BUDESONIDE AND FORMOTEROL INHALATION

(bue DES oh nide and for MOE te rol) Brand: Symbicort

What is the most significant information I must know about budesonide and formoterol inhalation?

• Do not use budesonide and formoterol inhalation to treat an asthma onslaught that has already begun.

• Budesonide and formoterol inhalation may magnify the risk of asthma-related death. Use only the predesigned doze of budesonide and formoterol, and do not use it for longer than your doctor recommends. Follow all patient instructions for safety use. Talk with your doctor about your individual risks and benefits in using this medication.

• Use all of your medications as directed by your doctor. Conversation with your doctor if your medications do not seem to work as well in treating or preventing attacks. Do not change your doses or medicine schedule without advice from your doctor.

• Till using budesonide and formoterol, speak your doctor if you have heart malady, tall blood pressure, a seizure mess, an infection (including herpes infection of the eyes), diabetes, tuberculosis, a thyroid mess, or an electrolyte imbalance (such as low potassium levels in your blood).

• Seek medical attention if you think any of your asthma medications are not working as well as normal. An heighten need for medicine could be an early sign of a serious asthma onslaught. If you use a peak flow meter at house, call your doctor if your numbers are lower than normal.

What is budesonide and formoterol inhalation?

• Budesonide is a steroid that reduces inflammation in the body.

• Formoterol is a bronchodilator that relaxes muscles in the airways to improve breathing.

• The combination of budesonide and formoterol is used to prevent bronchospasm in people with asthma or chronic obstructive pulmonary malady (COPD).

• Budesonide and formoterol inhalation may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till using budesonide and formoterol inhalation?

• You must not use this medicine if you are allergic to budesonide (Entocort, Pulmicort, Rhinocort) or formoterol (Foradil, Perforomist).

• To create certain you can safely use budesonide and formoterol, speak your doctor if you have any of these another conditions:

· heart malady or tall blood pressure;

· epilepsy or another seizure disorder;

· diabetes;

· herpes infection of the eyes;

· tuberculosis;

· any active infection;

· an electrolyte imbalance (such as low potassium levels in your blood); or

· a thyroid disorder.

• FDA pregnancy category C. It is not known whether budesonide and formoterol will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

• Budesonide can pass into breast milk and could harm a nursing child. Do not use budesonide and formoterol inhalation without telling your doctor if you are breast-feeding a baby.

• Budesonide can affect growth in children. Conversation with your doctor if you think your baby is not growing at a usual course while using this medication.

• Do not give this medicine to a baby younger than 12 years old.

• Long-term use of steroids may lead to bone loss (osteoporosis), especially if you smoke, if you do not exercice, if you do not get satis vitamin D or calcium in your diet, or if you have a family history of osteoporosis.

How must I use budesonide and formoterol inhalation?

• Do not use budesonide and formoterol to treat an asthma onslaught that has already begun. It will not work quick satis. Use only a fast-acting inhalation medication.

• Budesonide and formoterol comes with patient instructions for safety and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions. Always rinse your mouth after using the inhaler device.

• Prime the inhaler device till the first use by pumping 2 test sprays into the air, away from your person. Shake the inhaler for at least 5 seconds till every spray. Prime the inhaler if it has not been used for longer than 7 days, or if the inhaler has been dropped.

• Do not try to clean or take separately the inhaler device. Throw it away when the medication runs out. Do not float the medication canister in water. The doze indicator on the inhaler will turn red when there are 10 doses left in the device. Get your prescription refilled till you run out of medication completely. Always use the new device provided with the medicine when you get your prescription filled.

• It may take up to 2 weeks till your symptoms improve. Hold using the medicine as directed. Call your doctor if your symptoms do not improve after the first week of treatment, or if your symptoms get worse.

• Your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.

• Your dosage needs may change if you have surgery, are ill, are under stress, or have recently had an asthma onslaught. Do not change your doses or medicine schedule without advice from your doctor.

• If you also use a steroid medicine, do not stop using the steroid suddenly or you may have unpleasant withdrawal symptoms. Conversation with your doctor about using smaller and smaller of the steroid till stopping completely.

• Wear a medical alert tag or carry an ID card to allow others know that you may need an oral steroid in an emergency.

• Store at room temperature, away from moisture, easy, and heat. Always hold the cover on the inhaler device when not in use. Hold the medication canister away from open flame or tall heat, such as in a machine on a hot day. The canister may explode if it gets too hot. Do not puncture or burn an empty inhaler canister.

What happens if I miss a dose?

• Use the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not use extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

• Overdose can reason redness near your nose, runny nose, trouble breathing, nervousness, muscle cramps, dry mouth, nausea, vomiting, sleep problems (insomnia), tremors, chest pain, quick or pounding heartbeats, fainting, and seizure (convulsions).

What must I avoid while using budesonide and formoterol inhalation?

• Do not use a second form of formoterol (such as Foradil, Performist) or use a similar inhaled bronchodilator such as salmeterol (Serevent, Advair) or arformoterol (Brovana) unless your doctor has told you to.

• Using a steroid can lower the blood cells that help your body fight infections. Avoid being around people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medicines.

What are the possible side effects of budesonide and formoterol inhalation?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have any of these serious side effects:

· worsening asthma symptoms;

· chest pain, quick or pounding heartbeats, tremors, nervousness;

· wheezing, throat irritation, choking, or another breathing problems after using this medication;

· signs of infection such as fever, chills, sore throat, flu symptoms, light bruising or bleeding, unusual weakness;

· blurred vision, eye pain, or seeing halos near lights;

· white patches or sores in your mouth or throat; or

· dangerously tall blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

• Smaller serious side effects may include:

· headache;

· nausea, vomiting, diarrhea, upset stomach;

· back pain;

· stuffy nose;

· muscle or joint pain; or

· changes in your voice.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect budesonide and formoterol?

• Speak your doctor about all another medicines you use, especially:

· antibiotics such as azithromycin (Zithromax), clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek);

· antifungal medicine such as ketoconazole (Nizoral), or itraconazole (Sporanox);

· a diuretic (water pill);

· an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate);

· an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), doxepin (Sinequan, Silenor), nortriptyline (Pamelor), and others; or

· a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others.

• This list is not complete and another drugs may interact with budesonide and formoterol inhalation. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about budesonide and formoterol inhalation.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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