(PAK li TAX el PRO teen-bound) Brand: Abraxane
• You must not use paclitaxel protein-bound if you are allergic to it, or if you have a low white blood cell count.
• You may need frequent medical trials at your doctor's office to be certain this medicine is not causing deleterious effects. Your cancer treatments may be delayed based on the results of these tests.
• Paclitaxel protein-bound is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
• Paclitaxel protein-bound is used in the treatment of breast cancer and lung cancer.
• Paclitaxel protein-bound is generally given after another cancer medicines have been tried without successful treatment.
• Paclitaxel protein-bound may also be used for purposes not listed in this medicine guide.
• You must not use paclitaxel protein-bound if you are allergic to it, or if you have a low white blood cell count.
• To create certain paclitaxel protein-bound is safety for you, speak your doctor if you have:
· kidney disease;
· liver disease;
· heart malady, heart rhythm mess; or
· bone marrow suppression.
• FDA pregnancy category D. Do not use paclitaxel protein-bound if you are pregnant. It could harm the unborn child. Use effective birth control, and speak your doctor if you become pregnant during treatment.
• Use birth control to prevent pregnancy while you are receiving paclitaxel protein-bound, whether you are a man or a woman. Paclitaxel protein-bound use by either parent may reason birth defects. Follow your doctor's instructions about how long to prevent pregnancy after your treatment ends.
• It is not known whether paclitaxel protein-bound passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are receiving paclitaxel protein-bound.
• Paclitaxel protein-bound is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting.
• Paclitaxel protein-bound is generally given once each 3 weeks. Follow your doctor's dosing instructions very carefully.
• Speak your caregivers if you feel any burning, pain, or swelling near the IV needle when paclitaxel protein-bound is injected.
• You may need frequent medical trials at your doctor's office to be certain this medicine is not causing deleterious effects. Your cancer treatments may be delayed based on the results of these tests.
• Call your doctor for instructions if you miss an appointment for your paclitaxel protein-bound injection.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.
• Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
• Paclitaxel protein-bound can be deleterious if it gets in your eyes, mouth, or nose, or on your skin. If skin contact occurs, wash the area with soap and water or rinse the eyes thoroughly with plain water.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have:
· fever, swollen gums, painful mouth sores, pain when swallowing, skin sores, cool or flu symptoms, cough;
· feeling very thirsty or hot, being unable to urinate, hard sweating, or hot and dry skin;
· pale skin, light bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
· a light-headed feeling, like you might pass out;
· feeling short of breath (even with mild exertion), swelling, rapid weight gain;
· chest pain, sudden cough, wheezing, trouble breathing, quick heart course; or
· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.
• General side effects may include:
· numbness or tingly feeling;
· muscle or joint pain;
· nausea, vomiting, diarrhea; or
· hair loss.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Speak your doctor about all medicines you use, and those you start or stop using during your treatment with paclitaxel protein-bound, especially:
· bosentan;
· cimetidine;
· fluoxetine;
· gemfibrozil;
· imatinib;
· nefazodone;
· St. John's wort;
· an antibiotic--clarithromycin, erythromycin, telithromycin;
· antifungal medication--itraconazole, ketoconazole, posaconazole, voriconazole;
· heart medication--nicardipine, quinidine;
· hepatitis C medications--boceprevir, telaprevir;
· HIV/AIDS medication--atazanavir, delavirdine, efavirenz, fosamprenavir, indinavir, nelfinavir, nevirapine, ritonavir, saquinavir;
· seizure medication--carbamazepine, fosphenytoin, oxcarbazepine, phenobarbital, phenytoin, primidone; or
· tuberculosis medication--isoniazid, rifabutin, rifampin, rifapentine.
• This list is not complete. Another drugs may interact with paclitaxel protein-bound, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.
• Your doctor or pharmacist can provide more information about paclitaxel protein-bound.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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