CARVEDILOL

(KAR ve dil ole) Brand: Coreg, Coreg CR

What is the most significant information I must know about carvedilol?

• You must not take this medicine if you are allergic to carvedilol, or if you have asthma, bronchitis, emphysema, severe liver malady, or a serious heart condition such as heart block, sick sinus syndrome, or slow heart course (unless you have a pacemaker).

• If you need surgery, speak the surgeon onward of time that you are using carvedilol. You may need to stop using the medication for a short time.

• Do not stop taking carvedilol without first talking to your doctor. Stopping suddenly may create your condition worse.

• If you are being treated for tall blood pressure, hold using this medicine even if you feel well. Tall blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

What is carvedilol?

• Carvedilol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

• Carvedilol is used to treat heart failure and hypertension (high blood pressure). It is also used after a heart onslaught that has caused your heart not to exhaust as well.

• Carvedilol may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking carvedilol?

• You must not take this medicine if you are allergic to carvedilol, or if you have:

· asthma, bronchitis, emphysema;

· severe liver malady; or

· a serious heart condition such as heart block, sick sinus syndrome, or slow heart course (unless you have a pacemaker).

• To create certain you can safely take carvedilol, speak your doctor if you have any of these another conditions:

· diabetes (taking carvedilol can create it harder for you to speak when you have low blood sugar);

· angina (chest pain);

· low blood pressure;

· kidney disease;

· liver disease;

· a thyroid disorder;

· pheochromocytoma (tumor of the adrenal gland);

· circulation problems (such as Raynaud's syndrome); or

· a history of allergies.

• FDA pregnancy category C. It is not known whether carvedilol will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• It is not known whether carvedilol passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are taking carvedilol.

How must I take carvedilol?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your doze to create certain you get the excellent results.

• Carvedilol works excellent if you take it with food.

• Take carvedilol at the same time each day. Do not skip doses or stop taking carvedilol without first talking to your doctor. Stopping suddenly may create your condition worse.

• You may open the carvedilol capsule and sprinkle the medication into a spoonful of pudding or applesauce to create swallowing easier. Swallow right away without chewing. Do not save the mixture for later use. Discard the empty capsule.

• If you are switched from carvedilol tablets to carvedilol extended-release capsules (Coreg CR), your daily total doze of this medication may be higher or lower than till. Older adults may be more likely to become dizzy or feel faint when switching from tablets to extended-release capsules. Follow your doctor's instructions.

• Your blood pressure will need to be checked often. Visit your doctor regularly.

• If you need surgery, speak the surgeon onward of time that you are using carvedilol. You may need to stop using the medication for a short time.

• Carvedilol can affect your pupils during cataract surgery. Speak your eye surgeon onward of time that you are using this medicine. Do not stop using carvedilol till surgery unless your surgeon tells you to.

• Carvedilol is only part of a complete program of treatment for hypertension that may also include diet, exercice, and weight control. Follow your diet, medicine, and exercice routines very closely if you are being treated for hypertension.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, and seizure (convulsions).

What must I avoid while taking carvedilol?

• Carvedilol may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

• Avoid drinking alcohol within 2 hours till or after taking extended-release carvedilol (Coreg CR). Also avoid taking medicines or another commodity that might contain alcohol. Alcohol may reason the carvedilol in Coreg CR to be released too quickly into the body. Check the labels of any prescription or over-the-counter medicines you take to see if they contain alcohol (also called ethanol).

• Avoid getting up too quick from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

What are the possible side effects of carvedilol?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have a serious side effect such as:

· feeling like you might pass out;

· slow or uneven heartbeats;

· chest pain, dry cough, wheezing, chest tightness, trouble breathing;

· feeling short of breath, even with mild exertion;

· swelling, rapid weight gain;

· numbness or cool feeling in your hands and foots;

· loss of bladder control;

· pale skin, feeling light-headed, rapid heart course, trouble concentrating;

· tall blood sugar (increased thirst, heighten urination, famine, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss); or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• Smaller serious side effects may include:

· dizziness, drowsiness;

· nausea, vomiting, diarrhea;

· dry eyes;

· feeling weak or tired;

· joint pain;

· cough; or

· decreased sex drive, impotence, or difficulty having an orgasm.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect carvedilol?

• Much drugs can interact with carvedilol. Adown is just a partial list. Speak your doctor if you are using:

· allergy treatments (or if you are undergoing allergy skin-testing);

· cimetidine (Tagamet);

· cyclosporine (Gengraf, Neoral, Sandimmune);

· fluconazole (Diflucan);

· insulin or oral diabetes medication;

· rifampin (Rifadin, Rifater, Rifamate);

· an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), bupropion (Wellbutrin, Zyban), clomipramine (Anafranil), desipramine (Norpramin), duloxetine (Cymbalta), fluoxetine (Prozac, Sarafem), imipramine (Tofranil), paroxetine (Paxil), or sertraline (Zoloft);

· heart or blood pressure medication such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta), clonidine (Catapres), diltiazem (Cartia, Cardizem), nifedipine (Nifedical, Procardia), reserpine, verapamil (Calan, Covera, Isoptin, Verelan), and others;

· a heart rhythm medicine such as amiodarone (Cordarone, Pacerone), digoxin (digitalis, Lanoxin), flecainide (Tambocor), propafenone (Rythmol), or quinidine (Quin-G);

· HIV or AIDS medication such as delavirdine (Rescriptor) or ritonavir (Norvir, Kaletra);

· an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate);

· medication to prevent or treat nausea and vomiting, such as metoclopramide (Reglan) or promethazine (Pentazine, Phenergan, Anergan, Antinaus);

· medication to treat psychiatric disorders, such as aripiprazole (Abilify), chlorpromazine (Thorazine), fluphenazine (Permitil, Prolixin), haloperidol (Haldol), perphenazine (Trilafon), or thioridazine (Mellaril); or

· a narcotic such as methadone (Methadose, Diskets, Dolophine) or propoxyphene (Daron, Darvocet).

• This list is not complete and there are much another drugs that can interact with carvedilol. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor. Hold a list of all your medicines and show it to any healthcare provider who treats you.

Where can I get more information?

• Your pharmacist can provide more information about carvedilol.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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