CARBOPLATIN

(KAR boe PLA tin) Brand: Paraplatin

What is the most significant information I must know about carboplatin?

Carboplatin is a cancer medicine used in chemotherapy combinations to treat ovarian cancer.

• You must not receive carboplatin if you have severe bleeding or bone marrow suppression.

Carboplatin can harm your kidneys, and this effect is heighten when you also use determined another medicines deleterious to the kidneys. Till you receive carboplatin, speak your doctor about all another medications you use. Much another drugs (including some over-the-counter medicines) can be deleterious to the kidneys.

Carboplatin can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).

What is carboplatin?

Carboplatin is a cancer medicine that interferes with the growth of cancer cells and slows their growth and spread in the body.

Carboplatin is used together with another cancer medications to treat ovarian cancer.

Carboplatin may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till receiving carboplatin?

• You must not receive this medicine if you are allergic to carboplatin or similar medications such as oxaliplatin (Eloxatin) or cisplatin (Platinol). You must not receive carboplatin if you have severe bleeding or bone marrow suppression.

• To create certain carboplatin is safety for you, speak your doctor if you have:

· liver disease;

· kidney disease;

· a weak immune system; or

· if you have received carboplatin in the past.

• FDA pregnancy category D. Do not use carboplatin if you are pregnant. It could harm the unborn child. Use effective birth control, and speak your doctor if you become pregnant during treatment.

• It is not known whether carboplatin passes into breast milk or if it could harm a nursing child. You must not breast-feed while being treated with carboplatin.

How is carboplatin given?

Carboplatin is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting.

Carboplatin is generally given once each 4 weeks. Follow your doctor's instructions.

• You may be given another medications to prevent nausea or vomiting while you are receiving carboplatin.

Carboplatin can lower blood cells that help your body fight infections and help your blood to clot. This can create it easier for you to bleed from an injury or get sick from being near others who are ill. Your blood may need to be tested often. Your kidney and liver function may also need to be tested.

• You may need to receive blood transfusions while you are being treated with carboplatin.

What happens if I miss a dose?

• Contact your doctor if you miss an appointment for your carboplatin injection.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while using carboplatin?

• Avoid being around people who are sick or have infections. Speak your doctor at once if you develop signs of infection.

Carboplatin can reason side effects that may impair your vision. Be careful if you drive or do anything that requires you to be able to see clearly.

• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.

Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.

What are the possible side effects of carboplatin?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have:

· pale skin, feeling light-headed or short of breath, rapid heart course, trouble concentrating;

· light bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;

· fever, chills, body aches, flu symptoms, sores in your mouth and throat;

· severe or ongoing vomiting;

· stomach pain, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

· numbness or tingly feeling in your hands or feet;

· hearing or vision problems;

· skin changes where the medication was injected; or

· low magnesium (confusion, uneven heart course, jerking muscle movements, muscle weakness or limp feeling).

• General side effects may include:

· nausea, vomiting, loss of appetite;

· weary feeling;

· temporary hair loss; or

· pain, swelling or redness where the medication was injected.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect carboplatin?

Carboplatin can harm your kidneys. This effect is heighten when you also use determined another medicines, including: antivirals, chemotherapy, injected antibiotics, medication for bowel disorders, medication to prevent organ transplant rejection, and some pain or arthritis medicines (including aspirin, Tylenol, Advil, and Aleve).

• This list is not complete. Another drugs may interact with carboplatin, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.

Where can I get more information?

• Your doctor or pharmacist can provide more information about carboplatin.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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