(vin KRIS teen LYE poe some) Brand: Marqibo
• You must not use this medicine if you have Charcot-Marie-Tooth syndrome or another conditions that reason hurt to myelin (protective covering of the nerves in your brain and spinal cord).
• Vincristine liposome is cancer medicine that interferes with the growth of cancer cells and slows their spread in the body.
• Vincristine liposome is used to treat a type of blood cancer called Philadelphia chromosome negative acute lymphoblastic leukemia (ALL).
• Vincristine liposome is generally given after at least two another cancer medications have been tried without success.
• Vincristine liposome may also be used for purposes not listed in this medicine guide.
• You must not use this medicine if you are allergic to vincristine, or if you have Charcot-Marie-Tooth syndrome or another conditions that reason hurt to myelin (protective covering of the nerves in your brain and spinal cord).
• To create certain vincristine liposome is safety for you, speak your doctor if you have:
· liver disease;
· a nerve-muscle mess such as myasthenia gravis, ALS (Lou Gehrig's disease), multiple sclerosis, or muscular dystrophy;
· peripheral vascular malady such as Raynaud's syndrome;
· a bowel obstruction called paralytic ileus;
· coronary artery disease.
• FDA pregnancy category D. Vincristine liposome can reason harm to an unborn child or reason birth defects. Before you receive vincristine liposome, speak your doctor if you are pregnant. Use effective birth control to avoid pregnancy during your treatment with vincristine liposome. Follow your doctor's instructions about how long to prevent pregnancy after your treatment ends.
• Vincristine liposome can pass into breast milk and may harm a nursing child. You must not breast-feed while using this medicine.
• Vincristine liposome is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting. The medication should be given slowly through an IV infusion.
• Vincristine liposome can reason severe constipation. You may be given medicine to prevent constipation while you are receiving this medication. Use all medications as directed by your doctor.
• Speak your caregivers if you feel any burning, pain, or swelling near the IV needle when the medication is injected.
• Vincristine liposome can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.
• Call your doctor for instructions if you miss an appointment for your vincristine liposome injection.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
• Avoid being around people who have colds, the flu, or another contagious illnesses. Contact your doctor at once if you develop signs of infection.
• Do not receive a "live" vaccine while using vincristine liposome, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.
• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.
• Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Call your doctor at once if you have:
· severe constipation, severe cramps;
· pale skin, feeling light-headed or short of breath, rapid heart course, feeling very weak or tired;
· numbness, tingling, or burning pain in your hands or feet;
· fever, swollen gums, painful mouth sores, pain when swallowing, skin sores, cool or flu symptoms, cough, trouble breathing;
· light bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
· lower back pain, blood in your urine, few or no urinating;
· tingly feeling near your mouth, muscle weakness, tightness, or contraction, overactive reflexes;
· quick or slow heart course, weak pulse, confusion, fainting; or
· nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
• General side effects may include:
· diarrhea, constipation,
· nausea, loss of appetite; or
· sleep problems (insomnia).
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Speak your doctor about all medicines you use, and those you start or stop using during your treatment with vincristine liposome, especially:
· clozapine, conivaptan, deferiprone, natalizumab, nefazodone; or
· an antibiotic--clarithromycin, erythromycin, telithromycin; antifungal medication--itraconazole, ketoconazole, posaconazole, voriconazole; HIV/AIDS medication--atazanavir, delavirdine, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir; hepatitis C medications--boceprevir, telaprevir.
• This list is not complete. Another drugs may interact with vincristine liposome, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Not all possible interactions are listed in this medicine manual.
• Your doctor or pharmacist can provide more information about vincristine liposome.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.