PRASUGREL

(PRA soo grel) Brand: Effient

What is the most significant information I must know about prasugrel?

• Prasugrel keeps your blood from coagulating (clotting) to prevent unwanted blood clots that can occur with determined heart or blood vessel conditions. Because of this drug action, prasugrel can create it easier for you to bleed, even from a minor injury. Contact your doctor or search abnormal medical attention if you have bleeding that will not stop.

• You may also have bleeding on the internal of your body, such as in your stomach or intestines. Call your doctor at once if you have black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds. These could be signs of bleeding in your digestive tract.

• If you need to have any type of surgery or dental work, speak the surgeon or dentist onward of time that you are using prasugrel. You may need to stop using the medication for at least 7 days till surgery to prevent overweening bleeding.

• While you are taking prasugrel, do not take NSAIDs (non-steroidal anti-inflammatory drugs) without your doctor's advice. NSAIDs include ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), mefenamic acid (Ponstel), meloxicam (Mobic), nabumetone (Relafen), piroxicam (Feldene), and others.

What is prasugrel?

• Prasugrel keeps the platelets in your blood from coagulating (clotting) to prevent unwanted blood clots that can occur with determined heart or blood vessel conditions.

• Prasugrel is used to prevent blood clots in people with acute coronary syndrome who are undergoing a procedure after a last heart onslaught or stroke, and in people with determined disorders of the heart or blood vessels.

• Prasugrel may also be used for another purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking prasugrel?

• Do not use this medicine if you are allergic to prasugrel, or if you have any active bleeding such as a stomach ulcer or bleeding in the brain (such as from a head injury), or a history of stroke, including TIA ("mini-stroke").

• If you have any of these another conditions, you may need a doze adjustment or particular trials to safely take this medication:

· a bleeding or blood clotting mess, such as hemophilia;

· a stomach ulcer;

· severe liver malady; or

· just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

• FDA pregnancy category B. This medicine is not expected to be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether prasugrel passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take prasugrel?

• Take this medicine exactly as it was predesigned for you. Do not take the medicine in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

• Take this medicine with a full glass of water.

• Prasugrel can be taken with or without food.

• Do not crush or interrupt a prasugrel tablet. Swallow the pill whole.

• Because prasugrel keeps your blood from coagulating (clotting) to prevent unwanted blood clots, it can also create it easier for you to bleed, even from a minor injury. Contact your doctor or search abnormal medical attention if you have bleeding that will not stop.

• You may also have bleeding on the internal of your body, such as in your stomach or intestines. Call your doctor at once if you feel very weak or dizzy, or if you have black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds. These could be signs of bleeding in your digestive tract.

• Do not stop taking this medicine without first talking to your doctor. Stopping suddenly may create your condition worse.

• Store prasugrel at room temperature away from moisture and heat. Hold the tablets in their original container, along with the packet of moisture-absorbing preservative that comes with prasugrel tablets.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. If it is nearly time for your following doze, skip the missed doze and take the medication at your following regularly scheduled time. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medicine.

• Overdose symptoms may include vomiting, feeling exhausted or short of breath, blurred vision, watery eyes, trouble walking, and blood in your stools or vomit.

What must I avoid while taking prasugrel?

• Avoid activities that may magnify your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

What are the possible side effects of prasugrel?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have any of these serious side effects:

· unusual bleeding such as nosebleeds, bleeding gums, or any bleeding that will not stop;

· pale skin, fever, light bruising, purple or red spots under your skin;

· jaundice (yellowing of the skin or eyes);

· unexpected vaginal bleeding;

· feeling very weak or dizzy;

· blood in your urine or stools, black or tarry stools;

· coughing up blood or vomit that looks like coffee grounds;

· chest pain or hard feeling, pain spreading to the hand or shoulder, nausea, sweating, common ill feeling;

· sudden numbness or weakness, especially on one side of the body; or

· sudden headache, confusion, problems with vision, speech, or balance.

• Smaller serious side effects may include:

· mild headache or dizziness;

· back pain, minor chest pain;

· cough;

· nausea; or

· weary feeling.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect prasugrel?

• Till taking prasugrel, speak your doctor if you are taking a blood thinner such as warfarin (Coumadin).

• This list is not complete and there may be another drugs that can interact with prasugrel. Speak your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start using a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about prasugrel.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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