(bri MOE ni deen and TIM oh lol off THAL mik) Brand: Combigan
• You must not use brimonidine and timolol ophthalmic if you have a history of asthma or chronic obstructive pulmonary malady (COPD), or a serious heart condition such as "AV block," severe heart failure, or slow heartbeats that have caused you to faint.
• Brimonidine and timolol ophthalmic must not be given to a baby younger than 2 years old.
• Brimonidine reduces the amount of fluid in the eye, which decreases pressure internal the eye.
• Timolol is a beta-blocker that also reduces pressure internal the eye.
• Brimonidine and timolol ophthalmic (for the eyes) is used to treat open-angle glaucoma or ocular hypertension (high pressure internal the eye).
• Brimonidine and timolol ophthalmic may also be used for purposes not listed in this medicine guide.
• You must not use brimonidine and timolol ophthalmic if you are allergic to it, or if you have:
· a history of asthma or chronic obstructive pulmonary malady (COPD); or
· a serious heart condition such as "AV block," severe heart failure, or slow heartbeats that have caused you to faint.
• To create certain brimonidine and timolol ophthalmic is safety for you, speak your doctor if you have:
· congestive heart failure, coronary artery malady, history of stroke or blood clot;
· tall or low blood pressure, circulation problems (such as Raynaud's syndrome);
· depression;
· diabetes (using brimonidine and timolol ophthalmic may create it harder for you to speak when you have low blood sugar);
· a thyroid disorder;
· any allergies;
· myasthenia gravis; or
· a history of glaucoma or heighten pressure internal your eye.
• FDA pregnancy category C. It is not known whether brimonidine and timolol ophthalmic will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.
• Timolol ophthalmic can pass into breast milk and may harm a nursing child. You must not breast-feed while using this medicine.
• Do not give this medication to a baby without medical advice.
• Follow all directions on your prescription label. Do not use this medication in larger or less amounts or for longer than recommended.
• Do not use this medicine while wearing contact lenses. Brimonidine and timolol ophthalmic may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medication till putting in your contact lenses.
• Wash your hands till using the eye drops.
• To apply the eye drops:
· Tilt your head back slightly and pull down your lower eyelid to make a little pocket. Keep the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.
· Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the internal corner of the eye for about 1 minute, to hold the liquid from draining into your tear duct.
· Use only the number of drops your doctor has predesigned. If you use more than one drop, wait about 5 minutes between drops.
· Wait at least 10 minutes till using any another eye drops your doctor has prescribed.
• Do not touch the tip of the eye dropper or seat it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.
• Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.
• Speak your doctor right away if you have any eye injury or infection, or if you need to have any type of surgery, especially eye surgery.
• Store at room temperature away from moisture and heat. Do not freeze. Hold the bottle tightly closed when not in use.
• Use the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not use extra medication to create up the missed dose.
• An overdose of brimonidine and timolol ophthalmic is not expected to be dangerous. Search abnormal medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.
• This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
• Do not use another eye medications unless your doctor tells you to.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have:
· slow or uneven heart rate;
· pounding heartbeats or fluttering in your chest;
· shallow breathing, feeling like you might pass out;
· severe swelling, redness, or discomfort in or near your eye;
· eye pain or heighten watering; or
· numbness or tingly feeling in your hands or feet.
• General side effects may include:
· drowsiness, weary feeling;
· mild itching, redness, or irritation of your eyes; or
· mild stinging or burning when using the eye drops.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Using this medication with another drugs that create you sleepy or slow your breathing can magnify these effects. Ask your doctor till using brimonidine and timolol ophthalmic with a sleeping pill, narcotic pain medication, muscle relaxer, or medication for anxiety, depression, or seizures.
• Speak your doctor about all medicines you use, and those you start or stop using during your treatment with brimonidine and timolol ophthalmic, especially:
· digoxin, digitalis;
· reserpine;
· an antidepressant--amitriptyline, bupropion, clomipramine, desipramine, doxepin, duloxetine, fluoxetine, imipramine, nortriptyline, paroxetine;
· an MAO inhibitor--isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, tranylcypromine;
· a beta blocker--atenolol, carvedilol, labetalol, metoprolol, nadolol, nebivolol, propranolol, sotalol, and others; or
· heart or blood pressure medicine--amlodipine, diltiazem, methyldopa, nifedipine, quinidine, verapamil, and others.
• This list is not complete. Another drugs may interact with brimonidine and timolol ophthalmic, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.
• Your pharmacist can provide more information about brimonidine and timolol ophthalmic.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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