Cisapride (Propulsid); Prokinetic agent; Susp: 1 mg/mL
Tab, scored: 10, 20 mg; 0.15-0.3 mg/kg/dose PO tid-qid (max 10 mg/dose).
Only available via limited-access protocol: Contact Janssen Pharmaceuticals at 1-800-Janssen. 12-lead EKG measuring QTc intervals must be
done for all patients before initiating therapy.
Absolutely contraindicated with
ketoconazole,
fluconazole,
erythromycin, and
clarithromycin due to rare,
fatal arrhythmias.