ISOSORBIDE MONONITRATE

(EYE soe SOR bide MON oh NYE trate) Brand: Imdur, ISMO, Monoket

What is the most significant information I must know about isosorbide mononitrate?

• Do not use isosorbide mononitrate if you are taking sildenafil (Viagra, Revatio). Serious, life-threatening side effects can occur if you take isosorbide mononitrate while you are using sildenafil.

• You must not use this medicine if you are allergic to isosorbide mononitrate, isosorbide dinitrate, (Isordil, Dilatrate, Isochron), or nitroglycerin, or if you have early signs of a heart onslaught (chest pain or hard feeling, pain spreading to the hand or shoulder, nausea, sweating, common ill feeling).

• Till taking isosorbide mononitrate, speak your doctor if you have congestive heart failure, low blood pressure, or kidney disease.

• Isosorbide mononitrate can reason severe headaches, especially when you first start using it. These headaches may gradually become smaller severe as you continue to use the medicine. Do not stop taking isosorbide mononitrate. Ask your doctor till using any headache pain medication.

• Isosorbide mononitrate will not treat an angina onslaught that has already begun.

• Use isosorbide mononitrate regularly to prevent an angina onslaught. Get your prescription refilled till you run out of medication completely.

• Do not stop taking isosorbide mononitrate suddenly. Stopping suddenly could reason a severe angina attack.

What is isosorbide mononitrate?

• Isosorbide mononitrate is in a group of drugs called nitrates. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.

• Isosorbide mononitrate is used to prevent angina attacks (chest pain).

• Isosorbide mononitrate will not treat an angina onslaught that has already begun.

• Isosorbide mononitrate may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking isosorbide mononitrate?

• Do not use isosorbide mononitrate if you are taking sildenafil (Viagra, Revatio). A dangerous drug interaction could occur, leading to serious side effects.

• To create certain you can safely take isosorbide mononitrate, speak your doctor if you have any of these another conditions:

· congestive heart failure;

· low blood pressure; or

· kidney disease.

• FDA pregnancy category C. It is not known whether isosorbide mononitrate will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• It is not known whether isosorbide mononitrate passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

• Isosorbide mononitrate can reason severe headaches, especially when you first start using it. These headaches may gradually become smaller severe as you continue to use isosorbide mononitrate. Do not stop taking the medicine. Ask your doctor till using any headache pain medication.

How must I take isosorbide mononitrate?

• Take exactly as predesigned by your doctor. Do not take in larger or less amounts or for longer than recommended. Follow the directions on your prescription label.

• Your doctor may occasionally change your doze to create certain you get the excellent results.

• Not all brands and forms of isosorbide mononitrate are taken the same number of times for day. You may need to take the medicine only once daily, in the morning after getting out of bed. Or you may need a second doze later in the day. Follow your doctor's dosing instructions very carefully.

• If possible, try to rest or remain seated when you use this medicine. Isosorbide mononitrate can reason dizziness or fainting.

• Take this medicine with at least 4 ounces of water or another liquid.

• Do not crush, chew, or interrupt an extended-release tablet. Swallow the pill intact. Breaking the pill may reason too many of the drug to be released at one time.

• This medicine can reason unusual results with determined medical trials. Speak any doctor who treats you that you are using isosorbide mononitrate.

• Conditions that may reason very low blood pressure include: vomiting, diarrhea, hard sweating, heart malady, dialysis, a low salt diet, or taking diuretics (water pills). Speak your doctor if you have a prolonged diseases that causes diarrhea or vomiting.

• Use isosorbide mononitrate regularly to prevent an angina onslaught. Get your prescription refilled till you run out of medication completely.

• Do not stop taking isosorbide mononitrate suddenly. Stopping suddenly could reason a severe angina attack.

• Do not change brands of isosorbide mononitrate without the approval of your doctor.

• Store at room temperature away from moisture, heat, and easy. Hold the bottle tightly closed when not in use.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. An overdose of isosorbide mononitrate can be fatal.

• Overdose symptoms may include a severe throbbing headache, fever, confusion, dizziness or spinning sensation, quick or pounding heartbeats, vision problems, nausea, vomiting, stomach pain, bloody diarrhea, trouble breathing, sweating, cool or clammy skin, feeling light-headed, fainting, and seizure (convulsions).

What must I avoid while taking isosorbide mononitrate?

• This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

• Avoid getting up too quick from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

• Drinking alcohol can magnify determined side effects of isosorbide mononitrate.

What are the possible side effects of isosorbide mononitrate?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have a serious side effect such as:

· quick, slow, pounding, or uneven heart rate;

· feeling like you might pass out;

· trouble breathing, blue-colored skin, weary feeling; or

· worsening angina pain.

• Smaller serious side effects may include:

· headache, mild dizziness;

· warmth, redness, or tingling under your skin;

· nausea, vomiting, constipation, diarrhea;

· pain or stiffness in joints or muscles;

· hot flashes; or

· dry mouth.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect isosorbide mononitrate?

• Speak your doctor about all another medications you use, especially:

· blood pressure medication;

· dihydroergotamine (D.H.E. 45, Migranal) or ergotamine (Ergomar, Cafergot, and others);

· an erectile dysfunction medicine such as tadalafil (Cialis) or vardenafil (Levitra);

· a beta blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;

· heart or blood pressure medication such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide), diltiazem (Cartia, Cardizem), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others.

• This list is not complete and another drugs may interact with isosorbide mononitrate. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about isosorbide mononitrate.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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