(ten EK te plase) Brand: TNKase
• You must not receive this medicine if you have inside bleeding, brain cancer or aneurysm, a history of stroke, a bleeding or blood clotting mess, or if you have had brain or spinal cord injury or surgery within the past 2 months.
• Till you are treated with tenecteplase, speak your doctor if you have a blood vessel mess of the eye, severe liver or kidney malady, tall blood pressure, an infection of the lining of your heart (also called bacterial endocarditis), a last history of stomach or urinary bleeding, if you have recently had a child, or if you have recently had a serious injury or major surgery.
• Also speak your doctor if you take a blood thinner such as warfarin (Coumadin), or another medications to treat or prevent blood clots.
• Speak your caregivers at once if you have a serious side effect such as blood in your urine or stools, nosebleed, coughing up blood, bleeding from a skin wound or the IV needle, quick or slow heart course, or feeling like you might pass out.
• Tenecteplase may reason rare but serious side effects such as: purple discoloration of your legs or toes, sudden numbness or weakness, problems with vision or speech, chest pain or hard feeling, urinating smaller than normal or not at all, muscle pain or tenderness, dark colored urine, unusual sensations in your back, numbness or tingling in your legs or foots, muscle weakness or loss of use, or loss of bowel or bladder control.
• Tenecteplase can reason you to have unusual results with blood trials. Speak any doctor who treats you that you have recently received tenecteplase.
• Tenecteplase is in a group of drugs called tissue plasminogen activators (TPAs). It works by causing the body to over-produce a stuff called plasmin to dissolve unwanted blood clots.
• Tenecteplase is used to prevent death from a heart onslaught (acute myocardial infarction).
• Tenecteplase may also be used for another purposes not listed in this medicine guide.
• You must not receive this medicine if you have:
· inside bleeding;
· a history of stroke;
· brain cancer;
· brain aneurysm;
· a bleeding or blood clotting mess (such as hemophilia); or
· if you have had brain or spinal cord injury or surgery within the past 2 months.
• If you have determined conditions, you may need a doze adjustment or particular trials to safely receive this medicine. Till you receive tenecteplase, speak your doctor if you have:
· a blood vessel mess of the eye;
· severe liver or kidney disease;
· tall blood pressure;
· an infection of the lining of your heart (also called bacterial endocarditis);
· a last history of bleeding in your stomach, intestines, or urinary tract;
· if you have recently had a child; or
· if you have recently had a serious injury or major surgery.
• FDA pregnancy category C. Tenecteplase may be deleterious to an unborn child. Till you receive this medicine, speak your doctor if you are pregnant.
• It is not known whether tenecteplase passes into breast milk or if it could harm a nursing child. Till you receive this medicine , speak your doctor if you are breast-feeding a baby.
• Tenecteplase is given as an injection through a needle placed into a vein. You will receive this injection in a hospital or abnormal setting. It is generally given as soon as possible after the first signs of heart onslaught occur.
• Tenecteplase can reason you to have unusual results with blood trials. Speak any doctor who treats you that you have recently received tenecteplase.
• Tenecteplase is generally given as a single doze, so you are not likely to be on a dosing schedule.
• Since tenecteplase is given by a healthcare professional, you are not likely to receive an overdose. Symptoms of a tenecteplase overdose are not known.
• Follow your doctor's instructions about any restrictions on food, beverages, or activity after you receive tenecteplase.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Speak your caregivers at once if you have a serious side effect such as:
· blood in your urine or stools;
· nosebleed, coughing up blood;
· bleeding from a last injury or surgery incision;
· bleeding near the IV needle;
· quick, slow, or uneven heart course; or
· feeling like you might pass out.
• Rare but serious side effects may include:
· purple discoloration of your legs or toes;
· severe pain in your upper stomach spreading to your back, nausea and vomiting, quick heart rate;
· sudden numbness, weakness, headache, confusion, or problems with vision, speech, or balance;
· chest pain or hard feeling, pain spreading to the hand or shoulder, nausea, sweating, common ill feeling;
· swelling, weight gain, feeling short of breath, urinating smaller than normal or not at all;
· drowsiness, confusion, mood changes, heighten thirst, loss of appetite, nausea and vomiting;
· muscle pain or tenderness with fever or flu symptoms and dark colored urine;
· pain or unusual sensations in your back;
· numbness, weakness, or tingly feeling in your legs or feet;
· muscle weakness or loss of use; or
· loss of bowel or bladder control.
• Smaller serious side effects may include mild nausea or dizziness.
• This is not a complete list of side effects and others may occur. Speak your doctor about any unusual or bothersome side effect. You may message side effects to FDA at 1-800-FDA-1088.
• Speak your doctor about all another medications you have recently used or received, especially:
· a blood thinner such as warfarin (Coumadin);
· abciximab (ReoPro);
· alteplase (Activase);
· anistreplase (Eminase);
· dipyridamole (Persantine);
· eptifibatide (Integrilin);
· heparin;
· streptokinase (Kabikinase, Streptase);
· tirofiban (Aggrastat); or
· urokinase (Abbokinase).
• This list is not complete and there may be another drugs that can interact with tenecteplase. Speak your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start a new medicine without telling your doctor.
• Your doctor or pharmacist can provide more information about tenecteplase.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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