Amprenavir (Agenerase); Antiretroviral,
Protease Inhibitor; Cap: 50, 150 mg
Soln: 15 mg/mL;
Capsules:
4-12 yrs (also 13-16 yrs if <50kg): 40 mg/kg/day PO bid or 45 mg/kg/day PO tid (max 2400 mg/day)
>12 yrs
AND >50 kg: 1200 mg PO bid
Solution:
4-12 yrs (also 13-16 yrs if < 50 kg): 45 mg/kg/day PO bid or 51 mg/kg/day PO tid (max 2800 mg/day)
>13 yrs
AND >50 kg: 1400 mg PO bid
The solution is not interchangeable with the capsules on a mg per mg basis. Severe or life-threatening rash occurs in 1% of patients. May take with or
without food.