(IX ab EP i lone) Brand: Ixempra
• Do not use ixabepilone if you are pregnant. It could harm the unborn baby.
• You must not receive this medicine if you are allergic to ixabepilone, or to a medicine ingredient called Cremophor (synthetic castor oil). You may not be able to receive ixabepilone if you have severe liver malady, or severely low platelets or white blood cell counts.
• Till you receive ixabepilone, speak your doctor if you have liver malady, heart malady, nerve problems, diabetes, bone marrow suppression, or a weak immune system.
• Ixabepilone can lower blood cells that help your body fight infections. Avoid being around people who are sick or have infections. Your blood may need to be tested often. Visit your doctor regularly.
• Speak your doctor at once if you develop signs of infection, such as fever, chills, body aches, flu symptoms, pale skin, light bruising or bleeding, or sores in your mouth and throat.
• Avoid drinking alcohol during your treatment with ixabepilone.
• Ixabepilone is used to treat advanced breast cancer.
• Ixabepilone is generally given after another cancer medications have been tried without successful treatment.
• Ixabepilone may also be used for purposes not listed in this medicine guide.
• You must not receive this medicine if you are allergic to ixabepilone, or to a medicine ingredient called Cremophor (synthetic castor oil). You may not be able to receive ixabepilone if you have severe liver malady, or severely low platelets or white blood cell counts.
• To create certain you can safely receive ixabepilone, speak your doctor if you have any of these another conditions:
· liver disease;
· nerve problems (especially in your hands or feet);
· diabetes; or
· bone marrow suppression or weak immune system.
• FDA pregnancy category D. Do not use ixabepilone if you are pregnant. It could harm the unborn child. Use effective birth control, and speak your doctor if you become pregnant during treatment.
• It is not known whether ixabepilone passes into breast milk or if it could harm a nursing child. You must not breast-feed while receiving ixabepilone.
• Ixabepilone is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Ixabepilone should be given slowly, and the IV infusion can take up to 3 hours to complete.
• Ixabepilone is generally given each 3 weeks.
• About 1 hour till you receive ixabepilone, you may be given another medications to help prevent determined side effects.
• Ixabepilone can lower blood cells that help your body fight infections. This can create it easier for you to bleed from an injury or get sick from being near others who are ill. Your blood may need to be tested often. Visit your doctor regularly.
• Call your doctor for instructions if you miss an appointment for your ixabepilone injection.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Avoid being around people who are sick or have infections. Speak your doctor at once if you develop signs of infection.
• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.
• Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
• Avoid drinking alcohol during your treatment with ixabepilone.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; warmth or tingly feeling; difficulty breathing; swelling of your person, lips, tongue, or throat.
• Speak your caregivers at once if you have any of these serious side effects:
· numbness, tingling, burning pain, discomfort, or loss of feeling anywhere in your body;
· fever, chills, body aches, flu symptoms, sores in your mouth and throat;
· light bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
· pale skin, feeling light-headed or short of breath, rapid heart course, trouble concentrating;
· sudden numbness or weakness, especially on one side of the body;
· sudden severe headache, confusion, problems with vision, speech, or balance;
· pain or burning when you urinate;
· chest pain or hard feeling; or
· redness, swelling, and pain on the palms of your hands or the soles of your feet.
• Smaller serious side effects include:
· weary feeling;
· joint or muscle pain;
· hair loss;
· nausea, vomiting, stomach pain, loss of appetite;
· diarrhea or constipation; or
· problems with your fingernails or toenails.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Much drugs can interact with ixabepilone. Adown is just a partial list. Speak your doctor if you are using:
· bosentan;
· conivaptan;
· imatinib;
· isoniazid (for treating tuberculosis);
· nefazodone;
· St. John's wort;
· an antibiotic such as clarithromycin, erythromycin, rifabutin, rifampin, rifapentine, or telithromycin;
· antifungal medicine such as itraconazole, ketoconazole, miconazole, posaconazole, or voriconazole;
· a barbiturate such as butabarbital, secobarbital, pentobarbital, or phenobarbital;
· heart or blood pressure medicine such as nicardipine or quinidine;
· the hepatitis C medications boceprevir or telaprevir;
· HIV/AIDS medicine such as atazanavir, delavirdine, efavirenz, etravirine, fosamprenavir, indinavir, nelfinavir, nevirapine, ritonavir, or saquinavir;
· medicines to treat narcolepsy, such as armodafinil or modafinil; or
· seizure medicine such as carbamazepine, felbamate, oxcarbazepine, phenytoin, or primidone.
• This list is not complete and another drugs may interact with ixabepilone. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.
• Your doctor or pharmacist can provide more information about ixabepilone.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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