CEVIMELINE

(se vi ME leen) Brand: Evoxac

What is the most significant information I must know about cevimeline?

• Do not take this medicine if you are allergic to cevimeline, or if you have untreated or uncontrolled asthma, glaucoma, or an eye condition called iritis or uveitis.

• Till taking cevimeline, speak your doctor if you have heart malady, heart rhythm mess, angina (chest pain), or a history of heart onslaught, tall blood pressure (hypertension), asthma or another breathing mess, or a history of kidney or gall stones.

• Cevimeline can reason side effects that may impair your vision, especially at night. Be careful if you drive or do anything that requires you to be able to see clearly.

• Avoid becoming overheated or dehydrated during exercice and in hot weather. Cevimeline may reason overweening sweating and you may get dehydrated more easily while taking this medicine. Follow your doctor's instructions about the type and amount of liquids you must drink.

What is cevimeline?

• Cevimeline increases the secretions of the saliva and sweat glands in the body.

• Cevimeline is used to treat dry mouth in people with Sjogren's Syndrome.

• Cevimeline may also be used for another purposes not listed in this medicine guide.

What must I speak my healthcare provider till taking cevimeline?

• Do not take this medicine if you are allergic to cevimeline, or if you have:

· untreated or uncontrolled asthma;

· glaucoma; or

· an eye condition called iritis or uveitis.

• Till taking cevimeline, speak your doctor if you are allergic to any drugs, or if you have:

· heart malady, heart rhythm mess, angina (chest pain), or a history of heart attack;

· tall blood pressure (hypertension);

· asthma, chronic bronchitis, or chronic obstructive pulmonary malady (COPD); or

· a history of kidney stones or gallstones.

• If you have any of these conditions, you may need a doze adjustment or particular trials to safely take cevimeline.

• FDA pregnancy category C. This medicine may be deleterious to an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether cevimeline passes into breast milk or if it could harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take cevimeline?

• Take this medicine exactly as it was predesigned for you. Do not take the medicine in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

• Take this medicine with a full glass of water.

• Cevimeline is generally taken three times a day. Follow your doctor's instructions.

• Store cevimeline at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. If it is nearly time for your following doze, skip the missed doze and take the medication at your following regularly scheduled time. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medicine.

• Overdose symptoms may include headache, blurred vision, watery eyes, confusion, sweating, tremors or shaking, nausea, vomiting, diarrhea, stomach pain, trouble breathing, and quick, slow, or uneven heart rate.

What must I avoid while taking cevimeline?

• Cevimeline can reason side effects that may impair your vision, especially at night. Be careful if you drive or do anything that requires you to be able to see clearly.

• Avoid becoming overheated or dehydrated during exercice and in hot weather. Cevimeline may reason overweening sweating and you may get dehydrated more easily while taking this medicine. Follow your doctor's instructions about the type and amount of liquids you must drink.

What are the possible side effects of cevimeline?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Stop taking cevimeline and call your doctor at once if you have any of these serious side effects:

· shortness of breath, wheezing, or tightness in your chest;

· chest pain, uneven heart rate;

· attacks of severe stomach pain on the right side, extending up to your shoulder (sometimes worse after meals);

· nausea and vomiting, bloating, fever, chills, and jaundice (yellowing of the skin or eyes);

· swelling in your hands or feet;

· eye pain or drainage;

· fever, ear ache, flu symptoms; or

· white patches or sores internal your mouth or on your lips.

• Smaller serious side effects may include:

· blurred vision, dry eyes;

· overweening sweating or salivating, drooling;

· runny or stuffy nose;

· nausea, diarrhea, constipation, loss of appetite;

· dry mouth;

· muscle pain;

· vaginal itching or discharge;

• This is not a complete list of side effects and others may occur. Speak your doctor about any unusual or bothersome side effect. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect cevimeline?

• Till taking cevimeline, speak your doctor if you are using any of the next drugs:

· amiodarone (Cordarone, Pacerone);

· cimetidine (Tagamet);

· cyclosporine (Gengraf, Neoral, Sandimmune);

· metronidazole (Flagyl, Protostat);

· antibiotics such as azithromycin (Zithromax), ciprofloxacin (Cipro), clarithromycin (Biaxin), erythromycin (E-Mycin, E.E.S., Ery-Tab, Erythrocin), itraconazole (Sporanox), or ketoconazole (Nizoral);

· antidepressants such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft);

· asthma medicines such as albuterol (Proventil, Ventolin, others), bitolterol (Tornalate), epinephrine (Asthmahaler, Bronkaid, Primatene Mist Inhaler), isoetharine (Bronkometer, Bronkosol), metaproterenol (Alupent, Metaprel), pirbuterol (Maxair), salmeterol (Serevent), or terbutaline (Brethaire, Brethine);

· heart or blood pressure medicine such as diltiazem (Cardizem, Dilacor, Tiazac) or verapamil (Calan, Covera, Isoptin, Verelan), acebutolol (Sectral), atenolol (Tenormin), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), timolol (Blocadren), and others; or

· HIV /AIDS medication such as amprenavir (Agenerase), delavirdine (Rescriptor), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir), or saquinavir (Invirase, Fortovase).

• This list is not complete and there may be another drugs that can interact with cevimeline. Speak your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start using a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about cevimeline.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.