NITROGLYCERIN (ORAL/SUBLINGUAL)

(NYE troe GLI ser in (OR al/sub LIN gwal)) Brand: Nitro-Time, Nitrolingual, Nitrolingual Duo Pack, Nitromist, Nitrostat

What is the most significant information I must know about nitroglycerin?

• Do not use nitroglycerin if you are taking sildenafil (Viagra, Revatio), tadalafil (Cialis), or vardenafil (Levitra). Serious, life-threatening side effects can occur if you take nitroglycerin while you are using sildenafil.

• Nitroglycerin can reason severe headaches, especially when you first start using it. These headaches may gradually become smaller severe as you continue to use nitroglycerin. Do not stop taking the medicine. Ask your doctor till using any headache pain medication.

What is nitroglycerin?

• Nitroglycerin is in a group of drugs called nitrates. Nitroglycerin dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.

• Nitroglycerin is used to treat or prevent attacks of chest pain (angina).

• Nitroglycerin may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking nitroglycerin?

• Do not use this medicine without the advice of a doctor if you have early signs of a heart onslaught (chest pain or hard feeling, pain spreading to the hand or shoulder, nausea, sweating, common ill feeling). Seek abnormal medical attention if you have symptoms of a heart attack.

• You must not use this medicine if you are allergic to nitroglycerin or another nitrates such as isosorbide dinitrate (Dilatrate, Isordil, Isochron) or isosorbide mononitrate (Imdur, ISMO, Monoket), or if you have:

· severe anemia (a lack of red blood cells); or

· a brain injury, hemorrhage, or tumor.

• To create certain you can safely take nitroglycerin, speak your doctor if you have any of these another conditions:

· congestive heart failure;

· a history of heart onslaught, stroke, or head injury;

· low blood pressure;

· glaucoma;

· migraine headaches; or

· liver disease.

• FDA pregnancy category C. It is not known whether nitroglycerin will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• It is not known whether nitroglycerin passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take nitroglycerin?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• If possible, try to rest or remain seated when you use this medicine. Nitroglycerin can reason dizziness or fainting.

• If you use nitroglycerin sublingual spray to treat an angina onslaught: At the first sign of an onslaught, apply the spray directly on or under your tongue. Close your mouth after every spray. Do not inhale the spray. Do not shake the spray till or during use. You may use additional sprays each 5 minutes, but not more than 3 sprays in 15 minutes.

• You may use nitroglycerin spray within 5 to 10 minutes till an activity you think might reason chest pain. Follow your doctor's instructions.

• The nitroglycerin sublingual tablet must be placed under your tongue and allowed to dissolve slowly. Do not chew or swallow it. You may use additional tablets each 5 minutes, but not more than 3 tablets in 15 minutes.

• Search abnormal medical attention if your chest pain gets worse or lasts more than 5 minutes, especially if you have trouble breathing or feel weak, dizzy, or nauseated, or lightheaded.

• You may feel a slight burning or stinging in your mouth when you use this medicine. However, this sensation is not a sign of how well the medicine is working. Do not use more medicine just because you do not feel a burning or stinging.

• Do not crush, chew, interrupt, or open an extended-release capsule. Swallow the pill intact. It is specially made to release medication slowly in the body. Breaking or opening the pill would reason too many of the drug to be released at one time.

• This medicine can reason unusual results with determined medical trials. Speak any doctor who treats you that you are using nitroglycerin.

• Hold this medication on arm at all times in case of an angina onslaught. Get your prescription refilled till you run out of medication completely.

• If you take nitroglycerin on a regular schedule to prevent angina, do not stop taking it suddenly or you could have a severe onslaught of angina.

• Store the tablets in the glass container at room temperature, away from moisture and heat. Hold the spray away from open flame or tall heat, such as in a machine on a hot day. The canister may explode if it gets too hot.

What happens if I miss a dose?

• Since nitroglycerin is taken as needed, you may not be on a dosing schedule. If you are taking the medicine regularly, take the missed doze as soon as you remember. Skip the missed doze if your following doze is smaller than 2 hours away. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. An overdose of nitroglycerin can be fatal.

• Overdose symptoms may include a severe throbbing headache, confusion, fever, quick or pounding heartbeats, dizziness, vision problems, nausea, vomiting, bloody diarrhea, trouble breathing, cool or clammy skin, feeling light-headed, fainting, and seizures.

What must I avoid while taking nitroglycerin?

• Nitroglycerin can reason side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

• Avoid drinking alcohol. It can magnify some of the side effects of nitroglycerin, such as dizziness, drowsiness, feeling light-headed, or fainting.

What are the possible side effects of nitroglycerin?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have a serious side effect such as:

· quick, slow, pounding, or uneven heart rate;

· blurred vision or dry mouth;

· nausea, vomiting, sweating, pale skin, feeling like you might pass out; or

· fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.

• Smaller serious side effects may include:

· mild burning or tingling with the tablet in your mouth;

· warmth, redness, or tingly feeling under your skin; or

· feeling weak or dizzy.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect nitroglycerin?

• Much drugs can interact with nitroglycerin. Adown is just a partial list. Speak your doctor if you are using:

· alteplase (Activase);

· aspirin or heparin;

· bladder or urinary medications such as oxybutynin (Ditropan) or tolterodine (Detrol);

· blood pressure medication;

· bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva);

· dihydroergotamine (D.H.E. 45, Migranal) or ergotamine (Ergomar, Cafergot, and others);

· an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), clomipramine (Anafranil), imipramine (Tofranil), and others;

· a beta-blocker such as atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), and others;

· a calcium channel blocker such as diltiazem (Tiazac, Cardizem), nifedipine (Procardia), nimodipine (Nimotop), verapamil (Calan, Covera, Verelan), and others;

· irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, and others), or propantheline (Pro-Banthine);

· any medicine that causes dry mouth; or

· medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), thioridazine (Mellaril), and others.

• This list is not complete and there are much another drugs that can interact with nitroglycerin. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about nitroglycerin.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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