DESMOPRESSIN (ORAL)

(DEZ mo press in) Brand: DDAVP

What is the most significant information I must know about oral desmopressin?

• It is very significant to reduce your intake of water and another fluids while you are taking desmopressin. Drinking too many water can reason your body to lose sodium, which may lead to a serious, life-threatening electrolyte imbalance.

• Fluid restriction is especially significant in children and older adults taking desmopressin. Follow your doctor's instructions about the type and amount of liquids you must drink.

• You must not use this medicine if you have severe kidney malady or if you have ever had hyponatremia (low sodium levels in your body).

• Till taking desmopressin, speak your doctor if you have heart malady, coronary artery malady, congestive heart failure, kidney malady, cystic fibrosis, tall or low blood pressure, an electrolyte imbalance, or a psychological mess that causes extreme or unusual thirst.

• To be certain desmopressin is helping your condition, your blood will need to be tested often. This will help your doctor determine how long to treat you with this medicine. Do not miss any scheduled appointments.

What is desmopressin?

• Desmopressin is a man-made form of a hormone that occurs naturally in the pituitary gland. This hormone is significant for much functions including blood flow, blood pressure, kidney function, and regulating how the body uses water.

• Desmopressin is used to treat bed-wetting, central cranial diabetes insipidus, and heighten thirst and urination caused by head surgery or head trauma.

• Desmopressin may also be used for another purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking oral desmopressin?

• You must not take this medicine if you are allergic to desmopressin, or if you have:

· severe kidney malady; or

· if you have ever had hyponatremia (low sodium levels in your body).

• Till taking desmopressin, speak your doctor if you are allergic to any medications, or if you have:

· heart malady, coronary artery disease;

· congestive heart failure;

· kidney disease;

· cystic fibrosis;

· tall or low blood pressure;

· an electrolyte imbalance; or

· a psychologic mess that causes extreme or unusual thirst.

• If you have any of these conditions, you may need a doze adjustment or particular trials to safely take desmopressin.

• FDA pregnancy category B. This medicine is not expected to harm an unborn child. Do not use desmopressin without telling your doctor if you are pregnant.

• It is not known whether desmopressin passes into breast milk, or if it could harm a nursing child. Do not use desmopressin without telling your doctor if you are breast-feeding a baby.

How must I take desmopressin?

• Take this medicine exactly as predesigned by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

• Fluid restriction is especially significant in children and older adults taking desmopressin. Follow your doctor's instructions about the type and amount of liquids you must drink.

• If you are switching from desmopressin nasal spray to desmopressin tablets, wait at least 24 hours after your recent nasal doze till you take your first tablet.

• To be certain this medicine is helping your condition, your blood will need to be tested often. This will help your doctor determine how long to treat you with desmopressin. Do not miss any scheduled appointments.

• Store the tablets at room temperature away from moisture, easy, and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. If it is nearly time for your following doze, wait before then to take the medication and skip the missed doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medicine.

• Overdose symptoms may include headache, confusion, drowsiness, rapid weight gain, or urination problems.

What must I avoid while taking desmopressin?

• Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are taking desmopressin.

What are the possible side effects of desmopressin?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop taking desmopressin and call your doctor at once if you have any of these serious side effects:

· nausea, vomiting, weakness, loss of appetite, headache, feeling restless or irritable, confusion, hallucinations, muscle pain or weakness, and/or seizure;

· feeling like you might pass out;

· swelling, weight gain; or

· dangerously tall blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

• Smaller serious side effects may include:

· headache;

· nausea, mild stomach pain;

· diarrhea; or

· warmth, redness, or tingly feeling in your face.

• This is not a complete list of side effects and others may occur. Speak your doctor about any unusual or bothersome side effect. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect desmopressin?

• Much drugs can interact with desmopressin. Adown is just a partial list. Speak your doctor if you are using:

· carbamazepine (Carbatrol, Tegretol);

· chlorpromazine (Thorazine);

· lamotrigine (Lamictal);

· oxybutynin (Ditropan, Urotrol, Oxytrol);

· vasopressin (Pitressin);

· a narcotic pain medication such as fentanyl (Actiq, Duragesic), hydrocodone (Lortab, Vicodin), oxycodone (Oxycontin), and others;

· an "SSRI" antidepressant such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft);

· a tricyclic antidepressant such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), and others;

· medication to treat erectile dysfunction, such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra);

· drugs to treat tall blood pressure or a prostate mess, such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin), tamsulosin (Flomax);

· a beta-blocker such as atenolol (Tenormin), bisoprolol (Zebeta, Ziac), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), or timolol (Blocadren); or

· an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), and others.

• This list is not complete and there may be another drugs that can interact with desmopressin. Speak your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about desmopressin.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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