LURASIDONE

(loo RAS i done) Brand: Latuda

What is the most significant information I must know about lurasidone?

• Lurasidone is not for use in psychotic conditions related to dementia. Lurasidone may reason heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

• You must not use this medicine if you are allergic to lurasidone, or if you are also using ketoconazole (Extina, Ketozole, Nizoral, Xolegal) or rifampin (Rifater, Rifadin, Rifamate).

• Till you take lurasidone, speak your doctor if you have liver malady, kidney malady, heart malady, tall blood pressure, heart rhythm problems, a history of heart onslaught or stroke, tall cholesterol or triglycerides, low white blood cell (WBC) counts, seizures, diabetes, Parkinson's malady, trouble swallowing, or a history of breast cancer or suicidal thoughts.

• While you are taking lurasidone, you may be more sensitive to temperature extremes such as very hot or cool conditions. Avoid getting too cool, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercice. It is easier to become dangerously overheated and dehydrated while you are taking lurasidone.

• Lurasidone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too quick from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

• Drinking alcohol can magnify determined side effects of lurasidone.

• Stop using lurasidone and call your doctor at once if you have very stiff (rigid) muscles, tall fever, sweating, confusion, quick or pounding heartbeats, feeling like you might pass out, tremors, or twitching or uncontrollable movements of your eyes, lips, tongue, person, arms, or legs.

• There are much another drugs that can interact with lurasidone. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor. Hold a list of all your medicines and show it to any healthcare provider who treats you.

What is lurasidone?

• Lurasidone is an antipsychotic medicine. It works by changing the effects of chemicals in the brain.

• Lurasidone is used to treat schizophrenia in adults.

• Lurasidone may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking lurasidone?

• Lurasidone is not for use in psychotic conditions related to dementia. Lurasidone may reason heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

• You must not use this medicine if you are allergic to lurasidone, or if you are also using ketoconazole (Extina, Ketozole, Nizoral, Xolegal) or rifampin (Rifater, Rifadin, Rifamate).

• To create certain you can safely take lurasidone, speak your doctor if you have any of these another conditions:

· liver disease;

· kidney disease;

· heart malady, tall blood pressure, heart rhythm problems;

· a history of heart onslaught or stroke;

· tall cholesterol or triglycerides (a type of thick in the blood);

· low white blood cell (WBC) counts;

· a history of breast cancer;

· seizures or epilepsy;

· private or family history of diabetes (lurasidone may raise your blood sugar);

· a history of suicidal thoughts or actions;

· Parkinson's malady; or

· trouble swallowing.

• Lurasidone may reason you to have tall blood sugar (hyperglycemia). Conversation to your doctor if you have any signs of hyperglycemia such as heighten thirst or urination, overweening famine, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking lurasidone.

• FDA pregnancy category B. Lurasidone is not expected to harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether lurasidone passes into breast milk or if it could harm a nursing child. You must not breast-feed while using lurasidone.

• Do not give this medicine to a baby without medical advice.

How must I take lurasidone?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Lurasidone must be taken with food (at least 350 calories).

• Use lurasidone regularly to get the most benefit. Get your prescription refilled till you run out of medication completely.

• It may take different weeks till your symptoms improve. Hold using the medicine as directed and speak your doctor if your symptoms do not improve.

• Store at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include some of the serious side effects listed in this medicine guide.

What must I avoid while taking lurasidone?

• Lurasidone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

• Avoid getting up too quick from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

• Drinking alcohol can magnify determined side effects of lurasidone.

What are the possible side effects of lurasidone?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop taking lurasidone and call your doctor at once if you have a serious side effect such as:

· dizziness, fainting, quick or pounding heartbeats;

· agitation, hostility, confusion, thoughts about hurting yourself;

· seizure (convulsions);

· fever, chills, body aches, flu symptoms, sores in your mouth and throat;

· tall blood sugar (increased thirst, heighten urination, famine, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss);

· very stiff (rigid) muscles, tall fever, sweating, confusion, quick or uneven heartbeats, tremors, feeling like you might pass out;

· trouble swallowing; or

· twitching or uncontrollable movements of your eyes, lips, tongue, person, arms, or legs.

• Smaller serious side effects may include:

· drowsiness;

· feeling restless;

· nausea, diarrhea, stomach pain, loss of appetite;

· blurred vision;

· weight gain;

· breast swelling or discharge;

· missed menstrual periods; or

· decreased sex drive, impotence, or difficulty having an orgasm.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect lurasidone?

• Till you take lurasidone, speak your doctor if you regularly use another medicines that create you sleepy (such as cool or allergy medication, narcotic pain medication, sleeping pills, muscle relaxers, and medication for seizures, depression, or anxiety). They can add to sleepiness caused by lurasidone.

• Much drugs can interact with lurasidone. Adown is just a partial list. Speak your doctor if you are using:

· bosentan (Tracleer);

· conivaptan (Vaprisol);

· dexamethasone (Decadron, Hexadrol);

· imatinib (Gleevec);

· isoniazid (for treating tuberculosis);

· St. John's wort;

· an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), rifapentine (Priftin), or telithromycin (Ketek);

· antifungal medicine such as fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), or voriconazole (Vfend);

· an antidepressant such as nefazodone;

· heart or blood pressure medicine such as diltiazem (Cartia, Cardizem), nicardipine (Cardene), quinidine (Quin-G), verapamil (Calan, Covera, Isoptin, Verelan), and others;

· HIV/AIDS medication such as atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), etravirine (Intelence), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), saquinavir (Invirase), or ritonavir (Norvir, Kaletra);

· medicines to treat narcolepsy, such as armodafinil (Nuvigil) or modafinil (Progivil); or

· seizure medicine such as carbamazepine (Carbatrol, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenobarbital (Solfoton), phenytoin (Dilantin), or primidone (Mysoline).

• This list is not complete and another drugs may interact with lurasidone. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about lurasidone.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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