SILODOSIN

(SIL oh DOE sin) Brand: Rapaflo

What is the most significant information I must know about silodosin?

• You must not take silodosin if you have severe kidney or liver malady, or if you are also using ketoconazole (Extina, Ketozole, Nizoral, Xolegal), itraconazole (Sporanox), or ritonavir (Norvir).

• Do not take silodosin with another similar medicines such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), tamsulosin (Flomax), or terazosin (Hytrin).

• Silodosin may reason dizziness or fainting, especially when you first start taking it. Be careful if you drive or do anything that requires you to be alert. Avoid standing for long periods of time or becoming overheated during exercice and in hot weather. Avoid getting up too quick from a sitting or lying position, or you may feel dizzy.

• Silodosin can affect your pupils during cataract surgery. Speak your eye surgeon onward of time that you are using this medicine. Do not stop using silodosin till surgery unless your surgeon tells you to.

• There are much another drugs that can interact with silodosin. Speak your doctor about all medications you use.

What is silodosin?

• Silodosin is in a group of drugs called alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Silodosin helps slackening the muscles in the prostate and bladder neck, making it easier to urinate.

• Silodosin is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate).

• Silodosin may also be used for another purposes not listed in this medicine guide.

What must I discuss with my health care provider till taking silodosin?

• You must not take silodosin if you are allergic to it, or if you have:

· severe kidney disease;

· severe liver malady; or

· if you are also using ketoconazole (Extina, Ketozole, Nizoral, Xolegal), itraconazole (Sporanox), or ritonavir (Norvir).

• Do not take silodosin with another similar medicines such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), tamsulosin (Flomax), or terazosin (Hytrin).

• If you have liver or kidney malady or a history of prostate cancer, you may need a silodosin doze adjustment or particular trials to safely take this medication.

• Although this medicine is not for use in women, silodosin is not expected to harm an unborn child. If you are a woman using this medicine, speak your doctor if you are pregnant or breast-feeding.

• Silodosin is not for use in children.

How must I take silodosin?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Your doctor may occasionally change your doze to create certain you get the excellent results.

• Silodosin is generally taken once daily with a meal.

• Silodosin lowers blood pressure and may reason dizziness or fainting, especially when you first start taking it. Call your doctor if you have severe dizziness or feel like you might pass out.

• You may feel very dizzy when you first wake up. Be careful when standing or sitting up from a lying position.

• Your blood pressure and prostate will need to be checked often. Visit your doctor regularly.

• Some things can reason your blood pressure to get too low. This includes vomiting, diarrhea, hard sweating, heart malady, dialysis, a low-salt diet, or taking diuretics (water pills). Speak your doctor if you have a prolonged diseases that causes diarrhea or vomiting.

• Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include extreme dizziness or fainting.

What must I avoid while taking silodosin?

• Silodosin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

• To prevent dizziness, avoid standing for long periods of time or becoming overheated during exercice and in hot weather.

• Avoid getting up too quick from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

• Drinking alcohol can magnify determined side effects of silodosin.

What are the possible side effects of silodosin?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop using silodosin and call your doctor at once if you have a serious side effect such as:

· feeling like you might pass out; or

· penis erection that is painful or lasts 4 hours or longer.

• Smaller serious side effects may include:

· mild dizziness;

· headache;

· diarrhea;

· emergency ejaculation; or

· runny or stuffy nose, sore throat.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect silodosin?

• Speak your doctor about all another medications you use, especially:

· conivaptan (Vaprisol);

· imatinib (Gleevec);

· isoniazid (for treating tuberculosis);

· quinidine (Quin-G);

· an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or telithromycin (Ketek);

· an antidepressant such as nefazodone;

· antifungal medicine such as clotrimazole (Mycelex Troche) or voriconazole (Vfend);

· erectile dysfunction medication such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra);

· heart or blood pressure medicine such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nicardipine (Cardene), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others;

· HIV/AIDS medication such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), or nelfinavir (Viracept), saquinavir (Invirase); or

· medicines used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf).

• This list is not complete and there are much another drugs that can interact with silodosin. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor. Hold a list of all your medicines and show it to any healthcare provider who treats you.

Where can I get more information?

• Your pharmacist can provide more information about silodosin.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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