), risperidone (Risperdal), and others; or

· pain medication such as codeine (Tylenol #3), hydrocodone (Lortab, Vicodin), oxycodone (OxyContin, Percocet), tramadol (Ultram, Ultracet), and others.

• This list is not complete and another drugs may interact with clobazam. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about clobazam.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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