(vin OR el been) Brand: Navelbine
• You must not use this medicine if you are allergic to it, or if you have severely low white blood cell counts.
• Do not use vinorelbine if you are pregnant. It could harm the unborn child. Use effective birth control, and speak your doctor if you become pregnant during treatment.
• Till you receive vinorelbine, speak your doctor if you have liver malady, bone marrow suppression, a nerve mess, or if you have received radiation therapy or another cancer treatments.
• Vinorelbine is sometimes used in combination with another cancer medications.
• Speak your caregivers if you feel any burning, pain, or swelling near the IV needle when vinorelbine is injected.
• Vinorelbine can lower blood cells that help your body fight infections. Avoid being around people who have colds, the flu, or another contagious illnesses. Your blood will need to be tested on a regular basis. Do not miss any scheduled appointments. Contact your doctor at once if you develop signs of infection.
• Do not receive a "live" vaccine while you are being treated with vinorelbine, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you.
• Vinorelbine is cancer medicine that interferes with the growth of cancer cells and slows their spread in the body.
• Vinorelbine is used to treat non-small cell lung cancer.
• Vinorelbine is sometimes used in combination with another cancer medications.
• Vinorelbine may also be used for another purposes not listed in this medicine guide.
• You must not use this medicine if you are allergic to it, or if you have severely low white blood cell counts.
• If you have any of these another conditions, you may need a doze adjustment or particular trials to safely use this medication:
· liver disease;
· bone marrow suppression;
· a nerve mess; or
· if you have received radiation therapy or another cancer treatments.
• FDA pregnancy category D. Vinorelbine can reason harm to an unborn child or reason birth defects. Before you receive vinorelbine, speak your doctor if you are pregnant. Use an effective form of birth control, and speak your doctor if you become pregnant during treatment.
• It is not known whether vinorelbine passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are being treated with vinorelbine.
• Vinorelbine is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting. The medication should be given slowly through an IV infusion.
• Vinorelbine is generally given once each 7 days. You may also receive the medicine once each 6 weeks. Follow your doctor's instructions.
• Speak your caregivers if you feel any burning, pain, or swelling near the IV needle when the medication is injected.
• Vinorelbine can lower the blood cells that help your body fight infections. This can create it easier for you to bleed from an injury or get sick from being near others who are ill. To be certain your blood cells do not get too low, your blood will need to be tested on a regular basis. Your cancer treatments may be delayed based on the results of these trials. Do not miss any scheduled visits to your doctor.
• Call your doctor for instructions if you miss an appointment for your vinorelbine injection.
• Search abnormal medical attention if you think you have received too many of this medicine.
• Overdose symptoms may include white patches or sores in your mouth or throat, painful swallowing, heartburn, severe constipation, and stomach pain.
• Avoid being around people who have colds, the flu, or another contagious illnesses. Contact your doctor at once if you develop signs of infection.
• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.
• Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
• Do not receive a "live" vaccine while you are being treated with vinorelbine, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you. Live vaccines include measles, mumps, rubella (MMR), oral polio, chickenpox (varicella), BCG (Bacillus Calmette and Guérin), and nasal flu vaccine.
• Conversation to your doctor about ways to avoid constipation while being treated with vinorelbine.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have a serious side effect such as:
· signs of infection such as fever, chills, flu symptoms, mouth and throat ulcers, rapid heart course, rapid and shallow breathing, fainting;
· cough, bronchospasm (wheezing, chest tightness, trouble breathing);
· severe constipation, stomach pain, bloody or black stools;
· pale skin, feeling light-headed or short of breath, rapid heart course, trouble concentrating;
· light bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
· numbness, burning, pain, or tingly feeling;
· problems with vision, hearing, speech, balance, or daily activities;
· chest pain or hard feeling, pain spreading to the hand or shoulder, nausea, sweating, common ill feeling; or
· pain, burning, redness, swelling, or skin changes where the IV needle was placed.
• Smaller serious side effects may include:
· temporary hair loss;
· jaw pain, joint or muscle pain;
· tumor pain;
· weight loss;
· nausea, vomiting, diarrhea, loss of appetite; or
· feeling dizzy, weak, or tired.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Speak your doctor about all another medications you use, especially:
· conivaptan;
· diclofenac;
· imatinib;
· isoniazid (for treating tuberculosis);
· an antibiotic such as clarithromycin, dalfopristin/quinupristin, erythromycin, or telithromycin;
· antifungal medicine such as clotrimazole, itraconazole, ketoconazole, or voriconazole;
· an antidepressant such as nefazodone;
· heart or blood pressure medicine such as diltiazem, felodipine, nifedipine, verapamil and others;
· cancer medicines such as cisplatin, carboplatin, mitomycin, or oxaliplatin;
· HIV/AIDS medication such as atazanavir, delavirdine, fosamprenavir, indinavir, nelfinavir, saquinavir or ritonavir (Norvir).
• This list is not complete and there may be another drugs that can interact with vinorelbine. Speak your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start a new medicine without telling your doctor.
• Your doctor or pharmacist can provide more information about vinorelbine.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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