DEXTROMETHORPHAN AND PROMETHAZINE

(dex troe me THOR fan and pro METH a zeen) Brand: Promethazine with Dextromethorphan, Promethazine with DM

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What is the most significant information I must know about dextromethorphan?

• Call your doctor immediately if you experience uncontrollable movements of your eyes, lips, tongue, person, arms, or legs. These could be early signs of dangerous side effects.

Always ask a doctor till giving a cough or cool medication to a child. Death can occur from the misuse of cough and cool medicines in very young children.

• Do not use dextromethorphan and promethazine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take dextromethorphan and promethazine till the MAO inhibitor has cleared from your body.

• Do not use any another over-the-counter cough, cool, or allergy medicine without first asking your doctor or pharmacist. If you take determined commodity together you may accidentally take too many of one or more types of medication. Read the label of any another medication you are using to see if it contains dextromethorphan.

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

What is dextromethorphan and promethazine?

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Promethazine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body.

• The combination of dextromethorphan and promethazine used to treat cough, itching, runny nose, sneezing, and itchy or watery eyes caused by colds or allergies.

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Dextromethorphan and promethazine may also be used for purposes another than those listed in this medicine guide.

What must I discuss with my healthcare provider till taking dextromethorphan and promethazine?

• Do not use dextromethorphan and promethazine if you have asthma or another lung disease.

• Do not use a cough or cool medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a cough or cool medication till the MAO inhibitor has cleared from your body.

• Till taking dextromethorphan and promethazine, speak your doctor if you are allergic to any drugs, or if you have emphysema or chronic bronchitis. You may not be able to use this medicine, or you may need a dosage adjustment or particular trials during treatment.

• Till taking dextromethorphan and promethazine, speak your doctor if you have:

· epilepsy or other seizure disorder;

· emphysema or chronic bronchitis;

· sleep apnea (breathing stops during sleep);

· glaucoma;

· a stomach ulcer or digestive obstruction;

· bone marrow disorder;

· problems with urination;

· tall blood pressure or heart malady; or

· liver disease.

• If you have any of these conditions, you may not be able to use dextromethorphan and promethazine, or you may need a dosage adjustment or particular trials during treatment.

• FDA pregnancy category C. This medicine may be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether this medicine passes into breast milk or if it could harm an unborn child. Do not use dextromethorphan and promethazine without telling your doctor if you are breast-feeding a baby.

How must I take dextromethorphan and promethazine?

• Take this medicine exactly as it has been predesigned by your doctor. Do not use the medicine in larger amounts, or use it for longer than recommended. Follow the directions on your prescription label. Cough or cool medication is generally taken only for a short time before your symptoms clear up.

Always ask a doctor till giving cough or cool medication to a baby. Death can occur from the misuse of cough or cool medication in very young children.

• Measure the liquid form of this medication with a particular dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

• Conversation with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

• If you need to have any type of surgery, speak the surgeon onward of time if you have taken a cough medication within the past little days.

• Store dextromethorphan and promethazine at room temperature, away from heat, easy, and moisture.

What happens if I miss a dose?

• Since cough and cool medication is generally taken only as needed, you may not be on a dosing schedule. If you are taking the medicine regularly, take the missed doze as soon as you remember. If it is nearly time for your following doze, skip the missed doze and take the medication at your following regularly scheduled time. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medicine.

• Symptoms of a dextromethorphan and promethazine overdose may include feeling restless or nervous, severe drowsiness, dizziness, dry mouth, big pupils, flushing, nausea, vomiting, shallow breathing, and fainting.

What must I avoid while taking dextromethorphan and promethazine?

• This medicine can reason side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

• Avoid drinking alcohol. It can magnify some of the side effects of dextromethorphan and promethazine.

• Avoid taking diet pills, caffeine pills, or another stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with cough medication can magnify your risk of unpleasant side effects.

• Avoid using another drugs that create you sleepy (such as cool medication, sleeping pills, pain medicine, muscle relaxers, and medication for seizures, depression or anxiety).

• Do not use any another over-the-counter cough, cool, or allergy medicine without first asking your doctor or pharmacist. Dextromethorphan is contained in much medicines accessible over the counter. If you take determined commodity together you may accidentally take too many of this medication. Read the label of any another medication you are using to see if it contains dextromethorphan.

What are the possible side effects of dextromethorphan and promethazine?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using dextromethorphan and promethazine and call your doctor at once if you have any of these serious side effects:

· uncontrollable movements of your eyes, lips, tongue, person, arms, or legs;

· tremors, twitching, or uncontrolled muscle movements in your person, arms, or legs.

· severe dizziness, anxiety, restless feeling, or nervousness;

· hallucinations (seeing or hearing things);

· confusion, hallucinations; or

· slow, shallow breathing, weak pulse;

· nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or

· fever, muscle stiffness, confusion, quick or uneven heartbeat, sweating, fainting.

• Hold taking dextromethorphan and promethazine and conversation with your doctor if you have any of these smaller serious side effects:

· dizziness, drowsiness, sleepiness, or confusion;

· blurred vision, dry mouth;

· ringing in your ears;

· nausea or vomiting; or

· heighten sensitivity to sunlight.

• Side effects another than those listed here may also occur. Conversation to your doctor about any side effect that seems unusual or that is especially bothersome. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect dextromethorphan and promethazine?

• Till taking dextromethorphan and promethazine, speak your doctor if you are using any of the next drugs:

· celecoxib (Celebrex);

· cinacalcet (Sensipar);

· darifenacin (Enablex);

· imatinib (Gleevec);

· quinidine (Quinaglute, Quinidex);

· ranolazine (Ranexa)

· ritonavir (Norvir);

· sibutramine (Meridia);

· terbinafine (Lamisil);

· medicines to treat tall blood pressure;

· antidepressant medications such as amitriptyline (Elavil, Etrafon), bupropion (Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Janimine, Tofranil), paroxetine (Paxil), sertraline (Zoloft), and others.

· sedatives or anxiety medicines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion);

· phenobarbital (Luminal), amobarbital (Amytal) and secobarbital (Seconal); or

· atropine (Donnatal, and others), belladonna, clidinium (Quarzan), dicyclomine (Bentyl), glycopyrrolate (Robinul), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), methscopolamine (Pamine), and scopolamine (Transderm-Scop).

• If you are using any of these drugs, you may not be able to use dextromethorphan and promethazine, or you may need dosage adjustments or particular trials during treatment.

• There may be another drugs not listed that can affect dextromethorphan and promethazine. Speak your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start using a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist has information about dextromethorphan and promethazine written for health professionals that you may read.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

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