PROPRANOLOL

(pro PRAN oh lol) Brand: Inderal, Inderal LA, InnoPran XL

What is the most significant information I must know about propranolol?

• You must not use this medicine if you are allergic to propranolol, if you have asthma, a slow heart course, or a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker).

• If you need surgery, speak the surgeon onward of time that you are using propranolol. You may need to stop using the medication for a short time.

• Do not skip doses or stop using propranolol without first talking to your doctor. You may need to use smaller and smaller till you stop the medicine completely.

• Avoid drinking alcohol. It may magnify your blood levels of propranolol.

• Propranolol is only part of a complete program of treatment for hypertension that may also include diet, exercice, and weight control. Follow your diet, medicine, and exercice routines very closely if you are being treated for hypertension.

• If you are being treated for tall blood pressure, hold using this medicine even if you feel well. Tall blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

What is propranolol?

• Propranolol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

• Propranolol is used to treat tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders, and another heart or circulatory conditions. It is also used to treat or prevent heart onslaught, and to reduce the severity and frequency of migraine headaches.

• Propranolol may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking propranolol?

• To create certain you can safely take propranolol, speak your doctor if you have any of these another conditions:

· a muscle disorder;

· bronchitis, emphysema, or another breathing disorders;

· diabetes (propranolol can create it harder for you to speak when you have low blood sugar);

· low blood pressure;

· congestive heart failure;

· depression;

· liver or kidney disease;

· a thyroid disorder;

· pheochromocytoma; or

· problems with circulation (such as Raynaud's syndrome).

• FDA pregnancy category C. It is not known whether propranolol will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• Propranolol can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take propranolol?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• You may take propranolol with or without food, but take it the same way every time.

• Take the medication at the same time every day.

• Do not crush, chew, interrupt, or open an extended-release capsule. Swallow it intact. Breaking or opening the pill may reason too many of the drug to be released at one time.

• To be certain you get the correct doze, measure the liquid with a marked measuring spoon or medication cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

• Do not skip doses or stop using propranolol without first talking to your doctor. You may need to use smaller and smaller till you stop the medicine completely.

• Your blood pressure will need to be checked often. Visit your doctor regularly.

• If you need surgery, speak the surgeon onward of time that you are using propranolol. You may need to stop using the medication for a short time.

• This medicine can reason unusual results with determined medical trials. Speak any doctor who treats you that you are using propranolol.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• For regular (short-acting) propranolol: Take the missed doze as soon as you remember. Skip the missed doze if your following doze is smaller than 4 hours away.

• For extended-release propranolol (Inderal LA, InnoPran XL and others): Take the missed doze as soon as you remember. Skip the missed doze if your following doze is smaller than 8 hours away.

• Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include slow or uneven heartbeats, dizziness, weakness, or fainting.

What must I avoid while taking propranolol?

• Avoid drinking alcohol. It may magnify your blood levels of propranolol.

• Avoid getting up too quick from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

What are the possible side effects of propranolol?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have a serious side effect such as:

· quick, slow, or uneven heartbeats;

· feeling light-headed, fainting;

· feeling short of breath, even with mild exertion;

· swelling of your ankles or feet;

· nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

· cool feeling in your hands and feet;

· depression, confusion, hallucinations; or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• Smaller serious side effects may include:

· nausea, vomiting, diarrhea, constipation, stomach cramps;

· decreased sex drive, impotence, or difficulty having an orgasm;

· sleep problems (insomnia); or

· weary feeling.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect propranolol?

• Speak your doctor about all another medications you use, especially:

· cimetidine (Tagamet);

· clonidine (Catapres);

· digitalis (digoxin, Lanoxin);

· dobutamine (Dobutrex);

· haloperidol (Haldol);

· isoproterenol (Isuprel);

· a blood thinner such as warfarin (Coumadin, Jantoven);

· an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Janimine, Tofranil), and others;

· an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate);

· aspirin or another NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others;

· doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin);

· heart or blood pressure medication such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide), diltiazem (Cartia, Cardizem), nifedipine (Nifedical, Procardia), reserpine (Serpasil), verapamil (Calan, Covera, Isoptin, Verelan), and others;

· amiodarone (Cordarone, Pacerone), propafenone (Rythmol), quinidine (Quin-G); or

· an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

• This list is not complete and another drugs may interact with propranolol. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about propranolol.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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