ERGOTAMINE

(er GOT a meen) Brand: Ergomar

What is the most significant information I must know about ergotamine?

• This medicine can harm an unborn child or a nursing child. Do not take ergotamine if you are pregnant or breast-feeding.

• Do not take this medicine if you are allergic to ergotamine or another ergot medicines, or if you have a history of heart malady, angina (chest pain), blood circulation problems, history of a heart onslaught or stroke, coronary artery malady, uncontrolled tall blood pressure, severe liver or kidney malady, or a serious infection.

• Using determined medications together with ergotamine can reason even greater decreases in blood flow than ergotamine used alone, which can lead to dangerous side effects. Tell your doctor about all another medications you are using.

• Also speak your doctor about all of your medical conditions, especially tall blood pressure, liver or kidney malady, or risk factors for coronary artery malady (diabetes, tall blood pressure or cholesterol, menopause or hysterectomy, smoking, taking birth control pills, being overweight, having a family history of coronary artery malady, or being a man older than 40).

• This medicine will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

• Never take more than your predesigned doze of ergotamine. An overdose can be fatal.

What is ergotamine?

• Ergotamine is in a group of drugs called ergot alkaloids (ER-got AL-ka-loids). It works by narrowing the blood vessels near the brain. Ergotamine also affects blood flow patterns that are associated with determined types of headaches.

• Ergotamine is used to treat a migraine type headache.

• This medicine will only treat a headache that has already begun. It will not prevent migraine headaches or reduce the number of attacks.

• Ergotamine must not be used to treat general tension headaches or any headache that seems to be various from your normal migraine headaches.

• Ergotamine may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking ergotamine?

• Do not take this medicine if you are allergic to ergotamine or similar medications such as Cafergot, D.H.E. 45, Migergot, Migranal, or Methergine.

• Do not take ergotamine if you are pregnant or breast-feeding, or if you have:

· a history of heart malady, angina (chest pain), blood circulation problems, or history of a heart onslaught or stroke;

· coronary artery malady or "hardening of the arteries";

· uncontrolled tall blood pressure;

· severe liver disease;

· severe kidney malady; or

· a serious infection called sepsis.

• Using determined medications together with ergotamine can reason even greater decreases in blood flow than ergotamine used alone, which can lead to dangerous side effects. Do not take ergotamine if you are also using any of the next medications:

· conivaptan (Vaprisol), imatinib (Gleevec), isoniazid (for treating tuberculosis), or nefazodone (an antidepressant);

· diclofenac (Arthrotec, Cataflam, Voltaren, Flector Patch, Solareze);

· clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or telithromycin (Ketek);

· clotrimazole (Mycelex Troche), itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), or voriconazole (Vfend);

· heart or blood pressure medicine such as diltiazem (Cardizem, Dilacor, Tiazac), nicardipine (Cardene), quinidine (Quin-G), or verapamil (Calan, Covera, Isoptin, Verelan); or

· HIV/AIDS medication such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase, Fortovase), or ritonavir (Norvir).

• Ergotamine can reason rare but serious side effects on the heart, including heart onslaught or stroke. To create certain you can safely take ergotamine, speak your doctor if you have any of these another conditions:

· tall blood pressure;

· liver disease;

· kidney malady; or

· coronary artery malady (or risk factors that include diabetes, menopause, smoking, being overweight, having tall blood pressure or tall cholesterol, having a family history of coronary artery malady, being older than 40 and a man, or being a woman who has had a hysterectomy).

• FDA pregnancy category X. Ergotamine can reason birth defects. Do not use if you are pregnant. Speak your doctor right away if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.

• Ergotamine can pass into breast milk and may harm a nursing child. Ergotamine may also decrease milk manufacture. Do not use if you are breast-feeding a baby.

How must I take ergotamine?

• Take exactly as predesigned by your doctor. Never take more than your predesigned doze of ergotamine. Follow the directions on your prescription label. Speak your doctor if the medication seems to stop working as well in treating your migraine attacks. Ergotamine is not for daily use.

• Take the first doze of ergotamine as soon as you announcement headache symptoms, or after an onslaught has already begun. Seat 1 ergotamine tablet under your tongue.

• If your headache does not completely go away, you may take a second tablet after at least 30 minutes have passed, and a third tablet if needed after other 30 minutes have passed (a total of 3 tablets).

• If you still have migraine symptoms after taking a total of 3 tablets, call your doctor. Do not take more than a total of 3 tablets in any 24-hour period. Do not take more than a total of 5 tablets over a period of 7 days.

• Do not give this medicine to anyone else, even if they have the same headache symptoms you have. Ergotamine can be dangerous if it is used to treat headache in a face who has not been diagnosed by a doctor as having true migraine headaches.

• Store at room temperature away from moisture, heat, and easy. Do not take any stored ergotamine if the expiration date on the label has passed.

What happens if I miss a dose?

• Since ergotamine is taken only when needed, you are not likely to miss a dose.

• Do not take more than 3 ergotamine tablets for day or more than 5 tablets for week.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. An overdose of ergotamine can be fatal.

• Overdose can reason vomiting, confusion, drowsiness, weak pulses in your arms and legs, numbness and tingling or pain in your hands or foots, blue-colored fingers or toes, fainting, and seizure (convulsions).

What must I avoid while taking ergotamine?

• Do not take ergotamine within 24 hours till or after using other migraine headache medication, including:

· dihydroergotamine (D.H.E. 45, Migranal), caffeine and ergotamine (Cafergot, Ercaf, Wigraine), ergonovine (Ergotrate), methylergonovine (Methergine), methysergide (Sansert); or

· almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), sumatriptan (Imitrex), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig).

• Grapefruit and grapefruit juice may interact with ergotamine and lead to potentially dangerous effects. Discuss the use of grapefruit commodity with your doctor. Do not magnify or decrease the amount of grapefruit commodity in your diet without first talking to your doctor.

What are the possible side effects of ergotamine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop taking ergotamine and call your doctor at once if you have a serious side effect such as:

· sudden numbness or weakness, especially on one side of the body;

· sudden headache, confusion, problems with vision, speech, or balance;

· quick or slow heart rate;

· muscle pain in your arms or legs;

· leg weakness;

· numbness or tingling and a pale or blue-colored appearance in your fingers or toes;

· severe pain in your stomach or lower back;

· urinating smaller than normal or not at all;

· swelling or itching in any part of your body;

· cough with stabbing chest pain and trouble breathing; or

· dangerously tall blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

• Smaller serious side effects may include:

· dizziness, spinning sensation;

· weakness;

· nausea, vomiting; or

· mild itching.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect ergotamine?

• Much drugs can interact with ergotamine. Adown is just a partial list. Conversation with your doctor till taking ergotamine if you are also taking:

· birth control pills;

· zileuton (Zyflo);

· cool or allergy medications;

· nicotine (Nicoderm, Nicorette);

· diet pills, stimulants, or medicine to treat ADHD (such as Ritalin or Adderall);

· an antidepressant such as fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), nefazodone (Serzone), paroxetine (Paxil), sertraline (Zoloft), and others;

· an antibiotic such as metronidazole (Flagyl);

· clotrimazole (Mycelex Troche), fluconazole (Diflucan), or another antifungal medication;

· nitroglycerin or another nitrate medicines such as isosorbide (Isordil, Dilatrate, Imdur, Monoket); or

· heart or blood pressure medicine such as atenolol (Tenormin), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others.

• This list is not complete and another drugs may interact with ergotamine. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about ergotamine.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.