HYDROCODONE AND IBUPROFEN

(hye dro KOE done and eye byoo PRO fen) Brand: Ibudone, Reprexain, Vicoprofen

What is the most significant information I must know about hydrocodone and ibuprofen?

• This medication may reason life-threatening heart or circulation problems such as heart onslaught or stroke, especially if you use it long term. Do not use hydrocodone and ibuprofen just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

• Get abnormal medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

• This medication may also reason serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking hydrocodone and ibuprofen, especially in older adults.

• Call your doctor at once if you have symptoms of stomach bleeding such as black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.

• Ask a doctor or pharmacist till using any cool, allergy, or pain medicine. Much medicines accessible over the counter contain aspirin or another medicines similar to hydrocodone and ibuprofen (such as ibuprofen, ketoprofen, or naproxen). Taking determined commodity together can reason you to get too many of this type of medicine. Check the label to see if a medication contains naproxen, aspirin, ibuprofen, ketoprofen, or naproxen.

• Hydrocodone may be habit-forming and should be used only by the face for whom it was prescribed. Hold the medicine in a secure seat where others can't get to it.

• Avoid drinking alcohol. It may magnify your risk of stomach bleeding while taking ibuprofen.

What is hydrocodone and ibuprofen?

• Hydrocodone is an opioid pain medicine. An opioid is sometimes called a narcotic.

• Ibuprofen is a non steroidal anti inflammatory drug (NSAID). This medication works by reducing substances in the body that reason pain, fever, and inflammation.

• The combination of hydrocodone and ibuprofen is used short-term to relieve severe pain. This medicine is not for treating arthritis pain.

• Hydrocodone and ibuprofen may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking hydrocodone and ibuprofen?

• You must not use this medicine if you are allergic to hydrocodone or ibuprofen (Advil, Motrin), or another NSAIDs such as Aleve, Naprosyn, Celebrex, Arthrotec, Cataflam, Voltaren, Indocin, Mobic, and others.

• Do not use hydrocodone and ibuprofen just till or after heart bypass surgery (coronary artery bypass graft, or CABG).

• This medication may reason life-threatening heart or circulation problems such as heart onslaught or stroke, especially if you use it long term.

• To create certain you can safely take hydrocodone and ibuprofen, speak your doctor if you have any of these another conditions:

· heart malady, congestive heart failure, tall blood pressure, or a history of heart onslaught, stroke, or blood clot;

· asthma or another breathing disorders;

· liver or kidney disease;

· a history of head injury or brain tumor;

· stomach or intestinal mess, history of stomach ulcer or bleeding;

· underactive thyroid, Addison's malady or another adrenal gland disorder;

· curvature of the spine;

· an enlarged prostate or problems with urination; or

· mental diseases or a history of drug or alcohol addiction.

• Hydrocodone may be habit forming and must be used only by the face for whom it was predesigned. Never share hydrocodone and ibuprofen with other face, especially somebody with a history of drug abuse or addiction. Hold the medicine in a seat where others can't get to it.

• FDA pregnancy category C. Hydrocodone may reason breathing problems or addiction/withdrawal symptoms in a newborn. Taking ibuprofen during the recent 3 months of pregnancy may harm the unborn baby. Do not take hydrocodone and ibuprofen during pregnancy unless your doctor has told you to.

• It is not known whether hydrocodone and ibuprofen passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are using hydrocodone and ibuprofen.

• Older adults may be more likely to have side effects from this medicine.

How must I take hydrocodone and ibuprofen?

• Take exactly as predesigned. Never take hydrocodone and ibuprofen in larger amounts, or for longer than recommended by your doctor. Follow the directions on your prescription label. Speak your doctor if the medication seems to stop working as well in relieving your pain.

• If you need surgery, speak the surgeon onward of time that you are using hydrocodone and ibuprofen. You may need to stop using the medication for a short time.

• Store at room temperature away from moisture and heat.

• Hold track of the amount of medication used from every new bottle. Hydrocodone and ibuprofen is a drug of abuse and you must be aware if anyone is using your medication improperly or without a prescription.

What happens if I miss a dose?

• Since hydrocodone and ibuprofen is taken as needed, you may not be on a dosing schedule. If you are taking the medicine regularly, take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222. An overdose of hydrocodone and ibuprofen can be fatal.

• Overdose symptoms may include extreme drowsiness, nausea, vomiting, dark urine, jaundice (yellowing of the skin or eyes), black or bloody stools, coughing up blood, urinating smaller than normal or not at all, confusion, ringing in your ears, pinpoint pupils, weak pulse, slow heart course, blue lips, shallow breathing, or fainting.

What must I avoid while taking hydrocodone and ibuprofen?

• This medicine may impair your thinking or reactions. Avoid driving or operating machinery before you know how hydrocodone and ibuprofen will affect you.

• Ask a doctor or pharmacist till using any cool, allergy, or pain medicine. Much medicines accessible over the counter contain aspirin or another medicines similar to ibuprofen (such as ketoprofen or naproxen). Taking determined commodity together can reason you to get too many of this type of medicine. Check the label to see if a medication contains naproxen, aspirin, ibuprofen, ketoprofen, or naproxen.

• Avoid drinking alcohol. It may magnify your risk of stomach bleeding while taking ibuprofen.

What are the possible side effects of hydrocodone and ibuprofen?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Stop using hydrocodone and ibuprofen and call your doctor at once if you have a serious side effect such as:

· sudden numbness or weakness, sudden severe headache, confusion, problems with vision or speech;

· chest pain, sudden cough, wheezing, rapid breathing, coughing up blood;

· pain, swelling, warmth, or redness in one or both legs;

· bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

· swelling or rapid weight gain;

· shallow breathing, slow heartbeat;

· light bruising or bleeding, feeling like you might pass out;

· nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

· fever, chills, headache, neck stiffness, heighten sensitivity to easy, purple spots on the skin, and/or seizure (convulsions); or

· severe skin reaction -- fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.

• Smaller serious side effects may include:

· headache, dizziness, drowsiness;

· mild nausea, vomiting, upset stomach, constipation, diarrhea;

· blurred vision; or

· dry mouth.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect hydrocodone and ibuprofen?

• Till using hydrocodone and ibuprofen, speak your doctor if you regularly use another medicines that create you sleepy (such as cool or allergy medication, sedatives, narcotic pain medication, sleeping pills, muscle relaxers, and medication for seizures, depression, or anxiety). They can add to sleepiness caused by hydrocodone and ibuprofen.

• Speak your doctor about all another medicines you use, especially:

· lithium (Eskalith, Lithobid);

· methotrexate (Rheumatrex, Trexall);

· antidepressants such as amitriptyline (Elavil, Vanatrip) or imipramine (Tofranil);

· an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate);

· aspirin or another NSAIDs, such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch), indomethacin (Indocin), meloxicam (Mobic), and others;

· heart or blood pressure medicine such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others;

· a bronchodilator (such as Atrovent, Spiriva), diuretics (water pills), steroid medicines, or blood thinners;

· an injected narcotic medicine such as pentazocine (Talwin), butorphanol (Stadol), or nalbuphine Nubain);

· atropine (Atreza, Sal-Tropine), belladonna (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), or scopolamine (Transderm Scop); or

· bowel or bladder medicines such as darifenacin (Enablex), solifenacin (Vesicare), dicyclomine (Bentyl), and others.

• This list is not complete and another drugs may interact with hydrocodone and ibuprofen. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about hydrocodone and ibuprofen.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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