DEFERIPRONE

(de FER i prone) Brand: Ferriprox

What is the most significant information I must know about deferiprone?

Do not use deferiprone if you are pregnant. It could harm the unborn child.

• You must not use deferiprone if you are allergic to it.

• Till taking deferiprone, speak your doctor if you have kidney or liver malady, congestive heart failure, a heart rhythm mess, an electrolyte imbalance, a weak immune system, a history of Long QT syndrome, or if you take a diuretic (water pill).

Deferiprone can lower blood cells that help your body fight infections. Your blood will need to be tested weekly while you are taking this medicine. Your treatments may be delayed based on the results of these trials. Visit your doctor regularly.

• Speak your doctor about all another medicines you use, especially drugs that weaken the immune system, such as cancer medication, steroids, and medicines to prevent organ transplant rejection.

• Serious and sometimes fatal infections may occur during treatment with deferiprone. Stop using this medication and call your doctor right away if you have signs of infection such as: fever, chills, body aches, flu symptoms, or sores in your mouth and throat.

What is deferiprone?

Deferiprone binds to iron and removes it from the blood stream.

Deferiprone is used to treat iron overload caused by blood transfusions.

Deferiprone may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking deferiprone?

• You must not use deferiprone if you are allergic to it.

• To create certain you can safely take deferiprone, speak your doctor if you have any of these another conditions:

· kidney disease;

· liver disease;

· congestive heart failure;

· a heart rhythm disorder;

· an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);

· a weak immune system;

· a history of Long QT syndrome; or

· if you take a diuretic (water pill).

• FDA pregnancy category D. Do not use deferiprone if you are pregnant. It could harm the unborn child. Use effective birth control, and speak your doctor if you become pregnant during treatment.

• It is not known whether deferiprone passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are taking deferiprone.

• Do not give this medication to a baby without medical advice.

How must I take deferiprone?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your doze to create certain you get the excellent results.

Deferiprone is generally taken 3 times for day. Take the first daily doze every morning, the second doze at mid-day, and the third doze in the evening.

Deferiprone may be taken with food if it upsets your stomach.

Deferiprone may reason your urine to turn a reddish-brown color. This side effect is generally not deleterious. Call your doctor if you also have upper stomach pain, clay-colored stools, or jaundice (yellowing of your skin or the whites of your eyes).

Deferiprone can lower blood cells that help your body fight infections. Your blood will need to be tested weekly while you are taking this medicine. Your treatments may be delayed based on the results of these trials. Visit your doctor regularly.

• Speak your doctor if you have any changes in your weight.

• Store at room temperature, away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose symptoms may include vision problems, drowsiness, weakness, uncontrolled movement in your hands, or limp feeling.

What must I avoid while taking deferiprone?

• Avoid taking an antacid or mineral supplement within 4 hours till or 4 hours after you take deferiprone.

• Avoid taking an herbal supplement containing milk thistle while you are taking deferiprone.

• Do not use another iron chelating medicines such as deferasirox (Exjade) or deferoxamine (Desferal), unless your doctor has told you to.

What are the possible side effects of deferiprone?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Serious and sometimes fatal infections may occur during treatment with deferiprone. Stop using this medication and call your doctor right away if you have signs of infection such as: fever, chills, body aches, flu symptoms, or sores in your mouth and throat.

• Stop using deferiprone and call your doctor at once if you have a serious side effect such as:

· pounding heartbeats or fluttering in your chest;

· feeling like you might pass out; or

· seizure (convulsions).

• Smaller serious side effects may include:

· mild stomach pain or nausea;

· vomiting, diarrhea;

· joint pain, back pain;

· heighten appetite; or

· headache.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect deferiprone?

• Speak your doctor about all another medicines you use, especially drugs that weaken the immune system, such as cancer medication, steroids, and medicines to prevent organ transplant rejection.

• This list is not complete and another drugs may interact with deferiprone. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about deferiprone.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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